Inflammatory monocytes are detrimental to the host immune response during acute infection with Cryptococcus neoformans

Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection

(2018) Nydiaris Hernández-Santos et al.   Cell Host & Microbe

The F-Box Protein Fbp1 Shapes the Immunogenic Potential of Cryptococcus neoformans

(2018) Jorge Masso-Silva et al.   mBio

IFN-γ immune priming of macrophages in vivo induces prolonged STAT1 binding and protection against Cryptococcus neoformans

(2018) Chrissy M. Leopold Wager et al.   PLoS Pathogens

Development and differentiation of early innate lymphoid progenitors

(2017) Christelle Harly et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Different Lymphocyte Populations Direct Dichotomous Eosinophil or Neutrophil Responses to PulmonaryCryptococcusInfection

(2017) Darin L. Wiesner et al.   JOURNAL OF IMMUNOLOGY

Candida albicans Chitin Increases Arginase-1 Activity in Human Macrophages, with an Impact on Macrophage Antimicrobial Functions

(2017) Jeanette Wagener et al.   mBio

Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma

(2017) Evelyn Santos Guerra et al.   PLoS Pathogens

Arginine Metabolism in Myeloid Cells Shapes Innate and Adaptive Immunity

(2017) Paulo C. Rodriguez et al.   Frontiers in Immunology

Innate Lymphocyte/Ly6C hi Monocyte Crosstalk Promotes Klebsiella Pneumoniae Clearance

(2016) Huizhong Xiong et al.   CELL

DAP12 Inhibits Pulmonary Immune Responses to Cryptococcus neoformans

(2016) Lena J. Heung et al.   INFECTION AND IMMUNITY

The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity

(2015) Andrew L. Croxford et al.   IMMUNITY

STAT1 Signaling within Macrophages Is Required for Antifungal Activity against Cryptococcus neoformans

(2015) Chrissy M. Leopold Wager et al.   INFECTION AND IMMUNITY

Chitin Recognition via Chitotriosidase Promotes Pathologic Type-2 Helper T Cell Responses to Cryptococcal Infection

(2015) Darin L. Wiesner et al.   PLoS Pathogens

The RAG Recombinase Dictates Functional Heterogeneity and Cellular Fitness in Natural Killer Cells

(2014) Jenny M. Karo et al.   CELL

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Efficient phagocytosis and laccase activity affect the outcome of HIV-associated cryptococcosis

(2014) Wilber Sabiiti et al.   JOURNAL OF CLINICAL INVESTIGATION

Innate Antifungal Immunity of Human Eosinophils Mediated by a  2 Integrin, CD11b

(2014) J. Yoon et al.   JOURNAL OF IMMUNOLOGY

CCR2 Mediates Conventional Dendritic Cell Recruitment and the Formation of Bronchovascular Mononuclear Cell Infiltrates in the Lungs of Mice Infected with Cryptococcus neoformans

(2014) J. J. Osterholzer et al.   JOURNAL OF IMMUNOLOGY

Candida albicans Suppresses Nitric Oxide Generation from Macrophages via a Secreted Molecule

(2014) John R. Collette et al.   PLoS One

Inflammatory Monocytes Orchestrate Innate Antifungal Immunity in the Lung

(2014) Vanessa Espinosa et al.   PLoS Pathogens

Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages

(2014) Meera Rath et al.   Frontiers in Immunology

Eosinophil Deficiency Compromises Lung Defense against Aspergillus fumigatus

(2013) Lauren M. Lilly et al.   INFECTION AND IMMUNITY

Impact of Surfactant Protein D, Interleukin-5, and Eosinophilia on Cryptococcosis

(2013) Stephanie M. Holmer et al.   INFECTION AND IMMUNITY

Interleukin-17A Enhances Host Defense against Cryptococcal Lung Infection through Effects Mediated by Leukocyte Recruitment, Activation, and Gamma Interferon Production

(2013) Benjamin J. Murdock et al.   INFECTION AND IMMUNITY

Abrogation of IL-4 receptor-α-dependent alternatively activated macrophages is sufficient to confer resistance against pulmonary cryptococcosis despite an ongoing Th2 response

(2013) Uwe Müller et al.   INTERNATIONAL IMMUNOLOGY

Inflammatory Monocytes Mediate Early and Organ-Specific Innate Defense During Systemic Candidiasis

(2013) Lisa Y. Ngo et al.   JOURNAL OF INFECTIOUS DISEASES

Type 2 innate lymphoid cells control eosinophil homeostasis

(2013) Jesse C. Nussbaum et al.   NATURE

Systematic evaluation of spliced alignment programs for RNA-seq data

(2013) Pär G Engström et al.   NATURE METHODS

Combination Antifungal Therapy for Cryptococcal Meningitis

(2013) Jeremy N. Day et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of Arginase 1 from Myeloid Cells in Th2-Dominated Lung Inflammation

(2013) Luke Barron et al.   PLoS One

Macrophage M1/M2 Polarization Dynamically Adapts to Changes in Cytokine Microenvironments in Cryptococcus neoformans Infection

(2013) M. J. Davis et al.   mBio

Essential yet limited role for CCR2+ inflammatory monocytes during Mycobacterium tuberculosis-specific T cell priming

(2013) Miriam Samstein et al.   eLife

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Fungi Subvert Vaccine T Cell Priming at the Respiratory Mucosa by Preventing Chemokine-Induced Influx of Inflammatory Monocytes

(2012) Marcel Wüthrich et al.   IMMUNITY

Titan Cell Production Enhances the Virulence of Cryptococcus neoformans

(2012) Juliet N. Crabtree et al.   INFECTION AND IMMUNITY

Protective Immunity against Pulmonary Cryptococcosis Is Associated with STAT1-Mediated Classical Macrophage Activation

(2012) S. E. Hardison et al.   JOURNAL OF IMMUNOLOGY

Comparison and Temporal Trends of Three Groups with Cryptococcosis: HIV-Infected, Solid Organ Transplant, and HIV-Negative/Non-Transplant

(2012) Emily W. Bratton et al.   PLoS One

Chemokine Receptor 2-Mediated Accumulation of Fungicidal Exudate Macrophages in Mice That Clear Cryptococcal Lung Infection

(2011) John J. Osterholzer et al.   AMERICAN JOURNAL OF PATHOLOGY

Eosinophils elicit proliferation of naive and fungal-specific cells in vivo so enhancing a T helper type 1 cytokine profile in favour of a protective immune response against Cryptococcus neoformans infection

(2011) Ana P. Garro et al.   IMMUNOLOGY

Identification of Innate IL-5-Producing Cells and Their Role in Lung Eosinophil Regulation and Antitumor Immunity

(2011) M. Ikutani et al.   JOURNAL OF IMMUNOLOGY

Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function

(2011) Claire S. Whyte et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Dynamic Interplay among Monocyte-Derived, Dermal, and Resident Lymph Node Dendritic Cells during the Generation of Vaccine Immunity to Fungi

(2010) Karen Ersland et al.   Cell Host & Microbe

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Rat eosinophils stimulate the expansion of Cryptococcus neoformans-specific CD4+ and CD8+ T cells with a T-helper 1 profile

(2010) Ana P. Garro et al.   IMMUNOLOGY

Eosinophilia, meningitis and pulmonary nodules in a young woman

(2010) P. E. Pfeffer et al.   THORAX

IL-4/IL-13-Dependent Alternative Activation of Macrophages but Not Microglial Cells Is Associated with Uncontrolled Cerebral Cryptococcosis

(2009) Werner Stenzel et al.   AMERICAN JOURNAL OF PATHOLOGY

The outcome of Cryptococcus neoformans intracellular pathogenesis in human monocytes

(2009) Mauricio Alvarez et al.   BMC MICROBIOLOGY

Inflammatory Monocytes Facilitate Adaptive CD4 T Cell Responses during Respiratory Fungal Infection

(2009) Tobias M. Hohl et al.   Cell Host & Microbe

Th2 but Not Th1 Immune Bias Results in Altered Lung Functions in a Murine Model of Pulmonary Cryptococcus neoformans Infection

(2009) A. V. Jain et al.   INFECTION AND IMMUNITY

Selective Expansion of the Monocytic Lineage Directed by Bacterial Infection

(2009) N. V. Serbina et al.   JOURNAL OF IMMUNOLOGY

Accumulation of CD11b+ Lung Dendritic Cells in Response to Fungal Infection Results from the CCR2-Mediated Recruitment and Differentiation of Ly-6Chigh Monocytes

(2009) J. J. Osterholzer et al.   JOURNAL OF IMMUNOLOGY

The CCL7-CCL2-CCR2 Axis Regulates IL-4 Production in Lungs and Fungal Immunity

(2009) W. A. Szymczak et al.   JOURNAL OF IMMUNOLOGY

Alternatively Activated and Immunoregulatory Monocytes in Human Filarial Infections

(2009) Subash Babu et al.   JOURNAL OF INFECTIOUS DISEASES

Monocyte-Mediated Defense Against Microbial Pathogens

(2008) Natalya V. Serbina et al.   Annual Review of Immunology

Inheritance of Immune Polarization Patterns Is Linked to Resistance versus Susceptibility to Cryptococcus neoformans in a Mouse Model

(2008) G.-h. Chen et al.   INFECTION AND IMMUNITY

Evidence of a Role for Monocytes in Dissemination and Brain Invasion by Cryptococcus neoformans

(2008) C. Charlier et al.   INFECTION AND IMMUNITY

Disseminated cryptococcal infection with eosinophilia in a healthy person

(2008) Hiromichi Yamaguchi et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

(2008) Karim C El Kasmi et al.   NATURE IMMUNOLOGY

The Immunological Genome Project: networks of gene expression in immune cells

(2008) Tracy S P Heng et al.   NATURE IMMUNOLOGY