Chitin Recognition via Chitotriosidase Promotes Pathologic Type-2 Helper T Cell Responses to Cryptococcal Infection

CD4+FoxP3+regulatory T cells suppress fatal T helper 2 cell immunity during pulmonary fungal infection

(2014) Bianca Schulze et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Chitin Activates Parallel Immune Modules that Direct Distinct Inflammatory Responses via Innate Lymphoid Type 2 and γδ T Cells

(2014) Steven J. Van Dyken et al.   IMMUNITY

Group 2 Innate Lymphoid Cells Are Critical for the Initiation of Adaptive T Helper 2 Cell-Mediated Allergic Lung Inflammation

(2014) Timotheus Y.F. Halim et al.   IMMUNITY

Timing of Antiretroviral Therapy after Diagnosis of Cryptococcal Meningitis

(2014) David R. Boulware et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation

(2014) Jeanette Wagener et al.   PLoS Pathogens

Titan cells in Cryptococcus neoformans: cells with a giant impact

(2013) Oscar Zaragoza et al.   CURRENT OPINION IN MICROBIOLOGY

Conventional and Monocyte-Derived CD11b+ Dendritic Cells Initiate and Maintain T Helper 2 Cell-Mediated Immunity to House Dust Mite Allergen

(2013) Maud Plantinga et al.   IMMUNITY

IRF4 Transcription-Factor-Dependent CD103+CD11b+ Dendritic Cells Drive Mucosal T Helper 17 Cell Differentiation

(2013) Emma K. Persson et al.   IMMUNITY

Control of T Helper 2 Responses by Transcription Factor IRF4-Dependent Dendritic Cells

(2013) Yan Gao et al.   IMMUNITY

IRF4 Transcription Factor-Dependent CD11b+ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses

(2013) Andreas Schlitzer et al.   IMMUNITY

The Cryptococcus neoformans Rim101 Transcription Factor Directly Regulates Genes Required for Adaptation to the Host

(2013) T. R. O'Meara et al.   MOLECULAR AND CELLULAR BIOLOGY

Type 2 innate lymphoid cells control eosinophil homeostasis

(2013) Jesse C. Nussbaum et al.   NATURE

TH2, allergy and group 2 innate lymphoid cells

(2013) Paula Licona-Limón et al.   NATURE IMMUNOLOGY

A Dimorphic Fungus Causing Disseminated Infection in South Africa

(2013) Chris Kenyon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pneumocystis jirovecii Pneumonia in Tropical and Low and Middle Income Countries: A Systematic Review and Meta-Regression

(2013) David M. Lowe et al.   PLoS One

Cleavage of Fibrinogen by Proteinases Elicits Allergic Responses Through Toll-Like Receptor 4

(2013) V. O. Millien et al.   SCIENCE

An encapsulation of iron homeostasis and virulence in Cryptococcus neoformans

(2013) James W. Kronstad et al.   TRENDS IN MICROBIOLOGY

Cryptococcus neoformans Rim101 Is Associated with Cell Wall Remodeling and Evasion of the Host Immune Responses

(2013) T. R. O'Meara et al.   mBio

Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation

(2013) Jesse W. Williams et al.   Nature Communications

Innate Sensing of Chitin and Chitosan

(2013) Chelsea L. Bueter et al.   PLoS Pathogens

Adjunctive interferon-γ immunotherapy for the treatment of HIV-associated cryptococcal meningitis

(2012) Joseph N. Jarvis et al.   AIDS

Chitin Elicits CCL2 from Airway Epithelial Cells and Induces CCR2-Dependent Innate Allergic Inflammation in the Lung

(2012) R. M. Roy et al.   JOURNAL OF IMMUNOLOGY

Chitinase 1 Is a Biomarker for and Therapeutic Target in Scleroderma-Associated Interstitial Lung Disease That Augments TGF- 1 Signaling

(2012) C. G. Lee et al.   JOURNAL OF IMMUNOLOGY

Lack of IL-4 receptor expression on T helper cells reduces T helper 2 cell polyfunctionality and confers resistance in allergic bronchopulmonary mycosis

(2012) U Müller et al.   Mucosal Immunology

Chitin-Induced Dimerization Activates a Plant Immune Receptor

(2012) T. Liu et al.   SCIENCE

New Paradigms in Type 2 Immunity

(2012) B. Pulendran et al.   SCIENCE

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Cryptococcal Genotype Influences Immunologic Response and Human Clinical Outcome after Meningitis

(2012) D. L. Wiesner et al.   mBio

Acidic Mammalian Chitinase Is Not a Critical Target for Allergic Airway Disease

(2011) Lori J. Fitz et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Cryptococcal Titan Cell Formation Is Regulated by G-Protein Signaling in Response to Multiple Stimuli

(2011) Laura H. Okagaki et al.   EUKARYOTIC CELL

Fungal Chitin from Asthma-Associated Home Environments Induces Eosinophilic Lung Infiltration

(2011) S. J. Van Dyken et al.   JOURNAL OF IMMUNOLOGY

Chitin particles induce size-dependent but carbohydrate-independent innate eosinophilia

(2011) M. Kogiso et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Chitin synthesis and fungal pathogenesis

(2010) Megan D Lenardon et al.   CURRENT OPINION IN MICROBIOLOGY

Conserved natural IgM antibodies mediate innate and adaptive immunity against the opportunistic fungusPneumocystis murina

(2010) Rekha R. Rapaka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Paucity of Initial Cerebrospinal Fluid Inflammation in Cryptococcal Meningitis Is Associated with Subsequent Immune Reconstitution Inflammatory Syndrome

(2010) David R. Boulware et al.   JOURNAL OF INFECTIOUS DISEASES

Clinical Features and Serum Biomarkers in HIV Immune Reconstitution Inflammatory Syndrome after Cryptococcal Meningitis: A Prospective Cohort Study

(2010) David R. Boulware et al.   PLOS MEDICINE

Interaction of Cryptococcus neoformans Rim101 and Protein Kinase A Regulates Capsule

(2010) Teresa R. O'Meara et al.   PLoS Pathogens

Cryptococcal Cell Morphology Affects Host Cell Interactions and Pathogenicity

(2010) Laura H. Okagaki et al.   PLoS Pathogens

Fungal Cell Gigantism during Mammalian Infection

(2010) Oscar Zaragoza et al.   PLoS Pathogens

Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS

(2009) Benjamin J Park et al.   AIDS

Chitotriosidase and gene therapy for fungal infections

(2009) C. Gordon-Thomson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Chitinases and chitinase-like proteins: potential therapeutic targets for the treatment of T-helper type 2 allergies

(2009) T. E. Sutherland et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Penicillium marneffei infection in HIV

(2009) Andrew P Ustianowski et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Th2 but Not Th1 Immune Bias Results in Altered Lung Functions in a Murine Model of Pulmonary Cryptococcus neoformans Infection

(2009) A. V. Jain et al.   INFECTION AND IMMUNITY

In vivo expansion of T reg cells with IL-2–mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression

(2009) Kylie E. Webster et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Feedback control of regulatory T cell homeostasis by dendritic cells in vivo

(2009) Guillaume Darrasse-Jèze et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chitin Is a Size-Dependent Regulator of Macrophage TNF and IL-10 Production

(2009) C. A. Da Silva et al.   JOURNAL OF IMMUNOLOGY

Tracking epitope-specific T cells

(2009) James J Moon et al.   Nature Protocols

Characterization of Receptor Proteins using Affinity Cross-linking with Biotinylated Ligands

(2009) Tomonori Shinya et al.   PLANT AND CELL PHYSIOLOGY

Chitin regulation of immune responses: an old molecule with new roles

(2008) Chun Geun Lee et al.   CURRENT OPINION IN IMMUNOLOGY

Division of labor between dendritic cell subsets of the lung

(2008) C H GeurtsvanKessel et al.   Mucosal Immunology

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

(2008) K. Hildner et al.   SCIENCE