Stories of spinster with various faces: from courtship rejection to tumor metastasis rejection

S1P transporter SPNS2 regulates proper postnatal retinal morphogenesis

(2018) Chao Fang et al.   FASEB JOURNAL

Biological function of SPNS2: From zebrafish to human

(2018) Xiao Zhu et al.   MOLECULAR IMMUNOLOGY

Lipid metabolic perturbation is an early-onset phenotype in adult spinster mutants: a Drosophila model for lysosomal storage disorders

(2017) Sarita Hebbar et al.   MOLECULAR BIOLOGY OF THE CELL

Genome-wide in vivo screen identifies novel host regulators of metastatic colonization

(2017) Louise van der Weyden et al.   NATURE

Classification Systems of Secondary Active Transporters

(2017) Emelie Perland et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression

(2017) Emelie Perland et al.   Open Biology

L-leucine and SPNS1 coordinately ameliorate dysfunction of autophagy in mouse and human Niemann-Pick type C disease

(2017) Hiroko Yanagisawa et al.   Scientific Reports

Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase

(2016) Tomoyuki Sasaki et al.   Autophagy

VCP-dependent muscle degeneration is linked to defects in a dynamic tubular lysosomal network in vivo

(2015) Alyssa E Johnson et al.   eLife

Elephant shark genome provides unique insights into gnathostome evolution

(2014) Byrappa Venkatesh et al.   NATURE

Sphingolipid lysosomal storage disorders

(2014) Frances M. Platt   NATURE

Critical Role of Spns2, a Sphingosine-1-Phosphate Transporter, in Lung Cancer Cell Survival and Migration

(2014) Eric Bradley et al.   PLoS One

Spinster Homolog 2 (Spns2) Deficiency Causes Early Onset Progressive Hearing Loss

(2014) Jing Chen et al.   PLoS Genetics

Aberrant Autolysosomal Regulation Is Linked to The Induction of Embryonic Senescence: Differential Roles of Beclin 1 and p53 in Vertebrate Spns1 Deficiency

(2014) Tomoyuki Sasaki et al.   PLoS Genetics

Molecular and physiological functions of sphingosine 1-phosphate transporters

(2013) Tsuyoshi Nishi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Select interneuron clusters determine female sexual receptivity in Drosophila

(2013) Akira Sakurai et al.   Nature Communications

C13C4.5/Spinster, an evolutionarily conserved protein that regulates fertility in C. elegans through a lysosome-mediated lipid metabolism process

(2013) Mei Han et al.   Protein & Cell

Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network

(2012) Masayuki Nagahashi et al.   FASEB JOURNAL

The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice

(2012) Shigetomo Fukuhara et al.   JOURNAL OF CLINICAL INVESTIGATION

The Role of Sphingosine-1-Phosphate Transporter Spns2 in Immune System Function

(2012) A. Nijnik et al.   JOURNAL OF IMMUNOLOGY

Mouse SPNS2 Functions as a Sphingosine-1-Phosphate Transporter in Vascular Endothelial Cells

(2012) Yu Hisano et al.   PLoS One

The Transporter Spns2 Is Required for Secretion of Lymph but Not Plasma Sphingosine-1-Phosphate

(2012) Alejandra Mendoza et al.   Cell Reports

Invertebrate models of lysosomal storage disease: what have we learned so far?

(2011) Samantha Hindle et al.   INVERTEBRATE NEUROSCIENCE

Sphingosine kinases and their metabolites modulate endolysosomal trafficking in photoreceptors

(2011) Ikuko Yonamine et al.   JOURNAL OF CELL BIOLOGY

Roles of sphingolipids in Drosophila development and disease

(2011) Rachel Kraut   JOURNAL OF NEUROCHEMISTRY

Spinster Controls Dpp Signaling during Glial Migration in the Drosophila Eye

(2011) Y. Yuva-Aydemir et al.   JOURNAL OF NEUROSCIENCE

Oxidative stress induces overgrowth of the Drosophila neuromuscular junction

(2011) V. J. Milton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spinster is required for autophagic lysosome reformation and mTOR reactivation following starvation

(2011) Y. Rong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phenotypic interactions of spinster with the genes encoding proteins for cell death control in Drosophila melanogaster

(2010) Akira Sakurai et al.   ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY

Termination of autophagy and reformation of lysosomes regulated by mTOR

(2010) Li Yu et al.   NATURE

Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

(2009) Paul Saftig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Spinster Homolog, Two of Hearts, Is Required for Sphingosine 1-Phosphate Signaling in Zebrafish

(2008) Nick Osborne et al.   CURRENT BIOLOGY

The Sphingolipid Transporter Spns2 Functions in Migration of Zebrafish Myocardial Precursors

(2008) A. Kawahara et al.   SCIENCE

The Identification of Zebrafish Mutants Showing Alterations in Senescence-Associated Biomarkers

(2008) Shuji Kishi et al.   PLoS Genetics