A Computational Model of Loss of Dopaminergic Cells in Parkinson's Disease Due to Glutamate-Induced Excitotoxicity

Nitration of microtubules blocks axonal mitochondrial transport in a human pluripotent stem cell model of Parkinson’s disease

(2018) Morgan G. Stykel et al.   FASEB JOURNAL

PINK1 Phosphorylates MIC60/Mitofilin to Control Structural Plasticity of Mitochondrial Crista Junctions

(2018) Pei-I Tsai et al.   MOLECULAR CELL

On Cell Loss and Selective Vulnerability of Neuronal Populations in Parkinson's Disease

(2018) Nicolas Giguère et al.   Frontiers in Neurology

Selective neuronal vulnerability in Parkinson disease

(2017) D. James Surmeier et al.   NATURE REVIEWS NEUROSCIENCE

The Role of Astrocyte Dysfunction in Parkinson’s Disease Pathogenesis

(2017) Heather D.E. Booth et al.   TRENDS IN NEUROSCIENCES

Computational Model of Recurrent Subthalamo-Pallidal Circuit for Generation of Parkinsonian Oscillations

(2017) Osamu Shouno et al.   Frontiers in Neuroanatomy

Revisiting the Medical Management of Parkinson's Disease: Levodopa versus Dopamine Agonist

(2016) Jinglin Zhang et al.   Current Neuropharmacology

The external globus pallidus: progress and perspectives

(2016) Daniel J. Hegeman et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Probing the Role of Medication, DBS Electrode Position, and Antidromic Activation on Impulsivity Using a Computational Model of Basal Ganglia

(2016) Alekhya Mandali et al.   Frontiers in Human Neuroscience

Twenty years of ModelDB and beyond: building essential modeling tools for the future of neuroscience

(2016) Robert A. McDougal et al.   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

Subtalamotomía como neuroprotección en la enfermedad de Parkinson. El papel de los ultrasonidos guiados por resonancia como cirugía temprana

(2016) Jorge Guridi et al.   NEUROCIRUGIA

D2 dopamine receptors modulate neuronal resonance in subthalamic nucleus and cortical high-voltage spindles through HCN channels

(2016) Chen Yang et al.   NEUROPHARMACOLOGY

Vascular Dynamics Aid a Coupled Neurovascular Network Learn Sparse Independent Features: A Computational Model

(2016) Ryan T. Philips et al.   Frontiers in Neural Circuits

Low-Dimensional Models of “Neuro-Glio-Vascular Unit” for Describing Neural Dynamics under Normal and Energy-Starved Conditions

(2016) Karishma Chhabria et al.   Frontiers in Neurology

Selective blockade of mGlu5 metabotropic glutamate receptors is protective against hepatic mitochondrial dysfunction in 6-OHDA lesioned Parkinsonian rats

(2015) Andrea Ferrigno et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Elevated Mitochondrial Bioenergetics and Axonal Arborization Size Are Key Contributors to the Vulnerability of Dopamine Neurons

(2015) Consiglia Pacelli et al.   CURRENT BIOLOGY

Integrated dopaminergic neuronal model with reduced intracellular processes and inhibitory autoreceptors

(2015) Maell Cullen et al.   IET Systems Biology

Dual target strategy: combining distinct non-dopaminergic treatments reduces neuronal cell loss and synergistically modulatesl-DOPA-induced rotational behavior in a rodent model of Parkinson's disease

(2015) Marie-Therese Fuzzati-Armentero et al.   JOURNAL OF NEUROCHEMISTRY

Letter to the Editor: Parkinson's disease and early subthalamotomy

(2015) Jorge Guridi et al.   JOURNAL OF NEUROSURGERY

Mechanism of Deep Brain Stimulation

(2015) Satomi Chiken et al.   NEUROSCIENTIST

Computational Models Describing Possible Mechanisms for Generation of Excessive Beta Oscillations in Parkinson’s Disease

(2015) Alex Pavlides et al.   PLoS Computational Biology

A spiking Basal Ganglia model of synchrony, exploration and decision making

(2015) Alekhya Mandali et al.   Frontiers in Neuroscience

Dopaminergic Control of the Globus Pallidus through Activation of D2 Receptors and Its Impact on the Electrical Activity of Subthalamic Nucleus and Substantia Nigra Reticulata Neurons

(2015) Omar Mamad et al.   PLoS One

Deep Brain Stimulation: Are Astrocytes a Key Driver Behind the Scene?

(2014) Albert J. Fenoy et al.   CNS Neuroscience & Therapeutics

The role of D2-autoreceptors in regulating dopamine neuron activity and transmission

(2014) C.P. Ford   NEUROSCIENCE

Coordinated reset stimulation in a large-scale model of the STN-GPe circuit

(2014) Martin Ebert et al.   Frontiers in Computational Neuroscience

Effects of antidromic and orthodromic activation of STN afferent axons during DBS in Parkinson's disease: a simulation study

(2014) Guiyeom Kang et al.   Frontiers in Computational Neuroscience

NeuroElectro: a window to the world's neuron electrophysiology data

(2014) Shreejoy J. Tripathy et al.   Frontiers in Neuroinformatics

Interaction of Oscillations, and Their Suppression via Deep Brain Stimulation, in a Model of the Cortico-Basal Ganglia Network

(2013) Guiyeom Kang et al.   IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING

A further update on the role of excitotoxicity in the pathogenesis of Parkinson’s disease

(2013) Giulia Ambrosi et al.   JOURNAL OF NEURAL TRANSMISSION

Subthalamotomy in the treatment of Parkinson's disease: clinical aspects and mechanisms of action

(2013) Vincent A. Jourdain et al.   JOURNAL OF NEUROSURGERY

Axonal and synaptic failure suppress the transfer of firing rate oscillations, synchrony and information during high frequency deep brain stimulation

(2013) Robert Rosenbaum et al.   NEUROBIOLOGY OF DISEASE

Sugar for the brain: the role of glucose in physiological and pathological brain function

(2013) Philipp Mergenthaler et al.   TRENDS IN NEUROSCIENCES

Signal enhancement in the output stage of the basal ganglia by synaptic short-term plasticity in the direct, indirect, and hyperdirect pathways

(2013) Mikael Lindahl et al.   Frontiers in Computational Neuroscience

The energy cost of action potential propagation in dopamine neurons: clues to susceptibility in Parkinson's disease

(2013) Eleftheria K. Pissadaki et al.   Frontiers in Computational Neuroscience

Dopamine protects neurons against glutamate-induced excitotoxicity

(2013) A Vaarmann et al.   Cell Death & Disease

Role of Oxidative Stress in Parkinson's Disease

(2013) Onyou Hwang   Experimental Neurobiology

Allosteric modulation of the group III mGlu4 receptor provides functional neuroprotection in the 6-hydroxydopamine rat model of Parkinson's disease

(2012) Matthew J Betts et al.   BRITISH JOURNAL OF PHARMACOLOGY

Proliferation of External Globus Pallidus-Subthalamic Nucleus Synapses following Degeneration of Midbrain Dopamine Neurons

(2012) K. Y. Fan et al.   JOURNAL OF NEUROSCIENCE

Species Differences in Somatodendritic Dopamine Transmission Determine D2-Autoreceptor-Mediated Inhibition of Ventral Tegmental Area Neuron Firing

(2012) N. A. Courtney et al.   JOURNAL OF NEUROSCIENCE

Neuronal vulnerability, pathogenesis, and Parkinson's disease

(2012) David Sulzer et al.   MOVEMENT DISORDERS

Living on the edge with too many mouths to feed: Why dopamine neurons die

(2012) J. Paul Bolam et al.   MOVEMENT DISORDERS

Astrocyte-derived GDNF is a potent inhibitor of microglial activation

(2012) Sandra Moreira Rocha et al.   NEUROBIOLOGY OF DISEASE

Blockade of metabotropic glutamate receptors inhibits cognition and neurodegeneration in an MPTP-induced Parkinson's disease rat model

(2012) Ming-Hong Hsieh et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

On the Origin of Tremor in Parkinson’s Disease

(2012) Andrey Dovzhenok et al.   PLoS One

A Computational Model of Neuro-Glio-Vascular Loop Interactions

(2012) Bankim Subhash Chander et al.   PLoS One

Metabotropic glutamate receptor 5 antagonist protects dopaminergic and noradrenergic neurons from degeneration in MPTP-treated monkeys

(2011) G. J. Masilamoni et al.   BRAIN

Dopamine deficiency increases synchronized activity in the rat subthalamic nucleus

(2011) Alessandra Lintas et al.   BRAIN RESEARCH

A continuous high frequency stimulation of the subthalamic nucleus determines a suppression of excitatory synaptic transmission in nigral dopaminergic neurons recorded in vitro

(2011) Ada Ledonne et al.   EXPERIMENTAL NEUROLOGY

Axonal failure during high frequency stimulation of rat subthalamic nucleus

(2011) Fang Zheng et al.   JOURNAL OF PHYSIOLOGY-LONDON

Decoupling neuronal oscillations during subthalamic nucleus stimulation in the parkinsonian primate

(2011) A. Moran et al.   NEUROBIOLOGY OF DISEASE

Neural dynamics in Parkinsonian brain: The boundary between synchronized and nonsynchronized dynamics

(2011) Choongseok Park et al.   PHYSICAL REVIEW E

The Promise of Neuroprotective Agents in Parkinson?s Disease

(2011) Stacey E. Seidl et al.   Frontiers in Neurology

Resting oscillatory cortico-subthalamic connectivity in patients with Parkinson’s disease

(2010) Vladimir Litvak et al.   BRAIN

Symptomatic and neuroprotective effects following activation of nigral group III metabotropic glutamate receptors in rodent models of Parkinson's disease

(2010) PJ Austin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

Systems of Biology and the Spirit of Tustin [Perspectives]

(2010)   IEEE CONTROL SYSTEMS MAGAZINE

Evaluation of novel stimulus waveforms for deep brain stimulation

(2010) Thomas J Foutz et al.   Journal of Neural Engineering

Regulation of dopaminergic neuron firing by heterogeneous dopamine autoreceptors in the substantia nigra pars compacta

(2010) Jin Young Jang et al.   JOURNAL OF NEUROCHEMISTRY

Fine Temporal Structure of Beta Oscillations Synchronization in Subthalamic Nucleus in Parkinson's Disease

(2010) Choongseok Park et al.   JOURNAL OF NEUROPHYSIOLOGY

Stimulation of the rat subthalamic nucleus is neuroprotective following significant nigral dopamine neuron loss

(2010) A.L. Spieles-Engemann et al.   NEUROBIOLOGY OF DISEASE

An energy systems approach to Parkinson's disease

(2010) Peter Wellstead et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Regulation of astrocyte inflammatory responses by the Parkinson’s disease-associated gene DJ-1

(2009) Jens Waak et al.   FASEB JOURNAL

Therapeutic efficacy of unilateral subthalamotomy in Parkinson's disease: results in 89 patients followed for up to 36 months

(2009) L Alvarez et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

A Model of Indispensability of a Large Glial Layer in Cerebrovascular Circulation

(2009) Rohit Gandrakota et al.   NEURAL COMPUTATION

Interplay between Cytosolic Dopamine, Calcium, and α-Synuclein Causes Selective Death of Substantia Nigra Neurons

(2009) Eugene V. Mosharov et al.   NEURON

Neuromelanin Activates Microglia and Induces Degeneration of Dopaminergic Neurons: Implications for Progression of Parkinson’s Disease

(2009) Wei Zhang et al.   NEUROTOXICITY RESEARCH

Human neuromelanin induces neuroinflammation and neurodegeneration in the rat substantia nigra: implications for Parkinson's disease

(2008) Luigi Zecca et al.   ACTA NEUROPATHOLOGICA

Neural Stimulation and Recording Electrodes

(2008) Stuart F. Cogan   Annual Review of Biomedical Engineering

EMERGENCE OF PREFERRED FIRING SEQUENCES IN LARGE SPIKING NEURAL NETWORKS DURING SIMULATED NEURONAL DEVELOPMENT

(2008) JAVIER IGLESIAS et al.   International Journal of Neural Systems

Rebound bursts following inhibition: how dopamine modifies firing pattern in subthalamic neurons

(2008) Steven W. Johnson   JOURNAL OF PHYSIOLOGY-LONDON

Latest view on the mechanism of action of deep brain stimulation

(2008) Constance Hammond et al.   MOVEMENT DISORDERS

Creatine and Its Potential Therapeutic Value for Targeting Cellular Energy Impairment in Neurodegenerative Diseases

(2008) Peter J. Adhihetty et al.   NEUROMOLECULAR MEDICINE

Glial Cells as Players in Parkinsonism: The “Good,” the “Bad,” and the “Mysterious” Glia

(2008) Maria A. Mena et al.   NEUROSCIENTIST

Complex EPSCs evoked in substantia nigra reticulata neurons are disrupted by repetitive stimulation of the subthalamic nucleus

(2008) Ke-Zhong Shen et al.   SYNAPSE

Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis

(2008) Claire Henchcliffe et al.   Nature clinical practice. Neurology

Inflammation as a causative factor in the aetiology of Parkinson's disease

(2007) P S Whitton   BRITISH JOURNAL OF PHARMACOLOGY

Glial reactions in Parkinson's disease

(2007) Patrick L. McGeer et al.   MOVEMENT DISORDERS

Mechanisms of action of deep brain stimulation (DBS)

(2007) Erwin B. Montgomery et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS