Pharmacological doses of melatonin impede cognitive decline in tau‐related Alzheimer models, once tauopathy is initiated, by restoring the autophagic flux
出版年份 2019 全文链接
标题
Pharmacological doses of melatonin impede cognitive decline in tau‐related Alzheimer models, once tauopathy is initiated, by restoring the autophagic flux
作者
关键词
-
出版物
JOURNAL OF PINEAL RESEARCH
Volume -, Issue -, Pages e12578
出版商
Wiley
发表日期
2019-04-04
DOI
10.1111/jpi.12578
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Protective roles of melatonin against the amyloid-dependent development of Alzheimer’s disease: A critical review
- (2018) Bruno Vincent PHARMACOLOGICAL RESEARCH
- Melatonin as an endogenous regulator of diseases: The role of autophagy
- (2018) Ali Roohbakhsh et al. PHARMACOLOGICAL RESEARCH
- Tau and neuroinflammation: What impact for Alzheimer's Disease and Tauopathies?
- (2018) Cyril Laurent et al. Biomedical Journal
- The Implications of Autophagy in Alzheimer's Disease
- (2018) Tadanori Hamano et al. Current Alzheimer Research
- Tau-based therapies in neurodegeneration: opportunities and challenges
- (2017) Chuanzhou Li et al. NATURE REVIEWS DRUG DISCOVERY
- Melatonin reduces hypoxic-ischaemic (HI) induced autophagy and apoptosis: An in vivo and in vitro investigation in experimental models of neonatal HI brain injury
- (2017) Yingying Hu et al. NEUROSCIENCE LETTERS
- The role of ubiquitin proteasomal system and autophagy-lysosome pathway in Alzheimer’s disease
- (2017) Yuan Zhang et al. REVIEWS IN THE NEUROSCIENCES
- Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy
- (2016) Matteo Bordi et al. Autophagy
- Melatonin and Synthetic Melatoninergic Agonists in Psychiatric and Age-associated Disorders: Successful and Unsuccessful Approaches
- (2016) Rüdiger Hardeland CURRENT PHARMACEUTICAL DESIGN
- Meta-analysis of randomized, double-blind, placebo-controlled trials of melatonin in Alzheimer's disease
- (2016) Yuan-Yuan Wang et al. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
- Melatonin attenuates traumatic brain injury-induced inflammation: a possible role for mitophagy
- (2016) Chao Lin et al. JOURNAL OF PINEAL RESEARCH
- Melatonin antagonizes cadmium-induced neurotoxicity by activating the transcription factor EB-dependent autophagy-lysosome machinery in mouse neuroblastoma cells
- (2016) Min Li et al. JOURNAL OF PINEAL RESEARCH
- A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions
- (2016) Siân Baker et al. Acta Neuropathologica Communications
- Autophagic and lysosomal defects in human tauopathies: analysis of post-mortem brain from patients with familial Alzheimer disease, corticobasal degeneration and progressive supranuclear palsy
- (2016) Antonio Piras et al. Acta Neuropathologica Communications
- Melatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/α-synuclein aggregation
- (2015) Ling-Yan Su et al. Autophagy
- Melatonin protects against chronic intermittent hypoxia-induced cardiac hypertrophy by modulating autophagy through the 5′ adenosine monophosphate-activated protein kinase pathway
- (2015) Sheng Xie et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain
- (2015) Nicole Maphis et al. BRAIN
- Melatonin regulates the autophagic flux via activation of alpha-7 nicotinic acetylcholine receptors
- (2015) Jae-Kyo Jeong et al. JOURNAL OF PINEAL RESEARCH
- Melatonin and endoplasmic reticulum stress: relation to autophagy and apoptosis
- (2015) Anna Fernández et al. JOURNAL OF PINEAL RESEARCH
- Subthreshold Concentrations of Melatonin and Galantamine Improves Pathological AD-Hallmarks in Hippocampal Organotypic Cultures
- (2015) I. Buendia et al. MOLECULAR NEUROBIOLOGY
- Exogenous melatonin for sleep disorders in neurodegenerative diseases: a meta-analysis of randomized clinical trials
- (2015) Wei Zhang et al. NEUROLOGICAL SCIENCES
- Autophagy in Alzheimer’s disease
- (2015) Ameneh Zare-shahabadi et al. REVIEWS IN THE NEUROSCIENCES
- Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB
- (2014) V. A. Polito et al. EMBO Molecular Medicine
- Melatonin attenuates D-galactose-induced memory impairment, neuroinflammation and neurodegeneration via RAGE/NF-KB/JNK signaling pathway in aging mouse model
- (2014) Tahir Ali et al. JOURNAL OF PINEAL RESEARCH
- Molecular and Cellular Mechanism of Okadaic Acid (OKA)-Induced Neurotoxicity: A Novel Tool for Alzheimer’s Disease Therapeutic Application
- (2014) Pradip K. Kamat et al. MOLECULAR NEUROBIOLOGY
- mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies
- (2013) Antonella Caccamo et al. AGING CELL
- Autophagosomes form at ER–mitochondria contact sites
- (2013) Maho Hamasaki et al. NATURE
- Neuropathological Alterations in Alzheimer Disease
- (2013) A. Serrano-Pozo et al. Cold Spring Harbor Perspectives in Medicine
- Tau Clearance Mechanisms and Their Possible Role in the Pathogenesis of Alzheimer Disease
- (2013) Adrianne S. Chesser et al. Frontiers in Neurology
- Melatonin-induced autophagy protects against human prion protein-mediated neurotoxicity
- (2012) Jae-Kyo Jeong et al. JOURNAL OF PINEAL RESEARCH
- PP2A blockade inhibits autophagy and causes intraneuronal accumulation of ubiquitinated proteins
- (2012) Amandine Magnaudeix et al. NEUROBIOLOGY OF AGING
- Melatonin Antioxidative Defense: Therapeutical Implications for Aging and Neurodegenerative Processes
- (2012) Seithikurippu R. Pandi-Perumal et al. NEUROTOXICITY RESEARCH
- Primary lysosomal dysfunction causes cargo-specific deficits of axonal transport leading to Alzheimer-like neuritic dystrophy
- (2011) SooYeon Lee et al. Autophagy
- Regulation of the ischemia-induced autophagy-lysosome processes by nitrosative stress in endothelial cells
- (2011) Feng Han et al. JOURNAL OF PINEAL RESEARCH
- Melatonin attenuates kainic acid-induced neurotoxicity in mouse hippocampus via inhibition of autophagy and α-synuclein aggregation
- (2011) Chia-Fu Chang et al. JOURNAL OF PINEAL RESEARCH
- Alzheimer’s disease: pathological mechanisms and the beneficial role of melatonin
- (2011) Sergio A. Rosales-Corral et al. JOURNAL OF PINEAL RESEARCH
- Autophagic degradation of tau in primary neurons and its enhancement by trehalose
- (2011) Ulrike Krüger et al. NEUROBIOLOGY OF AGING
- Autophagy failure in Alzheimer's disease—locating the primary defect
- (2011) Ralph A. Nixon et al. NEUROBIOLOGY OF DISEASE
- TFEB Links Autophagy to Lysosomal Biogenesis
- (2011) C. Settembre et al. SCIENCE
- Clinical Uses of Melatonin: Evaluation of Human Trials
- (2010) E.J. Sanchez-Barcelo et al. CURRENT MEDICINAL CHEMISTRY
- Clinical Aspects of Melatonin Intervention in Alzheimers Disease Progression
- (2010) Daniel P. Cardinali et al. Current Neuropharmacology
- IκBβ is an essential co-activator for LPS-induced IL-1β transcription in vivo
- (2010) Melanie Scheibel et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Melatonin reduces membrane rigidity and oxidative damage in the brain of SAMP8 mice
- (2010) J.J. García et al. NEUROBIOLOGY OF AGING
- Generation of Tau Aggregates and Clearance by Autophagy in an Inducible Cell Model of Tauopathy
- (2010) Y. Wang et al. Neurodegenerative Diseases
- Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression
- (2008) Tadanori Hamano et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Melatonin attenuates methamphetamine-induced deactivation of the mammalian target of rapamycin signaling to induce autophagy in SK-N-SH cells
- (2008) Patthara Kongsuphol et al. JOURNAL OF PINEAL RESEARCH
- Melatonin protects the mitochondria from oxidative damage reducing oxygen consumption, membrane potential, and superoxide anion production
- (2008) Ana López et al. JOURNAL OF PINEAL RESEARCH
- Dose translation from animal to human studies revisited
- (2007) Shannon Reagan-Shaw et al. FASEB JOURNAL
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