Tumor microenvironment-driven non-cell-autonomous resistance to antineoplastic treatment
出版年份 2019 全文链接
标题
Tumor microenvironment-driven non-cell-autonomous resistance to antineoplastic treatment
作者
关键词
Tumor, Non-cell-autonomous drug resistance, Tumor microenvironment, Drug resistance
出版物
Molecular Cancer
Volume 18, Issue 1, Pages -
出版商
Springer Nature
发表日期
2019-03-30
DOI
10.1186/s12943-019-0992-4
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The IGF2/IR/IGF1R Pathway in Tumor Cells and Myofibroblasts Mediates Resistance to EGFR Inhibition in Cholangiocarcinoma
- (2018) Javier Vaquero et al. CLINICAL CANCER RESEARCH
- A new approach to assess drug sensitivity in cells for novel drug discovery
- (2018) Luca Mazzarella et al. Expert Opinion on Drug Discovery
- MIR21 Drives Resistance to Heat Shock Protein 90 Inhibition in Cholangiocarcinoma
- (2018) Andrea Lampis et al. GASTROENTEROLOGY
- Targeting tumour microenvironment by tyrosine kinase inhibitor
- (2018) Hor-Yue Tan et al. Molecular Cancer
- Hypoxia-induced exosomes contribute to a more aggressive and chemoresistant ovarian cancer phenotype: a novel mechanism linking STAT3/Rab proteins
- (2018) Kalpana Deepa Priya Dorayappan et al. ONCOGENE
- Cisplatin-activated PAI-1 secretion in the cancer-associated fibroblasts with paracrine effects promoting esophageal squamous cell carcinoma progression and causing chemoresistance
- (2018) Yun Che et al. Cell Death & Disease
- The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1
- (2018) Boyi Zhang et al. Nature Communications
- Nitric Oxide Generated by Tumor-Associated Macrophages Is Responsible for Cancer Resistance to Cisplatin and Correlated With Syntaxin 4 and Acid Sphingomyelinase Inhibition
- (2018) Cristiana Perrotta et al. Frontiers in Immunology
- Three Dimensional Mixed-Cell Spheroids Mimic Stroma-Mediated Chemoresistance and Invasive Migration in hepatocellular carcinoma
- (2018) Iftikhar Ali Khawar et al. NEOPLASIA
- Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies
- (2018) Maria Apicella et al. Cell Metabolism
- Quercetin and doxorubicin co-delivery using mesoporous silica nanoparticles enhance the efficacy of gastric carcinoma chemotherapy
- (2018) Jian Fang et al. International Journal of Nanomedicine
- Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML
- (2018) Eimear O’ Reilly et al. Scientific Reports
- Phenotypic Basis for Matrix Stiffness-Dependent Chemoresistance of Breast Cancer Cells to Doxorubicin
- (2018) M. Hunter Joyce et al. Frontiers in Oncology
- Tumor microenvironment: Interactions and therapy
- (2018) Masoud Najafi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Cancer-associated fibroblasts promote progression and gemcitabine resistance via the SDF-1/SATB-1 pathway in pancreatic cancer
- (2018) Lusheng Wei et al. Cell Death & Disease
- Hypoxia-mediated mitochondria apoptosis inhibition induces temozolomide treatment resistance through miR-26a/Bad/Bax axis
- (2018) Xin Ge et al. Cell Death & Disease
- Tumor associated macrophages provide the survival resistance of tumor cells to hypoxic microenvironmental condition through IL-6 receptor-mediated signals
- (2017) Soo Kyung Jeong et al. IMMUNOBIOLOGY
- Tumour-associated macrophage-mediated survival of myeloma cells through STAT3 activation
- (2017) Nathan De Beule et al. JOURNAL OF PATHOLOGY
- Mesenchymal stem cells derived from multiple myeloma patients protect against chemotherapy through autophagy-dependent activation of NF-κB signaling
- (2017) HongLiang Yang et al. LEUKEMIA RESEARCH
- Elevated expression of SATB1 is involved in pancreatic tumorigenesis and is associated with poor patient survival
- (2017) Lei Guo et al. Molecular Medicine Reports
- Drug development in the era of precision medicine
- (2017) Sarah A. Dugger et al. NATURE REVIEWS DRUG DISCOVERY
- Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas
- (2017) D Yan et al. ONCOGENE
- Small-Molecule Screens: A Gateway to Cancer Therapeutic Agents with Case Studies of Food and Drug Administration–Approved Drugs
- (2017) Nathan P. Coussens et al. PHARMACOLOGICAL REVIEWS
- Cisplatin induces the release of extracellular vesicles from ovarian cancer cells that can induce invasiveness and drug resistance in bystander cells
- (2017) Priya Samuel et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Human cancer-associated fibroblasts enhance glutathione levels and antagonize drug-induced prostate cancer cell death
- (2017) Emarndeena H Cheteh et al. Cell Death & Disease
- Unification of de novo and acquired ibrutinib resistance in mantle cell lymphoma
- (2017) Xiaohong Zhao et al. Nature Communications
- Substrate Stiffness Influences Doxorubicin-Induced p53 Activation via ROCK2 Expression
- (2017) Takahiro Ebata et al. Biomed Research International
- Signal transducer and activator of transcription 3 as a therapeutic target for cancer and the tumor microenvironment
- (2016) Byung-Hak Kim et al. ARCHIVES OF PHARMACAL RESEARCH
- Targeting autophagy to overcome chemoresistance in acute myleogenous leukemia
- (2016) Sujan Piya et al. Autophagy
- Multidrug resistant tumour cells shed more microvesicle-like EVs and less exosomes than their drug-sensitive counterpart cells
- (2016) Vanessa Lopes-Rodrigues et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Exosome-Transmitted lncARSR Promotes Sunitinib Resistance in Renal Cancer by Acting as a Competing Endogenous RNA
- (2016) Le Qu et al. CANCER CELL
- Bone marrow PMN-MDSCs and neutrophils are functionally similar in protection of multiple myeloma from chemotherapy
- (2016) Indu R. Ramachandran et al. CANCER LETTERS
- Tumor microenvironment and cancer therapy resistance
- (2016) Yu Sun CANCER LETTERS
- Mesenchymal Stem Cell–Derived Exosomes Stimulate Cycling Quiescence and Early Breast Cancer Dormancy in Bone Marrow
- (2016) Sarah A. Bliss et al. CANCER RESEARCH
- Spatial Proximity to Fibroblasts Impacts Molecular Features and Therapeutic Sensitivity of Breast Cancer Cells Influencing Clinical Outcomes
- (2016) Andriy Marusyk et al. CANCER RESEARCH
- Erratum to: Cisplatin-induced mesenchymal stromal cells-mediated mechanism contributing to decreased antitumor effect in breast cancer cells
- (2016) Svetlana Skolekova et al. Cell Communication and Signaling
- Tumor-Associated Neutrophils Recruit Macrophages and T-Regulatory Cells to Promote Progression of Hepatocellular Carcinoma and Resistance to Sorafenib
- (2016) Shao-Lai Zhou et al. GASTROENTEROLOGY
- Phosphoproteome Profiling Reveals Molecular Mechanisms of Growth-Factor-Mediated Kinase Inhibitor Resistance in EGFR-Overexpressing Cancer Cells
- (2016) Heiner Koch et al. JOURNAL OF PROTEOME RESEARCH
- Targeting of cancer-associated fibroblasts enhances the efficacy of cancer chemotherapy by regulating the tumor microenvironment
- (2016) MINMIN LI et al. Molecular Medicine Reports
- Characterization of Cell-Type-Specific Drug Transport and Resistance of Breast Cancers Using Tumor-Microenvironment-on-Chip
- (2016) Kyeonggon Shin et al. MOLECULAR PHARMACEUTICS
- sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance
- (2016) Amanpreet Kaur et al. NATURE
- Patient-derived induced pluripotent stem cells in cancer research and precision oncology
- (2016) Eirini P Papapetrou NATURE MEDICINE
- Cytoplasmic GPER translocation in cancer-associated fibroblasts mediates cAMP/PKA/CREB/glycolytic axis to confer tumor cells with multidrug resistance
- (2016) T Yu et al. ONCOGENE
- Differential expression of PDGFRB and EGFR in microvascular proliferation in glioblastoma
- (2016) Guiyan Xu et al. TUMOR BIOLOGY
- Metabolic Symbiosis Enables Adaptive Resistance to Anti-angiogenic Therapy that Is Dependent on mTOR Signaling
- (2016) Elizabeth Allen et al. Cell Reports
- Tissue Transglutaminase Activates Cancer-Associated Fibroblasts and Contributes to Gemcitabine Resistance in Pancreatic Cancer
- (2016) Jiyoon Lee et al. NEOPLASIA
- Activated hepatic stellate cells play pivotal roles in hepatocellular carcinoma cell chemoresistance and migration in multicellular tumor spheroids
- (2016) Yeonhwa Song et al. Scientific Reports
- The role of HGF/MET and FGF/FGFR in fibroblast-derived growth stimulation and lapatinib-resistance of esophageal squamous cell carcinoma
- (2015) Shin Saito et al. BMC CANCER
- CXCR2/CXCL5 axis contributes to epithelial–mesenchymal transition of HCC cells through activating PI3K/Akt/GSK-3β/Snail signaling
- (2015) Shao-Lai Zhou et al. CANCER LETTERS
- Bone marrow derived myeloid cells orchestrate antiangiogenic resistance in glioblastoma through coordinated molecular networks
- (2015) B.R. Achyut et al. CANCER LETTERS
- Anthracyclines potentiate anti-tumor immunity: A new opportunity for chemoimmunotherapy
- (2015) Zhigang Zhang et al. CANCER LETTERS
- Tumor microenvironment: Sanctuary of the devil
- (2015) Lanlan Hui et al. CANCER LETTERS
- Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer
- (2015) Nagaraj S. Nagathihalli et al. GASTROENTEROLOGY
- CXCR4 inhibition in tumor microenvironment facilitates anti-programmed death receptor-1 immunotherapy in sorafenib-treated hepatocellular carcinoma in mice
- (2015) Yunching Chen et al. HEPATOLOGY
- Intratumoral Delivery of IL-21 Overcomes Anti-Her2/Neu Resistance through Shifting Tumor-Associated Macrophages from M2 to M1 Phenotype
- (2015) Meng Xu et al. JOURNAL OF IMMUNOLOGY
- Cycling hypoxia induces chemoresistance through the activation of reactive oxygen species-mediated B-cell lymphoma extra-long pathway in glioblastoma multiforme
- (2015) Wei-Ling Chen et al. Journal of Translational Medicine
- Glioma cells escaped from cytotoxicity of temozolomide and vincristine by communicating with human astrocytes
- (2015) Weiliang Chen et al. MEDICAL ONCOLOGY
- Therapy-induced tumour secretomes promote resistance and tumour progression
- (2015) Anna C. Obenauf et al. NATURE
- Benzyl butyl phthalate increases the chemoresistance to doxorubicin/cyclophosphamide by increasing breast cancer-associated dendritic cell-derived CXCL1/GROα and S100A8/A9
- (2015) YA-LING HSU et al. ONCOLOGY REPORTS
- Nurse-like cells mediate ibrutinib resistance in chronic lymphocytic leukemia patients
- (2015) F Boissard et al. Blood Cancer Journal
- DNA damage induces GDNF secretion in the tumor microenvironment with paracrine effects promoting prostate cancer treatment resistance
- (2015) Roland M. Huber et al. Oncotarget
- Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive N-Myc amplified human neuroblastoma cells to doxorubicin
- (2015) Lahiru Gangoda et al. Oncotarget
- Cross-talk between chronic lymphocytic leukemia (CLL) tumor B cells and mesenchymal stromal cells (MSCs): implications for neoplastic cell survival
- (2015) Valentina Trimarco et al. Oncotarget
- Microenvironmental Hypoxia regulates FLT3 expression and biology in AML
- (2015) Silvia Sironi et al. Scientific Reports
- Hypoxia-Induced Decrease in p53 Protein Level and Increase in c-jun DNA Binding Activity Results in Cancer Cell Resistance to Etoposide
- (2015) Jean-Philippe Cosse et al. NEOPLASIA
- Silencing of Suppressor of Cytokine Signaling-3 due to Methylation Results in Phosphorylation of STAT3 in Imatinib Resistant BCR-ABL Positive Chronic Myeloid Leukemia Cells
- (2014) Hamid AN Al-Jamal et al. Asian Pacific Journal of Cancer Prevention
- Targeting the Oncogenic MUC1-C Protein Inhibits Mutant EGFR-Mediated Signaling and Survival in Non-Small Cell Lung Cancer Cells
- (2014) A. Kharbanda et al. CLINICAL CANCER RESEARCH
- Podoplanin-Positive Cancer-Associated Fibroblasts in the Tumor Microenvironment Induce Primary Resistance to EGFR-TKIs in Lung Adenocarcinoma with EGFR Mutation
- (2014) Tatsuya Yoshida et al. CLINICAL CANCER RESEARCH
- Akt-Activated Endothelium Constitutes the Niche for Residual Disease and Resistance to Bevacizumab in Ovarian Cancer
- (2014) B. S. Guerrouahen et al. MOLECULAR CANCER THERAPEUTICS
- Hypoxia Increases Gefitinib-Resistant Lung Cancer Stem Cells through the Activation of Insulin-Like Growth Factor 1 Receptor
- (2014) Akiko Murakami et al. PLoS One
- Exosomes from Drug-Resistant Breast Cancer Cells Transmit Chemoresistance by a Horizontal Transfer of MicroRNAs
- (2014) Wei-xian Chen et al. PLoS One
- Hypoxia-induced miR-424 decreases tumor sensitivity to chemotherapy by inhibiting apoptosis
- (2014) D Zhang et al. Cell Death & Disease
- Drug Resistance in Cancer: An Overview
- (2014) Genevieve Housman et al. Cancers
- Apoptosis repressor with caspase recruitment domain is regulated by MAPK/PI3K and confers drug resistance and survival advantage to AML
- (2013) P. Y. Mak et al. APOPTOSIS
- The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization
- (2013) J. Hoellenriegel et al. BLOOD
- Emerging role of tumor-associated macrophages as therapeutic targets in patients with metastatic renal cell carcinoma
- (2013) Matteo Santoni et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Chemotherapy Alters Monocyte Differentiation to Favor Generation of Cancer-Supporting M2 Macrophages in the Tumor Microenvironment
- (2013) E. M. Dijkgraaf et al. CANCER RESEARCH
- CXCL5 contributes to tumor metastasis and recurrence of intrahepatic cholangiocarcinoma by recruiting infiltrative intratumoral neutrophils
- (2013) Shao-Lai Zhou et al. CARCINOGENESIS
- MiR-365 induces gemcitabine resistance in pancreatic cancer cells by targeting the adaptor protein SHC1 and pro-apoptotic regulator BAX
- (2013) Shin Hamada et al. CELLULAR SIGNALLING
- Downregulation of Stat3 in melanoma: reprogramming the immune microenvironment as an anticancer therapeutic strategy
- (2013) P U Emeagi et al. GENE THERAPY
- The phosphatidylinositol-3-kinase inhibitor NVP-BKM120 overcomes resistance signals derived from microenvironment by regulating the Akt/FoxO3a/Bim axis in chronic lymphocytic leukemia cells
- (2013) L. Rosich et al. HAEMATOLOGICA
- Differential effects of sorafenib on liver versus tumor fibrosis mediated by stromal-derived factor 1 alpha/C-X-C receptor type 4 axis and myeloid differentiation antigen-positive myeloid cell infiltration in mice
- (2013) Yunching Chen et al. HEPATOLOGY
- Association Between BRAF V600E Mutation and Mortality in Patients With Papillary Thyroid Cancer
- (2013) Mingzhao Xing et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Differential effect of hypoxia on etoposide-induced DNA damage response and p53 regulation in different cell types
- (2013) Audrey Sermeus et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Microenvironmental regulation of tumor progression and metastasis
- (2013) Daniela F Quail et al. NATURE MEDICINE
- Connexin43 confers Temozolomide resistance in human glioma cells by modulating the mitochondrial apoptosis pathway
- (2013) Paul R. Gielen et al. NEUROPHARMACOLOGY
- Macrophages mediate gemcitabine resistance of pancreatic adenocarcinoma by upregulating cytidine deaminase
- (2013) N Weizman et al. ONCOGENE
- Microenvironment mesenchymal cells protect ovarian cancer cell lines from apoptosis by inhibiting XIAP inactivation
- (2013) M Castells et al. Cell Death & Disease
- Cell-Autonomous and Non-Cell-Autonomous Mechanisms of HGF/MET-Driven Resistance to Targeted Therapies: From Basic Research to a Clinical Perspective
- (2013) S. Corso et al. Cancer Discovery
- Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
- (2012) Douglas Hanahan et al. CANCER CELL
- Cancer-Associated Fibroblasts Induce Matrix Metalloproteinase-Mediated Cetuximab Resistance in Head and Neck Squamous Cell Carcinoma Cells
- (2012) A.-C. Johansson et al. MOLECULAR CANCER RESEARCH
- Discovery of small molecule cancer drugs: Successes, challenges and opportunities
- (2012) Swen Hoelder et al. Molecular Oncology
- Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia
- (2012) Wan Zhang et al. NATURE CELL BIOLOGY
- Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth
- (2012) Mélanie Bruchard et al. NATURE MEDICINE
- Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype
- (2012) Y. Piao et al. NEURO-ONCOLOGY
- LASS2 enhances chemosensitivity of breast cancer by counteracting acidic tumor microenvironment through inhibiting activity of V-ATPase proton pump
- (2012) S Fan et al. ONCOGENE
- Targeting of distinct signaling cascades and cancer-associated fibroblasts define the efficacy of Sorafenib against prostate cancer cells
- (2012) P Kharaziha et al. Cell Death & Disease
- Circumventing Cancer Drug Resistance in the Era of Personalized Medicine
- (2012) Levi A. Garraway et al. Cancer Discovery
- Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer
- (2011) T. Shree et al. GENES & DEVELOPMENT
- Control of the senescence-associated secretory phenotype by NF- B promotes senescence and enhances chemosensitivity
- (2011) Y. Chien et al. GENES & DEVELOPMENT
- MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy
- (2011) James Finke et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Downstream molecular pathways of FLT3 in the pathogenesis of acute myeloid leukemia: biology and therapeutic implications
- (2011) Shinichiro Takahashi Journal of Hematology & Oncology
- Spleen tyrosine kinase inhibition prevents chemokine- and integrin-mediated stromal protective effects in chronic lymphocytic leukemia
- (2010) M. Buchner et al. BLOOD
- The Therapeutic Effect of Anti-HER2/neu Antibody Depends on Both Innate and Adaptive Immunity
- (2010) SaeGwang Park et al. CANCER CELL
- Tumor–stromal cell interactions and opportunities for therapeutic intervention
- (2010) Taturo Udagawa et al. CURRENT OPINION IN PHARMACOLOGY
- Survival of Human Multiple Myeloma Cells Is Dependent on MUC1 C-Terminal Transmembrane Subunit Oncoprotein Function
- (2010) L. Yin et al. MOLECULAR PHARMACOLOGY
- Cycling hypoxia increases U87 glioma cell radioresistance via ROS induced higher and long-term HIF-1 signal transduction activity
- (2010) Hsieh ONCOLOGY REPORTS
- Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion
- (2010) K. D. Grugan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autocrine TGF- and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts
- (2010) Y. Kojima et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- STAT3 tyrosine phosphorylation is critical for interleukin 1 beta and interleukin-6 production in response to lipopolysaccharide and live bacteria
- (2009) Lobelia Samavati et al. MOLECULAR IMMUNOLOGY
- Attenuated p53 activation in tumour-associated stromal cells accompanies decreased sensitivity to etoposide and vincristine
- (2008) A C Dudley et al. BRITISH JOURNAL OF CANCER
- Senescence of Activated Stellate Cells Limits Liver Fibrosis
- (2008) Valery Krizhanovsky et al. CELL
- STAT3 as a target for inducing apoptosis in solid and hematological tumors
- (2008) Khandaker Al Zaid Siddiquee et al. CELL RESEARCH
- Modulation of several waves of gene expression during FGF-1 induced epithelial-mesenchymal transition of carcinoma cells
- (2008) Clotilde Billottet et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Induction of MGMT expression is associated with temozolomide resistance in glioblastoma xenografts
- (2008) Gaspar J. Kitange et al. NEURO-ONCOLOGY
- Platinum-Based Chemotherapy plus Cetuximab in Head and Neck Cancer
- (2008) Jan B. Vermorken et al. NEW ENGLAND JOURNAL OF MEDICINE
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