Differential effect of hypoxia on etoposide-induced DNA damage response and p53 regulation in different cell types

Hypoxia-Induced Decrease in p53 Protein Level and Increase in c-jun DNA Binding Activity Results in Cancer Cell Resistance to Etoposide

(2015) Jean-Philippe Cosse et al.   NEOPLASIA

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

NFBD1/MDC1, 53BP1 and BRCA1 have both redundant and unique roles in the ATM pathway

(2011) Kathleen A. Wilson et al.   CELL CYCLE

Reciprocal influence of the p53 and the hypoxic pathways

(2011) A Sermeus et al.   Cell Death & Disease

MicroRNA-1285 inhibits the expression of p53 by directly targeting its 3′ untranslated region

(2010) Shu Tian et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

miR-33-mediated downregulation of p53 controls hematopoietic stem cell self-renewal

(2010) Antonio Herrera-Merchan et al.   CELL CYCLE

MDC1: The art of keeping things in focus

(2010) Stephanie Jungmichel et al.   CHROMOSOMA

Regulation of tumor suppressor p53 at the RNA level

(2010) Anna Vilborg et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Negative Regulation of Tumor Suppressor p53 by MicroRNA miR-504

(2010) Wenwei Hu et al.   MOLECULAR CELL

miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma

(2010) Alexander Swarbrick et al.   NATURE MEDICINE

Wip1 phosphatase is associated with chromatin and dephosphorylates γH2AX to promote checkpoint inhibition

(2010) L Macůrek et al.   ONCOGENE

Ubiquitin-independent p53 proteasomal degradation

(2009) P Tsvetkov et al.   CELL DEATH AND DIFFERENTIATION

The multiple levels of regulation by p53 ubiquitination

(2009) J T Lee et al.   CELL DEATH AND DIFFERENTIATION

Taking the time to make important decisions: The checkpoint effector kinases Chk1 and Chk2 and the DNA damage response

(2009) Travis H. Stracker et al.   DNA REPAIR

Hypoxia prevents etoposide-induced DNA damage in cancer cells through a mechanism involving hypoxia-inducible factor 1

(2009) R. Sullivan et al.   MOLECULAR CANCER THERAPEUTICS

Topoisomerase IIα-dependent induction of a persistent DNA damage response in response to transient etoposide exposure

(2009) Sébastien Soubeyrand et al.   Molecular Oncology

Transcription-independent p53 apoptosis: an alternative route to death

(2009) Daniel Speidel   TRENDS IN CELL BIOLOGY

p53 is localized to a sub-nucleolar compartment after proteasomal inhibition in an energy-dependent manner

(2008) O. Karni-Schmidt et al.   JOURNAL OF CELL SCIENCE

Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity

(2008) Audrey Sermeus et al.   Molecular Cancer