Microenvironment mesenchymal cells protect ovarian cancer cell lines from apoptosis by inhibiting XIAP inactivation

AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins, inhibits progression of human ovarian cancer

(2012) Melissa K. Brunckhorst et al.   CANCER BIOLOGY & THERAPY

Ovarian ascites-derived Hospicells promote angiogenesis via activation of macrophages

(2012) Magali Castells et al.   CANCER LETTERS

Implication of Tumor Microenvironment in Chemoresistance: Tumor-Associated Stromal Cells Protect Tumor Cells from Cell Death

(2012) Magali Castells et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Fibroblasts share mesenchymal phenotypes with stem cells, but lack their differentiation and colony-forming potential

(2011) Eckhard Alt et al.   BIOLOGY OF THE CELL

Mesenchymal Stem Cells Induce Resistance to Chemotherapy through the Release of Platinum-Induced Fatty Acids

(2011) Jeanine M.L. Roodhart et al.   CANCER CELL

Autocrine production of interleukin-8 confers cisplatin and paclitaxel resistance in ovarian cancer cells

(2011) Yue Wang et al.   CYTOKINE

Multidrug resistance proteins (MRPs/ABCCs) in cancer chemotherapy and genetic diseases

(2011) Zhe-Sheng Chen et al.   FEBS Journal

A Potent and Orally Active Antagonist (SM-406/AT-406) of Multiple Inhibitor of Apoptosis Proteins (IAPs) in Clinical Development for Cancer Treatment

(2011) Qian Cai et al.   JOURNAL OF MEDICINAL CHEMISTRY

Bone marrow stromal cells protect myeloma cells from bortezomib induced apoptosis by suppressing microRNA-15a expression

(2011) Mu Hao et al.   LEUKEMIA & LYMPHOMA

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

PI3K: a rational target for ovarian cancer therapy?

(2010) Paul Dent et al.   CANCER BIOLOGY & THERAPY

Autocrine production of interleukin-6 confers cisplatin and paclitaxel resistance in ovarian cancer cells

(2010) Yue Wang et al.   CANCER LETTERS

Prostaglandin E2Activates and Utilizes mTORC2 as a Central Signaling Locus for the Regulation of Mast Cell Chemotaxis and Mediator Release

(2010) Hye Sun Kuehn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance

(2009) A. V. Kurtova et al.   BLOOD

Adult human mesenchymal stem cells enhance breast tumorigenesis and promote hormone independence

(2009) Lyndsay V. Rhodes et al.   BREAST CANCER RESEARCH AND TREATMENT

Multiple Myeloma Bone Marrow Niche

(2009) Grzegorz Basak et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression

(2009) Erika L. Spaeth et al.   PLoS One

TGF- receptor kinase inhibitor LY2109761 reverses the anti-apoptotic effects of TGF-1 in myelo-monocytic leukaemic cells co-cultured with stromal cells

(2008) Yuanyuan Xu et al.   BRITISH JOURNAL OF HAEMATOLOGY

CXCR4 up-regulation by imatinib induces chronic myelogenous leukemia (CML) cell migration to bone marrow stroma and promotes survival of quiescent CML cells

(2008) L. Jin et al.   MOLECULAR CANCER THERAPEUTICS

IAPs: What's in a Name?

(2008) Srinivasa M. Srinivasula et al.   MOLECULAR CELL

Oncologic Trogocytosis of an Original Stromal Cells Induces Chemoresistance of Ovarian Tumours

(2008) Arash Rafii et al.   PLoS One

Cancer-Derived Lysophosphatidic Acid Stimulates Differentiation of Human Mesenchymal Stem Cells to Myofibroblast-Like Cells

(2007) Eun Su Jeon et al.   STEM CELLS