标题
Selective neuronal vulnerability in Parkinson disease
作者
关键词
-
出版物
NATURE REVIEWS NEUROSCIENCE
Volume 18, Issue 2, Pages 101-113
出版商
Springer Nature
发表日期
2017-01-20
DOI
10.1038/nrn.2016.178
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Lysosomal cell death mechanisms in aging
- (2016) Raquel Gómez-Sintes et al. AGEING RESEARCH REVIEWS
- Locus coeruleus: From global projection system to adaptive regulation of behavior
- (2016) G. Aston-Jones et al. BRAIN RESEARCH
- Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson’s disease
- (2016) Nolwen L. Rey et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Converging roles of ion channels, calcium, metabolic stress, and activity pattern ofSubstantia nigradopaminergic neurons in health and Parkinson's disease
- (2016) Johanna Duda et al. JOURNAL OF NEUROCHEMISTRY
- Differential Somatic Ca2+ Channel Profile in Midbrain Dopaminergic Neurons
- (2016) F. Philippart et al. JOURNAL OF NEUROSCIENCE
- A critical appraisal of the pathogenic protein spread hypothesis of neurodegeneration
- (2016) Dominic M. Walsh et al. NATURE REVIEWS NEUROSCIENCE
- Mitochondrial dysfunction associated with glucocerebrosidase deficiency
- (2016) Matthew E. Gegg et al. NEUROBIOLOGY OF DISEASE
- Nimodipine, an L-type calcium channel blocker attenuates mitochondrial dysfunctions to protect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice
- (2016) Alpana Singh et al. NEUROCHEMISTRY INTERNATIONAL
- Autosomal dominant Parkinson's disease caused by SNCA duplications
- (2016) Takuya Konno et al. PARKINSONISM & RELATED DISORDERS
- Brain–heart interactions: physiology and clinical implications
- (2016) Alessandro Silvani et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
- Pathological -synuclein transmission initiated by binding lymphocyte-activation gene 3
- (2016) X. Mao et al. SCIENCE
- Propagation of alpha-synuclein pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies
- (2015) Toshiki Uchihara et al. ACTA NEUROPATHOLOGICA
- Nucleus basalis of Meynert revisited: anatomy, history and differential involvement in Alzheimer’s and Parkinson’s disease
- (2015) Alan King Lun Liu et al. ACTA NEUROPATHOLOGICA
- Brain propagation of transduced α-synuclein involves non-fibrillar protein species and is enhanced in α-synuclein null mice
- (2015) Michael Helwig et al. BRAIN
- The genetics of Parkinson's disease
- (2015) Stephen Mullin et al. BRITISH MEDICAL BULLETIN
- Elevated Mitochondrial Bioenergetics and Axonal Arborization Size Are Key Contributors to the Vulnerability of Dopamine Neurons
- (2015) Consiglia Pacelli et al. CURRENT BIOLOGY
- LRRK2 Pathways Leading to Neurodegeneration
- (2015) Mark R. Cookson Current Neurology and Neuroscience Reports
- α-Synuclein and Lewy pathology in Parkinsonʼs disease
- (2015) Lorraine V. Kalia et al. CURRENT OPINION IN NEUROLOGY
- -synuclein assemblies sequester neuronal 3-Na+/K+-ATPase and impair Na+ gradient
- (2015) A. N. Shrivastava et al. EMBO JOURNAL
- Pathways to Parkinsonism Redux: convergent pathobiological mechanisms in genetics of Parkinson's disease
- (2015) Ravindran Kumaran et al. HUMAN MOLECULAR GENETICS
- Genes associated with Parkinson's disease: regulation of autophagy and beyond
- (2015) Alexandra Beilina et al. JOURNAL OF NEUROCHEMISTRY
- Gating of dopamine transmission by calcium and axonal N-, Q-, T- and L-type voltage-gated calcium channels differs between striatal domains
- (2015) Katherine R. Brimblecombe et al. JOURNAL OF PHYSIOLOGY-LONDON
- A new role for α-synuclein in Parkinson's disease: Alteration of ER-mitochondrial communication
- (2015) Cristina Guardia-Laguarta et al. MOVEMENT DISORDERS
- Viral-genetic tracing of the input–output organization of a central noradrenaline circuit
- (2015) Lindsay A. Schwarz et al. NATURE
- α-Synuclein strains cause distinct synucleinopathies after local and systemic administration
- (2015) W. Peelaerts et al. NATURE
- Identification of neurodegenerative factors using translatome–regulatory network analysis
- (2015) Lars Brichta et al. NATURE NEUROSCIENCE
- Dopamine midbrain neurons in health and Parkinson’s disease: Emerging roles of voltage-gated calcium channels and ATP-sensitive potassium channels
- (2015) E. Dragicevic et al. NEUROSCIENCE
- Roles of the orexin system in central motor control
- (2015) Bo Hu et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease
- (2015) Brent J. Ryan et al. TRENDS IN BIOCHEMICAL SCIENCES
- Impaired intracellular trafficking defines early Parkinson's disease
- (2015) Benjamin H.M. Hunn et al. TRENDS IN NEUROSCIENCES
- Novel subcellular localization for α-synuclein: possible functional consequences
- (2015) Cristina Guardia-Laguarta et al. Frontiers in Neuroanatomy
- Clinical Correlations With Lewy Body Pathology inLRRK2-Related Parkinson Disease
- (2015) Lorraine V. Kalia et al. JAMA Neurology
- Ageing and Parkinson's disease: Why is advancing age the biggest risk factor?
- (2014) Amy Reeve et al. AGEING RESEARCH REVIEWS
- Neuronal calcium signaling: function and dysfunction
- (2014) Marisa Brini et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Autophagy and human disease: emerging themes
- (2014) Jaime L Schneider et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- LRRK2, a puzzling protein: Insights into Parkinson's disease pathogenesis
- (2014) A. Raquel Esteves et al. EXPERIMENTAL NEUROLOGY
- Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic mice
- (2014) Meike Diepenbroek et al. HUMAN MOLECULAR GENETICS
- Soluble, Prefibrillar α-Synuclein Oligomers Promote Complex I-dependent, Ca2+-induced Mitochondrial Dysfunction
- (2014) Eric S. Luth et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- LRRK2 pathobiology in Parkinson's disease
- (2014) Ian Martin et al. JOURNAL OF NEUROCHEMISTRY
- Mutant α-Synuclein Enhances Firing Frequencies in Dopamine Substantia Nigra Neurons by Oxidative Impairment of A-Type Potassium Channels
- (2014) Mahalakshmi Subramaniam et al. JOURNAL OF NEUROSCIENCE
- Stage-dependent nigral neuronal loss in incidental Lewy body and Parkinson's disease
- (2014) Anke A. Dijkstra et al. MOVEMENT DISORDERS
- Time to redefine PD? Introductory statement of the MDS Task Force on the definition of Parkinson's disease
- (2014) Daniela Berg et al. MOVEMENT DISORDERS
- Mitochondrial oxidant stress in locus coeruleus is regulated by activity and nitric oxide synthase
- (2014) Javier Sanchez-Padilla et al. NATURE NEUROSCIENCE
- Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite–like aggregates
- (2014) Laura A Volpicelli-Daley et al. Nature Protocols
- Antihypertensive Agents and Risk of Parkinson's Disease: A Nationwide Cohort Study
- (2014) Yen-Chieh Lee et al. PLoS One
- Calcineurin determines toxic versus beneficial responses to -synuclein
- (2014) G. Caraveo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Organization of Monosynaptic Inputs to the Serotonin and Dopamine Neuromodulatory Systems
- (2014) Sachie K. Ogawa et al. Cell Reports
- Defining Midbrain Dopaminergic Neuron Diversity by Single-Cell Gene Expression Profiling
- (2014) Jean-Francois Poulin et al. Cell Reports
- Genetics and genomics of Parkinson’s disease
- (2014) Michelle K Lin et al. Genome Medicine
- Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys
- (2013) Ariadna Recasens et al. ANNALS OF NEUROLOGY
- Prion-like spreading of pathological α-synuclein in brain
- (2013) Masami Masuda-Suzukake et al. BRAIN
- Parkinson’s disease is associated with altered expression of CaV1 channels and calcium-binding proteins
- (2013) Michael J. Hurley et al. BRAIN
- Chaperone-mediated autophagy: roles in disease and aging
- (2013) Ana Maria Cuervo et al. CELL RESEARCH
- Control of arousal by the orexin neurons
- (2013) Chloe Alexandre et al. CURRENT OPINION IN NEUROBIOLOGY
- Caudo-rostral brain spreading of α-synuclein through vagal connections
- (2013) Ayse Ulusoy et al. EMBO Molecular Medicine
- Calcium Entry and -Synuclein Inclusions Elevate Dendritic Mitochondrial Oxidant Stress in Dopaminergic Neurons
- (2013) D. I. Dryanovski et al. JOURNAL OF NEUROSCIENCE
- Neuronal vulnerability, pathogenesis, and Parkinson's disease
- (2013) David Sulzer et al. MOVEMENT DISORDERS
- Parkinson's Disease and Alpha Synuclein: Is Parkinson's Disease a Prion-Like Disorder?
- (2013) C. Warren Olanow et al. MOVEMENT DISORDERS
- Deregulation of calcium homeostasis mediates secreted α–synuclein-induced neurotoxicity
- (2013) Katerina Melachroinou et al. NEUROBIOLOGY OF AGING
- Review: The future of cell therapies and brain repair: Parkinson's disease leads the way
- (2013) G. H. Petit et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- The energy cost of action potential propagation in dopamine neurons: clues to susceptibility in Parkinson's disease
- (2013) Eleftheria K. Pissadaki et al. Frontiers in Computational Neuroscience
- Physiological Phenotype and Vulnerability in Parkinson's Disease
- (2013) D. J. Surmeier et al. Cold Spring Harbor Perspectives in Medicine
- Parkin Disease
- (2013) Karen M. Doherty et al. JAMA Neurology
- Use of Calcium Channel Blockers and Parkinson’s Disease
- (2012) Björn Pasternak et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Evaluation of the Braak hypothesis: how far can it explain the pathogenesis of Parkinson's disease?
- (2012) Glenda Halliday et al. Expert Review of Neurotherapeutics
- α-Synuclein Controls Mitochondrial Calcium Homeostasis by Enhancing Endoplasmic Reticulum-Mitochondria Interactions
- (2012) Tito Calì et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitophagy and Parkinson's disease: Be eaten to stay healthy
- (2012) Rosa L.A. de Vries et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Living on the edge with too many mouths to feed: Why dopamine neurons die
- (2012) J. Paul Bolam et al. MOVEMENT DISORDERS
- The neuropathology of genetic Parkinson's disease
- (2012) Markos Poulopoulos et al. MOVEMENT DISORDERS
- Observatories of the mind
- (2012) Christof Koch et al. NATURE
- Calcium entry induces mitochondrial oxidant stress in vagal neurons at risk in Parkinson's disease
- (2012) Joshua A Goldberg et al. NATURE NEUROSCIENCE
- Axis of ageing: telomeres, p53 and mitochondria
- (2012) Ergün Sahin et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- 100 years of Lewy pathology
- (2012) Michel Goedert et al. Nature Reviews Neurology
- Lewy pathology is not the first sign of degeneration in vulnerable neurons in Parkinson disease
- (2012) J. M. Milber et al. NEUROLOGY
- Orienting and Reorienting: The Locus Coeruleus Mediates Cognition through Arousal
- (2012) Susan J. Sara et al. NEURON
- Whole-Brain Mapping of Direct Inputs to Midbrain Dopamine Neurons
- (2012) Mitsuko Watabe-Uchida et al. NEURON
- Pathological -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
- (2012) K. C. Luk et al. SCIENCE
- Origins of arousal: roles for medullary reticular neurons
- (2012) Donald W. Pfaff et al. TRENDS IN NEUROSCIENCES
- Dihydropyridine calcium channel blockers and the progression of parkinsonism
- (2011) Connie Marras et al. ANNALS OF NEUROLOGY
- Modulation of Striatal Projection Systems by Dopamine
- (2011) Charles R. Gerfen et al. Annual Review of Neuroscience
- Mitochondrial Quality Control and Dynamics in Parkinson's Disease
- (2011) Melissa K. McCoy et al. ANTIOXIDANTS & REDOX SIGNALING
- Imaging the default mode network in aging and dementia
- (2011) Anne Hafkemeijer et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Striatal β-amyloid in dementia with Lewy bodies but not Parkinson’s disease
- (2011) Glenda M. Halliday et al. JOURNAL OF NEURAL TRANSMISSION
- Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates
- (2011) Timothy J. Collier et al. NATURE REVIEWS NEUROSCIENCE
- The L-type channel antagonist isradipine is neuroprotective in a mouse model of Parkinson's disease
- (2011) E. Ilijic et al. NEUROBIOLOGY OF DISEASE
- Development of the vagal innervation of the gut: steering the wandering nerve
- (2011) E. M. Ratcliffe et al. NEUROGASTROENTEROLOGY AND MOTILITY
- Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
- (2011) Laura A. Volpicelli-Daley et al. NEURON
- Dopamine signaling as a neural correlate of consciousness
- (2011) R.D. Palmiter NEUROSCIENCE
- Social fearfulness in the human brain
- (2011) Vladimir Miskovic et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Autosomal recessive parkinsonism
- (2011) Vincenzo Bonifati PARKINSONISM & RELATED DISORDERS
- Topographical Organization of the Pedunculopontine Nucleus
- (2011) Cristina Martinez-Gonzalez et al. Frontiers in Neuroanatomy
- Cell type specific sequestration of choline acetyltransferase and tyrosine hydroxylase within Lewy bodies
- (2010) Brittany N. Dugger et al. ACTA NEUROPATHOLOGICA
- What causes cell death in Parkinson's disease?
- (2010) Amitabh Gupta et al. ANNALS OF NEUROLOGY
- Pacemaking in Dopaminergic Ventral Tegmental Area Neurons: Depolarizing Drive from Background and Voltage-Dependent Sodium Conductances
- (2010) Z. M. Khaliq et al. JOURNAL OF NEUROSCIENCE
- Raised calcium promotes α-synuclein aggregate formation
- (2010) S. Nath et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease
- (2010) Jia-Yi Li et al. MOVEMENT DISORDERS
- Brain stem pathology in Parkinson's disease: An evaluation of the Braak staging model
- (2010) Ann E. Kingsbury et al. MOVEMENT DISORDERS
- Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1
- (2010) Jaime N. Guzman et al. NATURE
- Autophagy gone awry in neurodegenerative diseases
- (2010) Esther Wong et al. NATURE NEUROSCIENCE
- Global aging and the brain
- (2010) Thomas BL Kirkwood NUTRITION REVIEWS
- Monosynaptic circuit tracing in vivo through Cre-dependent targeting and complementation of modified rabies virus
- (2010) N. R. Wall et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Unified staging system for Lewy body disorders: correlation with nigrostriatal degeneration, cognitive impairment and motor dysfunction
- (2009) Thomas G. Beach et al. ACTA NEUROPATHOLOGICA
- The role of Ca2+ signaling in the coordination of mitochondrial ATP production with cardiac work
- (2009) Robert S. Balaban BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Multifaceted deaths orchestrated by mitochondria in neurones
- (2009) Phillip Nagley et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Formation and development of Lewy pathology: a critical update
- (2009) Kurt A. Jellinger JOURNAL OF NEUROLOGY
- Sparse but Selective and Potent Synaptic Transmission From the Globus Pallidus to the Subthalamic Nucleus
- (2009) Jérôme Baufreton et al. JOURNAL OF NEUROPHYSIOLOGY
- Endogenous Calcium Buffering Capacity of Substantia Nigral Dopamine Neurons
- (2009) R. C. Foehring et al. JOURNAL OF NEUROPHYSIOLOGY
- Robust Pacemaking in Substantia Nigra Dopaminergic Neurons
- (2009) J. N. Guzman et al. JOURNAL OF NEUROSCIENCE
- Cav1.3 Channel Voltage Dependence, Not Ca2+ Selectivity, Drives Pacemaker Activity and Amplifies Bursts in Nigral Dopamine Neurons
- (2009) I. Putzier et al. JOURNAL OF NEUROSCIENCE
- Single Nigrostriatal Dopaminergic Neurons Form Widely Spread and Highly Dense Axonal Arborizations in the Neostriatum
- (2009) W. Matsuda et al. JOURNAL OF NEUROSCIENCE
- α-Synuclein and neuronal cell death
- (2009) Mark R Cookson Molecular Neurodegeneration
- Interplay between Cytosolic Dopamine, Calcium, and α-Synuclein Causes Selective Death of Substantia Nigra Neurons
- (2009) Eugene V. Mosharov et al. NEURON
- MAM: more than just a housekeeper
- (2009) Teruo Hayashi et al. TRENDS IN CELL BIOLOGY
- The progression of pathology in longitudinally followed patients with Parkinson’s disease
- (2008) Glenda Halliday et al. ACTA NEUROPATHOLOGICA
- A critical evaluation of current staging of α-synuclein pathology in Lewy body disorders
- (2008) Kurt A. Jellinger BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Dopaminergic midbrain neurons are the prime target for mitochondrial DNA deletions
- (2008) A. Bender et al. JOURNAL OF NEUROLOGY
- Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years
- (2008) Ivar Mendez et al. NATURE MEDICINE
- Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
- (2008) Jia-Yi Li et al. NATURE MEDICINE
- Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease
- (2008) Jeffrey H Kordower et al. NATURE MEDICINE
- Use of antihypertensives and the risk of Parkinson disease
- (2008) C. Becker et al. NEUROLOGY
- The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease: a critical analysis of α-synuclein staging
- (2008) M. E. Kalaitzakis et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Individual dopamine midbrain neurons: Functional diversity and flexibility in health and disease
- (2007) Birgit Liss et al. BRAIN RESEARCH REVIEWS
- ΔΨm-Dependent and -independent production of reactive oxygen species by rat brain mitochondria
- (2003) Tatyana V. Votyakova et al. JOURNAL OF NEUROCHEMISTRY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started