Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS–STING signalling
出版年份 2019 全文链接
标题
Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS–STING signalling
作者
关键词
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出版物
NATURE
Volume 566, Issue 7743, Pages 259-263
出版商
Springer Nature
发表日期
2019-02-07
DOI
10.1038/s41586-019-0928-6
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Structure of the Human cGAS–DNA Complex Reveals Enhanced Control of Immune Surveillance
- (2018) Wen Zhou et al. CELL
- Inflammation-Induced, STING-Dependent Autophagy Restricts Zika Virus Infection in the Drosophila Brain
- (2018) Yuan Liu et al. Cell Host & Microbe
- Virulent Poxviruses Inhibit DNA Sensing by Preventing STING Activation
- (2018) Iliana Georgana et al. JOURNAL OF VIROLOGY
- Biodiversity, Evolution and Ecological Specialization of Baculoviruses: A Treasure Trove for Future Applied Research
- (2018) Julien Thézé et al. Viruses-Basel
- Analysis of Drosophila STING Reveals an Evolutionarily Conserved Antimicrobial Function
- (2018) Marina Martin et al. Cell Reports
- The cGas–Sting Signaling Pathway Is Required for the Innate Immune Response Against Ectromelia Virus
- (2018) Wen-Yu Cheng et al. Frontiers in Immunology
- Poxviruses Evade Cytosolic Sensing through Disruption of an mTORC1-mTORC2 Regulatory Circuit
- (2018) Nathan Meade et al. CELL
- Complete genome sequence of a novel sea otterpox virus
- (2018) Jessica M. Jacob et al. VIRUS GENES
- Deletion of the Vaccinia Virus B1 Kinase Reveals Essential Functions of This Enzyme Complemented Partly by the Homologous Cellular Kinase VRK2
- (2017) Annabel T. Olson et al. JOURNAL OF VIROLOGY
- Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism
- (2017) Youdong Pan et al. NATURE
- Two novel poxviruses with unusual genome rearrangements: NY_014 and Murmansk
- (2017) Chad Smithson et al. VIRUS GENES
- The cGAS-STING Defense Pathway and Its Counteraction by Viruses
- (2016) Zhe Ma et al. Cell Host & Microbe
- Dali server update
- (2016) Liisa Holm et al. NUCLEIC ACIDS RESEARCH
- Replicating poxviruses for human cancer therapy
- (2015) Manbok Kim JOURNAL OF MICROBIOLOGY
- Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2′,3′ cGAMP Signaling
- (2015) Philip J. Kranzusch et al. MOLECULAR CELL
- eIF3 targets cell-proliferation messenger RNAs for translational activation or repression
- (2015) Amy S. Y. Lee et al. NATURE
- Molecular basis for the specific recognition of the metazoan cyclic GMP-AMP by the innate immune adaptor protein STING
- (2015) Heping Shi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection
- (2015) Megan H. Orzalli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Viruses transfer the antiviral second messenger cGAMP between cells
- (2015) A. Bridgeman et al. SCIENCE
- Transmission of innate immune signaling by packaging of cGAMP in viral particles
- (2015) Matteo Gentili et al. SCIENCE
- Cloak and Dagger: Alternative Immune Evasion and Modulation Strategies of Poxviruses
- (2015) Susanna Bidgood et al. Viruses-Basel
- Gene Acquisition Convergence between Entomopoxviruses and Baculoviruses
- (2015) Julien Thézé et al. Viruses-Basel
- Structure determination of Murine Norovirus NS6 proteases with C-terminal extensions designed to probe protease–substrate interactions
- (2015) Humberto Fernandes et al. PeerJ
- Innate Immune Sensing and Signaling of Cytosolic Nucleic Acids
- (2014) Jiaxi Wu et al. Annual Review of Immunology
- Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity
- (2014) Philip J. Kranzusch et al. CELL
- Hydrolysis of 2′3′-cGAMP by ENPP1 and design of nonhydrolyzable analogs
- (2014) Lingyin Li et al. Nature Chemical Biology
- Modified Vaccinia Virus Ankara Triggers Type I IFN Production in Murine Conventional Dendritic Cells via a cGAS/STING-Mediated Cytosolic DNA-Sensing Pathway
- (2014) Peihong Dai et al. PLoS Pathogens
- Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA
- (2013) Pu Gao et al. CELL
- Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase
- (2013) Pu Gao et al. CELL
- Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING
- (2013) Xu Zhang et al. MOLECULAR CELL
- cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
- (2013) Andrea Ablasser et al. NATURE
- Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP
- (2013) Andrea Ablasser et al. NATURE
- Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity
- (2013) John W. Schoggins et al. NATURE
- Reflections on the early development of poxvirus vectors
- (2013) Bernard Moss VACCINE
- Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity
- (2013) Philip J. Kranzusch et al. Cell Reports
- The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING
- (2013) Elie J. Diner et al. Cell Reports
- Poxviruses Deploy Genomic Accordions to Adapt Rapidly against Host Antiviral Defenses
- (2012) Nels C. Elde et al. CELL
- Skin infection generates non-migratory memory CD8+ TRM cells providing global skin immunity
- (2012) Xiaodong Jiang et al. NATURE
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Nucleases: diversity of structure, function and mechanism
- (2010) Wei Yang QUARTERLY REVIEWS OF BIOPHYSICS
- Novel mutations in Moloney Murine Leukemia Virus reverse transcriptase increase thermostability through tighter binding to template-primer
- (2008) Bahram Arezi et al. NUCLEIC ACIDS RESEARCH
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