Biased G Protein-Independent Signaling of Dopamine D1-D3 Receptor Heteromers in the Nucleus Accumbens

Behavioral and cellular dopamine D 1 and D 3 receptor-mediated synergy: Implications for L-DOPA-induced dyskinesia

(2018) Kathryn Lanza et al.   NEUROPHARMACOLOGY

Gs- versus Golf-dependent functional selectivity mediated by the dopamine D1 receptor

(2018) Hideaki Yano et al.   Nature Communications

Evidence for functional pre-coupled complexes of receptor heteromers and adenylyl cyclase

(2018) Gemma Navarro et al.   Nature Communications

Antipsychotic-Like Efficacy of Dopamine D2 Receptor-Biased Ligands is Dependent on Adenosine A2A Receptor Expression

(2017) Kristoffer Sahlholm et al.   MOLECULAR NEUROBIOLOGY

Highly Selective Dopamine D3 Receptor (D3R) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment

(2016) Vivek Kumar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis

(2015) Thomas M. Keck et al.   JOURNAL OF MEDICINAL CHEMISTRY

Allosteric interactions between agonists and antagonists within the adenosine A2Areceptor-dopamine D2receptor heterotetramer

(2015) Jordi Bonaventura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The GPCR heterotetramer: challenging classical pharmacology

(2015) Sergi Ferré   TRENDS IN PHARMACOLOGICAL SCIENCES

Stronger Dopamine D1 Receptor-Mediated Neurotransmission in Dyskinesia

(2014) Daniel Farré et al.   MOLECULAR NEUROBIOLOGY

Biased ligands at G-protein-coupled receptors: promise and progress

(2014) Jonathan D. Violin et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Transient and rapid activation of Akt/GSK-3β and mTORC1 signaling by D3 dopamine receptor stimulation in dorsal striatum and nucleus accumbens

(2013) Marie-Josèphe Salles et al.   JOURNAL OF NEUROCHEMISTRY

Prime Time for G-Protein-Coupled Receptor Heteromers as Therapeutic Targets for CNS disorders: The Dopamine D1-D3 Receptor Heteromer

(2012) Sergi Ferre et al.   CNS & Neurological Disorders-Drug Targets

Molecular Mechanism of β-Arrestin-Biased Agonism at Seven-Transmembrane Receptors

(2011) Eric Reiter et al.   Annual Review of Pharmacology and Toxicology

Upregulation of D2-class signaling in dopamine-denervated striatum is in part mediated by D3 receptors acting on CaV2.1 channels via PIP2 depletion

(2011) G. Aleph Prieto et al.   JOURNAL OF NEUROPHYSIOLOGY

Facilitation of μ-Opioid Receptor Activity by Preventing δ-Opioid Receptor-Mediated Codegradation

(2011) Shao-Qiu He et al.   NEURON

Dopamine promotes striatal neuronal apoptotic death via ERK signaling cascades

(2009) Jun Chen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Striatal Akt/GSK3 signaling pathway in the development of L-Dopa-induced dyskinesias in MPTP monkeys

(2009) Marc Morissette et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Identification of Dopamine D1–D3Receptor Heteromers

(2008) Daniel Marcellino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reciprocal Regulation of Dopamine D1 and D3 Receptor Function and Trafficking by Heterodimerization

(2008) C. Fiorentini et al.   MOLECULAR PHARMACOLOGY

Detection of heteromerization of more than two proteins by sequential BRET-FRET

(2008) Paulina Carriba et al.   NATURE METHODS