TRPM2 Channel in Microglia as a New Player in Neuroinflammation Associated With a Spectrum of Central Nervous System Pathologies
出版年份 2019 全文链接
标题
TRPM2 Channel in Microglia as a New Player in Neuroinflammation Associated With a Spectrum of Central Nervous System Pathologies
作者
关键词
-
出版物
Frontiers in Pharmacology
Volume 10, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2019-03-12
DOI
10.3389/fphar.2019.00239
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Transient receptor potential melastatin 2 governs stress-induced depressive-like behaviors
- (2019) Seung Yeon Ko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Increasing the TRPM2 Channel Expression in Human Neuroblastoma SH-SY5Y Cells Augments the Susceptibility to ROS-Induced Cell Death
- (2019) Xinfang An et al. Cells
- The TRPM2 channel nexus from oxidative damage to Alzheimer’s pathologies: An emerging novel intervention target for age-related dementia
- (2018) Lin-Hua Jiang et al. AGEING RESEARCH REVIEWS
- TRPM2 dependence of ROS-induced NLRP3 activation in Alzheimer's disease
- (2018) Malihe Aminzadeh et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- TRPM2 Channel Aggravates CNS Inflammation and Cognitive Impairment via Activation of Microglia in Chronic Cerebral Hypoperfusion
- (2018) Jun Miyanohara et al. JOURNAL OF NEUROSCIENCE
- Melastatin-related transient receptor potential 2 channel in Aβ42-induced neuroinflammation: implications to Alzheimer’s disease mechanism and development of therapeutics
- (2018) Lin-Hua Jiang et al. Neural Regeneration Research
- Functional and structural damage of neurons by innate immune mechanisms during neurodegeneration
- (2018) Christina Ising et al. Cell Death & Disease
- Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation
- (2018) Zhe Zhang et al. eLife
- Microglial Dynamics During Human Brain Development
- (2018) David A. Menassa et al. Frontiers in Immunology
- Single‐cell transcriptomics reveals distinct inflammation‐induced microglia signatures
- (2018) Carole Sousa et al. EMBO REPORTS
- A critical role of the transient receptor potential melastatin 2 channel in a positive feedback mechanism for reactive oxygen species-induced delayed cell death
- (2018) Xin Li et al. JOURNAL OF CELLULAR PHYSIOLOGY
- TRPM2 exacerbates central nervous system inflammation in experimental autoimmune encephalomyelitis by increasing production of CXCL2 chemokines
- (2018) Masato Tsutsui et al. JOURNAL OF NEUROSCIENCE
- Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium
- (2018) Yihe Huang et al. NATURE
- Inflammasome signalling in brain function and neurodegenerative disease
- (2018) Michael T. Heneka et al. NATURE REVIEWS NEUROSCIENCE
- Depression following a traumatic brain injury: uncovering cytokine dysregulation as a pathogenic mechanism
- (2018) AdamD Bachstetter et al. Neural Regeneration Research
- Bidirectional Microglia–Neuron Communication in Health and Disease
- (2018) Zsuzsanna Szepesi et al. Frontiers in Cellular Neuroscience
- Microglia and the Brain: Complementary Partners in Development and Disease
- (2018) Timothy R. Hammond et al. Annual Review of Cell and Developmental Biology
- Unravelling the glial response in the pathogenesis of Alzheimer's disease
- (2018) James D. Alibhai et al. FASEB JOURNAL
- Glia as architects of central nervous system formation and function
- (2018) Nicola J. Allen et al. SCIENCE
- Structures and gating mechanism of human TRPM2
- (2018) Longfei Wang et al. SCIENCE
- Microglia in Central Nervous System Inflammation and Multiple Sclerosis Pathology
- (2018) Sofie Voet et al. TRENDS IN MOLECULAR MEDICINE
- Transient receptor potential melastatin 2 channels (TRPM2) mediate neonatal hypoxic-ischemic brain injury in mice
- (2017) Sammen Huang et al. EXPERIMENTAL NEUROLOGY
- TRPM2 a potential drug target to retard oxidative stress
- (2017) Zemeng Feng Frontiers in Bioscience-Landmark
- A critical role of TRPM2 channel in Aβ42 -induced microglial activation and generation of tumor necrosis factor-α
- (2017) Sharifah Alawieyah Syed Mortadza et al. GLIA
- Microglia in steady state
- (2017) Katrin Kierdorf et al. JOURNAL OF CLINICAL INVESTIGATION
- Microglia emerge as central players in brain disease
- (2017) Michael W Salter et al. NATURE MEDICINE
- Oxytocin release via activation of TRPM2 and CD38 in the hypothalamus during hyperthermia in mice: Implication for autism spectrum disorder
- (2017) Haruhiro Higashida et al. NEUROCHEMISTRY INTERNATIONAL
- Neuroimmunology of Traumatic Brain Injury: Time for a Paradigm Shift
- (2017) Yasir N. Jassam et al. NEURON
- Purinergic signaling in microglia in the pathogenesis of neuropathic pain
- (2017) Kazuhide INOUE PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- NLRP3 Inflammasome in Neurological Diseases, from Functions to Therapies
- (2017) Limin Song et al. Frontiers in Cellular Neuroscience
- Glial Cells and Their Function in the Adult Brain: A Journey through the History of Their Ablation
- (2017) Sarah Jäkel et al. Frontiers in Cellular Neuroscience
- Signalling mechanisms mediating Zn2+-induced TRPM2 channel activation and cell death in microglial cells
- (2017) Sharifah Syed Mortadza et al. Scientific Reports
- The Role of Microglia in Retinal Neurodegeneration: Alzheimer's Disease, Parkinson, and Glaucoma
- (2017) Ana I. Ramirez et al. Frontiers in Aging Neuroscience
- Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments
- (2017) Panchanan Maiti et al. Translational Neurodegeneration
- Inflammatory Process in Alzheimer's and Parkinson's Diseases: Central Role of Cytokines
- (2016) Qamre Alam et al. CURRENT PHARMACEUTICAL DESIGN
- Extended therapeutic window of a novel peptide inhibitor of TRPM2 channels following focal cerebral ischemia
- (2016) Takeru Shimizu et al. EXPERIMENTAL NEUROLOGY
- Microglia across the lifespan: from origin to function in brain development, plasticity and cognition
- (2016) Tuan Leng Tay et al. JOURNAL OF PHYSIOLOGY-LONDON
- TRPM2 Promotes Neurotoxin MPP+/MPTP-Induced Cell Death
- (2016) Yuyang Sun et al. MOLECULAR NEUROBIOLOGY
- Role of Microglia in Neurological Disorders and Their Potentials as a Therapeutic Target
- (2016) Li Du et al. MOLECULAR NEUROBIOLOGY
- The TRPM2 ion channel is required for sensitivity to warmth
- (2016) Chun-Hsiang Tan et al. NATURE
- The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia
- (2016) K. Song et al. SCIENCE
- Cyclic ADP-Ribose and Heat Regulate Oxytocin Release via CD38 and TRPM2 in the Hypothalamus during Social or Psychological Stress in Mice
- (2016) Jing Zhong et al. Frontiers in Neuroscience
- Innate Immune Pattern Recognition: A Cell Biological Perspective
- (2015) Sky W. Brubaker et al. Annual Review of Immunology
- Non-NMDAR neuronal Ca2+–permeable channels in delayed neuronal death and as potential therapeutic targets for ischemic brain damage
- (2015) Chaokun Li et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Redox Signal-mediated Enhancement of the Temperature Sensitivity of Transient Receptor Potential Melastatin 2 (TRPM2) Elevates Glucose-induced Insulin Secretion from Pancreatic Islets
- (2015) Makiko Kashio et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ruling out pyridine dinucleotides as true TRPM2 channel activators reveals novel direct agonist ADP-ribose-2′-phosphate
- (2015) Balázs Tóth et al. JOURNAL OF GENERAL PHYSIOLOGY
- TRPM2, a Susceptibility Gene for Bipolar Disorder, Regulates Glycogen Synthase Kinase-3 Activity in the Brain
- (2015) Y. Jang et al. JOURNAL OF NEUROSCIENCE
- The Transient Receptor Potential Melastatin 2 (TRPM2) Channel Contributes to -Amyloid Oligomer-Related Neurotoxicity and Memory Impairment
- (2015) V. G. Ostapchenko et al. JOURNAL OF NEUROSCIENCE
- Depression as a Microglial Disease
- (2015) Raz Yirmiya et al. TRENDS IN NEUROSCIENCES
- TRPM2 Channel-Mediated ROS-Sensitive Ca2+ Signaling Mechanisms in Immune Cells
- (2015) Sharifah Alawieyah Syed Mortadza et al. Frontiers in Immunology
- TRPM2 contributes to LPS/IFNγ-induced production of nitric oxide via the p38/JNK pathway in microglia
- (2014) Takahito Miyake et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Reduction in traumatic brain injury-induced oxidative stress, apoptosis, and calcium entry in rat hippocampus by melatonin: Possible involvement of TRPM2 channels
- (2014) Vehbi Yürüker et al. METABOLIC BRAIN DISEASE
- Transient Receptor Potential Melastatin Subfamily Member 2 Cation Channel Regulates Detrimental Immune Cell Invasion in Ischemic Stroke
- (2014) Mathias Gelderblom et al. STROKE
- TRPM2 channel deficiency prevents delayed cytosolic Zn2+ accumulation and CA1 pyramidal neuronal death after transient global ischemia
- (2014) M Ye et al. Cell Death & Disease
- Androgen and PARP-1 Regulation of TRPM2 Channels after Ischemic Injury
- (2013) Takeru Shimizu et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Modulation of NMDAR Subunit Expression by TRPM2 Channels Regulates Neuronal Vulnerability to Ischemic Cell Death
- (2013) I. Alim et al. JOURNAL OF NEUROSCIENCE
- Microglial Regulation of Neuropathic Pain
- (2013) Makoto Tsuda et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Microglia: New Roles for the Synaptic Stripper
- (2013) Helmut Kettenmann et al. NEURON
- The TRPM2 ion channel, an oxidative stress and metabolic sensor regulating innate immunity and inflammation
- (2012) Heather Knowles et al. IMMUNOLOGIC RESEARCH
- TRPM2 Contributes to Inflammatory and Neuropathic Pain through the Aggravation of Pronociceptive Inflammatory Responses in Mice
- (2012) K. Haraguchi et al. JOURNAL OF NEUROSCIENCE
- NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
- (2012) Michael T. Heneka et al. NATURE
- Redox signal-mediated sensitization of transient receptor potential melastatin 2 (TRPM2) to temperature affects macrophage functions
- (2012) M. Kashio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Roles of TRPM2 in oxidative stress
- (2011) Nobuaki Takahashi et al. CELL CALCIUM
- Sex Differences in Neuroprotection Provided by Inhibition of TRPM2 Channels following Experimental Stroke
- (2011) Jia Jia et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Mechanisms Underlying Inflammation in Neurodegeneration
- (2010) Christopher K. Glass et al. CELL
- Microglia Shape Adult Hippocampal Neurogenesis through Apoptosis-Coupled Phagocytosis
- (2010) Amanda Sierra et al. Cell Stem Cell
- TRPM2 channel properties, functions and therapeutic potentials
- (2010) Lin-Hua Jiang et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Depletion of GSH in glial cells induces neurotoxicity: relevance to aging and degenerative neurological diseases
- (2010) Moonhee Lee et al. FASEB JOURNAL
- Identification of Direct and Indirect Effectors of the Transient Receptor Potential Melastatin 2 (TRPM2) Cation Channel
- (2010) Balázs Tóth et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transient Receptor Potential Melastatin 2 Expression is Increased Following Experimental Traumatic Brain Injury in Rats
- (2010) Naomi L. Cook et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Neuropathic Pain: A Maladaptive Response of the Nervous System to Damage
- (2009) Michael Costigan et al. Annual Review of Neuroscience
- Lysophosphatidylcholine induces glial cell activation: Role of rho kinase
- (2009) Abdullah Md. Sheikh et al. GLIA
- Intracellular calcium activates TRPM2 and its alternative spliced isoforms
- (2009) J. Du et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SYMPOSIUM: Clearance of Aβ from the Brain in Alzheimer' Disease: The Role of the Immune System in Clearance of Aβ from the Brain
- (2008) Delphine Boche et al. BRAIN PATHOLOGY
- Identification of Pore Residues Engaged in Determining Divalent Cationic Permeation in Transient Receptor Potential Melastatin Subtype Channel 2
- (2008) Rong Xia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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