Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression

Classification Systems of Secondary Active Transporters

(2017) Emelie Perland et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The gene expression of numerous SLC transporters is altered in the immortalized hypothalamic cell line N25/2 following amino acid starvation

(2017) Sofie V. Hellsten et al.   FEBS Open Bio

Putative Membrane-Bound Transporters MFSD14A and MFSD14B Are Neuronal and Affected by Nutrient Availability

(2017) Emilia Lekholm et al.   Frontiers in Molecular Neuroscience

Synaptic Vesicle Glycoprotein 2A Ligands in the Treatment of Epilepsy and Beyond

(2016) Wolfgang Löscher et al.   CNS DRUGS

Structural Insights into the Transport Mechanism of the Human Sodium-dependent Lysophosphatidylcholine Transporter MFSD2A

(2016) Debra Q. Y. Quek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake

(2016) Emelie Perland et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Understanding transport by the major facilitator superfamily (MFS): structures pave the way

(2016) Esben M. Quistgaard et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mfsd2a-based pharmacological strategies for drug delivery across the blood–brain barrier

(2016) Jing-Zhang Wang et al.   PHARMACOLOGICAL RESEARCH

SLC transporters: structure, function, and drug discovery

(2016) Claire Colas et al.   MedChemComm

The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly Expressed in the Mouse Brain and Have a Potential Role in Energy Homeostasis

(2016) Emelie Perland et al.   PLoS One

The human transmembrane proteome

(2015) László Dobson et al.   Biology Direct

Role of electrostatic interactions for ligand recognition and specificity of peptide transporters

(2015) Rajendra Boggavarapu et al.   BMC BIOLOGY

A Call for Systematic Research on Solute Carriers

(2015) Adrián César-Razquin et al.   CELL

Functional characterisation of a TLR accessory protein, UNC93B1, in Atlantic salmon (Salmo salar)

(2015) P.T. Lee et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Lysosomal dysfunction and impaired autophagy in a novel mouse model deficient for the lysosomal membrane protein Cln7

(2015) Laura Brandenstein et al.   HUMAN MOLECULAR GENETICS

SLC transporters as therapeutic targets: emerging opportunities

(2015) Lawrence Lin et al.   NATURE REVIEWS DRUG DISCOVERY

CCTOP: a Consensus Constrained TOPology prediction web server

(2015) László Dobson et al.   NUCLEIC ACIDS RESEARCH

The EMBL-EBI bioinformatics web and programmatic tools framework

(2015) Weizhong Li et al.   NUCLEIC ACIDS RESEARCH

The Pfam protein families database: towards a more sustainable future

(2015) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies

(2014) Alexandros Stamatakis   BIOINFORMATICS

The Human Synaptic Vesicle Protein, SV2A, Functions as a Galactose Transporter inSaccharomyces cerevisiae

(2014) Marianna Madeo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mfsd2a is critical for the formation and function of the blood–brain barrier

(2014) Ayal Ben-Zvi et al.   NATURE

Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid

(2014) Long N. Nguyen et al.   NATURE

Ensembl 2015

(2014) Fiona Cunningham et al.   NUCLEIC ACIDS RESEARCH

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

(2014) Marco Biasini et al.   NUCLEIC ACIDS RESEARCH

FRET-Assisted Determination of CLN3 Membrane Topology

(2014) Ewa Ratajczak et al.   PLoS One

Structure-based mechanism for Na+/melibiose symport by MelB

(2014) Abdul S. Ethayathulla et al.   Nature Communications

Selective Suppression of Th2 Cell-Mediated Lung Eosinophilic Inflammation by Anti-Major Facilitator Super Family Domain Containing 10 Monoclonal Antibody

(2014) Tomoe Nishimura et al.   ALLERGOLOGY INTERNATIONAL

Profiling Solute Carrier Transporters in the Human Blood–Brain Barrier

(2013) E G Geier et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Synaptic vesicle protein 2A: basic facts and role in synaptic function

(2013) Julieta Griselda Mendoza-Torreblanca et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied toProteopedia

(2013) Robert M. Hanson et al.   ISRAEL JOURNAL OF CHEMISTRY

An Extended Proteome Map of the Lysosomal Membrane Reveals Novel Potential Transporters

(2013) Agnès Chapel et al.   MOLECULAR & CELLULAR PROTEOMICS

Solute carriers as drug targets: Current use, clinical trials and prospective

(2013) Mathias Rask-Andersen et al.   MOLECULAR ASPECTS OF MEDICINE

Heme and FLVCR-related transporter families SLC48 and SLC49

(2013) Anwar A. Khan et al.   MOLECULAR ASPECTS OF MEDICINE

The ABCs of membrane transporters in health and disease (SLC series): Introduction

(2013) Matthias A. Hediger et al.   MOLECULAR ASPECTS OF MEDICINE

SLC17: A functionally diverse family of organic anion transporters

(2013) Richard J. Reimer   MOLECULAR ASPECTS OF MEDICINE

SLC6 transporters: Structure, function, regulation, disease association and therapeutics

(2013) Akula Bala Pramod et al.   MOLECULAR ASPECTS OF MEDICINE

Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects

(2013) Helgi B. Schiöth et al.   MOLECULAR ASPECTS OF MEDICINE

The Transporter Classification Database

(2013) Milton H. Saier et al.   NUCLEIC ACIDS RESEARCH

The SLC38 family of sodium–amino acid co-transporters

(2013) Stefan Bröer   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Structure of the YajR transporter suggests a transport mechanism based on the conserved motif A

(2013) Daohua Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The major facilitator superfamily (MFS) revisited

(2012) Vamsee S. Reddy et al.   FEBS Journal

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Insights into the regulation of protein abundance from proteomic and transcriptomic analyses

(2012) Christine Vogel et al.   NATURE REVIEWS GENETICS

Major Facilitator Superfamily Domain-Containing Protein 2a (MFSD2A) Has Roles in Body Growth, Motor Function, and Lipid Metabolism

(2012) Justin H. Berger et al.   PLoS One

MrBayes 3.2: Efficient Bayesian Phylogenetic Inference and Model Choice Across a Large Model Space

(2012) Fredrik Ronquist et al.   SYSTEMATIC BIOLOGY

Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software

(2011) Lee Kamentsky et al.   BIOINFORMATICS

Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways

(2011) Michela Palmieri et al.   HUMAN MOLECULAR GENETICS

Algae and humans share a molybdate transporter

(2011) M. Tejada-Jimenez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BEAGLE: An Application Programming Interface and High-Performance Computing Library for Statistical Phylogenetics

(2011) Daniel L. Ayres et al.   SYSTEMATIC BIOLOGY

Accelerated Profile HMM Searches

(2011) Sean R. Eddy   PLoS Computational Biology

Long evolutionary conservation and considerable tissue specificity of several atypical solute carrier transporters

(2010) Smitha Sreedharan et al.   GENE

Quantitative Comparison of Glutamatergic and GABAergic Synaptic Vesicles Unveils Selectivity for Few Proteins Including MAL2, a Novel Synaptic Vesicle Protein

(2010) M. Gronborg et al.   JOURNAL OF NEUROSCIENCE

The Solute Carrier Families Have a Remarkably Long Evolutionary History with the Majority of the Human Families Present before Divergence of Bilaterian Species

(2010) P. J. Hoglund et al.   MOLECULAR BIOLOGY AND EVOLUTION

Towards a knowledge-based Human Protein Atlas

(2010) Mathias Uhlen et al.   NATURE BIOTECHNOLOGY

Lysosomal Targeting of the CLN7 Membrane Glycoprotein and Transport Via the Plasma Membrane Require a Dileucine Motif

(2010) Pieter Steenhuis et al.   TRAFFIC

Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin

(2009) Markus Almén et al.   BMC BIOLOGY

SVOP Is a Nucleotide Binding Protein

(2009) Jia Yao et al.   PLoS One

Ins and Outs of Major Facilitator Superfamily Antiporters

(2008) Christopher J. Law et al.   Annual Review of Microbiology

Expression and function of TETRAN, a new type of membrane transporter

(2008) Hironori Ushijima et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mfsd2aencodes a novel major facilitator superfamily domain-containing protein highly induced in brown adipose tissue during fasting and adaptive thermogenesis

(2008) Martin Angers et al.   BIOCHEMICAL JOURNAL

The solute carrier (SLC) complement of the human genome: Phylogenetic classification reveals four major families

(2008) Robert Fredriksson et al.   FEBS LETTERS

The transmembrane topology of Batten disease protein CLN3 determined by consensus computational prediction constrained by experimental data

(2008) Timothy Nugent et al.   FEBS LETTERS

Characterization of mouse synaptic vesicle-2-associated protein (Msvop) specifically expressed in the mouse central nervous system

(2008) Eun Young Cho et al.   GENE