A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions

Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC’s afferent and efferent connections

(2015) Michiyo Iba et al.   ACTA NEUROPATHOLOGICA

Transgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex

(2015) Michael J. Yetman et al.   Brain Structure & Function

Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity

(2015) S. Wegmann et al.   EMBO JOURNAL

Spreading of pathology in neurodegenerative diseases: a focus on human studies

(2015) Johannes Brettschneider et al.   NATURE REVIEWS NEUROSCIENCE

Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer’s disease mouse model

(2015) Gerhard Leinenga et al.   Science Translational Medicine

Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation

(2015) Sara Calafate et al.   Cell Reports

The cell biology of prion-like spread of protein aggregates: mechanisms and implication in neurodegeneration

(2015) Maddalena Costanzo et al.   BIOCHEMICAL JOURNAL

Spreading of tau pathology in Alzheimer's disease by cell-to-cell transmission

(2013) Nguyen-Vi Mohamed et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Neuroprotective effect of curcumin on okadaic acid induced memory impairment in mice

(2013) N. Rajasekar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Synthetic Tau Fibrils Mediate Transmission of Neurofibrillary Tangles in a Transgenic Mouse Model of Alzheimer's-Like Tauopathy

(2013) M. Iba et al.   JOURNAL OF NEUROSCIENCE

Okadaic acid induced neurotoxicity: An emerging tool to study Alzheimer's disease pathology

(2013) Pradip K. Kamat et al.   NEUROTOXICOLOGY

Brain homogenates from human tauopathies induce tau inclusions in mouse brain

(2013) Florence Clavaguera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

(2012) Alix de Calignon et al.   NEURON

The Spread of Neurodegenerative Disease

(2012) John Hardy et al.   NEW ENGLAND JOURNAL OF MEDICINE

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

Amygdala atrophy is prominent in early Alzheimer's disease and relates to symptom severity

(2011) Stéphane P. Poulin et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

An okadaic acid-induced model of tauopathy and cognitive deficiency

(2010) Zhang Zhang et al.   BRAIN RESEARCH

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models

(2010) J. van Eersel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transmission and spreading of tauopathy in transgenic mouse brain

(2009) Florence Clavaguera et al.   NATURE CELL BIOLOGY

Divergent phosphorylation pattern of tau in P301L tau transgenic mice

(2008) Natasha Deters et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Animal models of Alzheimer's disease and frontotemporal dementia

(2008) Jürgen Götz et al.   NATURE REVIEWS NEUROSCIENCE

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

(2008) L. M. Ittner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA