Gs- versus Golf-dependent functional selectivity mediated by the dopamine D1 receptor

Toward Understanding the Structural Basis of Partial Agonism at the Dopamine D3 Receptor

(2017) Mayako Michino et al.   JOURNAL OF MEDICINAL CHEMISTRY

RCD+: Fast loop modeling server

(2016) José Ramón López-Blanco et al.   NUCLEIC ACIDS RESEARCH

Identification of G Protein-Biased Agonists That Fail To Recruit β-Arrestin or Promote Internalization of the D1 Dopamine Receptor

(2015) Jennie L. Conroy et al.   ACS Chemical Neuroscience

Structural basis for Na+-sensitivity in dopamine D2 and D3 receptors

(2015) Mayako Michino et al.   CHEMICAL COMMUNICATIONS

Molecular Determinants of Biased Agonism at the Dopamine D2 Receptor

(2015) Dietmar Weichert et al.   JOURNAL OF MEDICINAL CHEMISTRY

GPCRdb: an information system for G protein-coupled receptors

(2015) Vignir Isberg et al.   NUCLEIC ACIDS RESEARCH

Structure–Activity Relationships of Privileged Structures Lead to the Discovery of Novel Biased Ligands at the Dopamine D2 Receptor

(2014) Monika Szabo et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Functional Selectivity Mechanism at the Serotonin-2A GPCR Involves Ligand-Dependent Conformations of Intracellular Loop 2

(2014) Jose Manuel Perez-Aguilar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

D1R/GluN1 complexes in the striatum integrate dopamine and glutamate signalling to control synaptic plasticity and cocaine-induced responses

(2014) E Cahill et al.   MOLECULAR PSYCHIATRY

Effects of the D1 Dopamine Receptor Agonist Dihydrexidine (DAR-0100A) on Working Memory in Schizotypal Personality Disorder

(2014) Daniel R Rosell et al.   NEUROPSYCHOPHARMACOLOGY

Biased ligands at G-protein-coupled receptors: promise and progress

(2014) Jonathan D. Violin et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Molecular signatures of G-protein-coupled receptors

(2013) A. J. Venkatakrishnan et al.   NATURE

Single-molecule imaging of the functional crosstalk between surface NMDA and dopamine D1 receptors

(2013) L. Ladepeche et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Features for Functional Selectivity at Serotonin Receptors

(2013) D. Wacker et al.   SCIENCE

New concepts in pharmacological efficacy at 7TM receptors: IUPHAR Review 2

(2012) Terry Kenakin   BRITISH JOURNAL OF PHARMACOLOGY

D1-NMDA receptor interactions in the rat nucleus accumbens change during adolescence

(2012) Frédéric Huppé-Gourgues et al.   SYNAPSE

Few Residues within an Extensive Binding Interface Drive Receptor Interaction and Determine the Specificity of Arrestin Proteins

(2011) Sergey A. Vishnivetskiy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CODA-RET reveals functional selectivity as a result of GPCR heteromerization

(2011) Eneko Urizar et al.   Nature Chemical Biology

Discovery of  -Arrestin-Biased Dopamine D2 Ligands for Probing Signal Transduction Pathways Essential for Antipsychotic Efficacy

(2011) J. A. Allen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β-arrestin-mediated receptor trafficking and signal transduction

(2011) Sudha K. Shenoy et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Identification of a Specific Assembly of the G Protein Golf as a Critical and Regulated Module of Dopamine and Adenosine-Activated cAMP Pathways in the Striatum

(2011) Denis Hervé   Frontiers in Neuroanatomy

Characterization of in vivo Pharmacokinetic Properties of the Dopamine D1 Receptor Agonist DAR-0100A in Nonhuman Primates Using PET with [11C] NNC112 and [11C] Raclopride

(2010) Mark Slifstein et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A Dopamine D1 Receptor-Dependent β-Arrestin Signaling Complex Potentially Regulates Morphine-Induced Psychomotor Activation but not Reward in Mice

(2010) Nikhil M Urs et al.   NEUROPSYCHOPHARMACOLOGY

Fine-tuning of GPCR activity by receptor-interacting proteins

(2009) Stefanie L. Ritter et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Differential electrophysiological properties of dopamine D1 and D2 receptor-containing striatal medium-sized spiny neurons

(2008) Carlos Cepeda et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Comparison of the enantiomers of (±)-doxanthrine, a high efficacy full dopamine D1 receptor agonist, and a reversal of enantioselectivity at D1 versus alpha2C adrenergic receptors

(2008) Julie A. Przybyla et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Identification of Dopamine D1–D3Receptor Heteromers

(2008) Daniel Marcellino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dopamine D1receptor ligands: Where are we now and where are we going

(2008) Jing Zhang et al.   MEDICINAL RESEARCH REVIEWS

Reciprocal Regulation of Dopamine D1 and D3 Receptor Function and Trafficking by Heterodimerization

(2008) C. Fiorentini et al.   MOLECULAR PHARMACOLOGY