Bone marrow stromal cells from β-thalassemia patients have impaired hematopoietic supportive capacity
出版年份 2019 全文链接
标题
Bone marrow stromal cells from β-thalassemia patients have impaired hematopoietic supportive capacity
作者
关键词
-
出版物
JOURNAL OF CLINICAL INVESTIGATION
Volume -, Issue -, Pages -
出版商
American Society for Clinical Investigation
发表日期
2019-02-25
DOI
10.1172/jci123191
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Effects of intracellular iron overload on cell death and identification of potent cell death inhibitors
- (2018) Shenglin Fang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The hematopoietic stem cell niche: What's so special about bone?
- (2018) Benjamin J. Frisch BONE
- Thalassaemia
- (2018) Ali T Taher et al. LANCET
- Bone disease in β thalassemia patients: past, present and future perspectives
- (2018) Vincenzo De Sanctis et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Gene Therapy Approaches to Hemoglobinopathies
- (2017) Giuliana Ferrari et al. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
- Complexity of bone marrow hematopoietic stem cell niche
- (2017) Noboru Asada et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Iron Overload and Chelation Therapy in Non-Transfusion Dependent Thalassemia
- (2017) Rayan Bou-Fakhredin et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Bone Niches, Hematopoietic Stem Cells, and Vessel Formation
- (2017) Roberto Tamma et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Versatile humanized niche model enables study of normal and malignant human hematopoiesis
- (2017) Ander Abarrategi et al. JOURNAL OF CLINICAL INVESTIGATION
- Differential cytokine contributions of perivascular haematopoietic stem cell niches
- (2017) Noboru Asada et al. NATURE CELL BIOLOGY
- Gene Therapy with Hematopoietic Stem Cells: The Diseased Bone Marrow's Point of View
- (2017) Marina Cavazzana et al. STEM CELLS AND DEVELOPMENT
- Total antioxidant capacity in Mediterranean β-thalassemic patients
- (2017) Ioannis Tsamesidis et al. Advances in Clinical and Experimental Medicine
- Oxidative stress promotes exit from the stem cell state and spontaneous neuronal differentiation
- (2017) Qidong Hu et al. Oncotarget
- Bioengineering of Humanized Bone Marrow Microenvironments in Mouse and Their Visualization by Live Imaging
- (2017) Diana Passaro et al. Jove-Journal of Visualized Experiments
- Isolation and characterization of primary bone marrow mesenchymal stromal cells
- (2016) Hongzhe Li et al. Annals of the New York Academy of Sciences
- Hemopoietic stem cell transplantation in thalassemia: a report from the European Society for Blood and Bone Marrow Transplantation Hemoglobinopathy Registry, 2000–2010
- (2016) D Baronciani et al. BONE MARROW TRANSPLANTATION
- Bone marrow–derived CD34 − fraction: A rich source of mesenchymal stromal cells for clinical application
- (2016) Daniela Maria Ingo et al. CYTOTHERAPY
- Macrophages and Iron Metabolism
- (2016) Miguel P. Soares et al. IMMUNITY
- Bone marrow-derived and resident liver macrophages display unique transcriptomic signatures but similar biological functions
- (2016) Lynette Beattie et al. JOURNAL OF HEPATOLOGY
- Safer conditioning for blood stem cell transplants
- (2016) Alessandro Aiuti et al. NATURE BIOTECHNOLOGY
- Dual Role of ROS as Signal and Stress Agents: Iron Tips the Balance in favor of Toxic Effects
- (2016) Elena Gammella et al. Oxidative Medicine and Cellular Longevity
- Optimal Outcomes in Young Class 3 Patients With Thalassemia Undergoing HLA-Identical Sibling Bone Marrow Transplantation
- (2016) Javid Gaziev et al. TRANSPLANTATION
- Roles of FGF signaling in stem cell self-renewal, senescence and aging
- (2016) Daniel L. Coutu et al. Aging-US
- Drug-releasing mesenchymal cells strongly suppress B16 lung metastasis in a syngeneic murine model
- (2015) Augusto Pessina et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The Role of Reactive Oxygen Species in Mesenchymal Stem Cell Adipogenic and Osteogenic Differentiation: A Review
- (2015) Fatemeh Atashi et al. STEM CELLS AND DEVELOPMENT
- Effects of Iron Overload on the Bone Marrow Microenvironment in Mice
- (2015) Yuchen Zhang et al. PLoS One
- ROS-mediated iron overload injures the hematopoiesis of bone marrow by damaging hematopoietic stem/progenitor cells in mice
- (2015) Xiao Chai et al. Scientific Reports
- Reactive Oxygen Species Regulate Hematopoietic Stem Cell Self-Renewal, Migration and Development, As Well As Their Bone Marrow Microenvironment
- (2014) Aya Ludin et al. ANTIOXIDANTS & REDOX SIGNALING
- Preclinical Evaluation of Efficacy and Safety of an Improved Lentiviral Vector for the Treatment of β-Thalassemia and Sickle Cell Disease
- (2014) Olivier Negre et al. CURRENT GENE THERAPY
- Human mesenchymal stromal cells primed with paclitaxel, apart from displaying anti-tumor activity, maintain their immune regulatory functions in vitro
- (2014) Antonella Conforti et al. CYTOTHERAPY
- Stem cells and the impact of ROS signaling
- (2014) C. L. Bigarella et al. DEVELOPMENT
- The bone marrow hematopoietic microenvironment is impaired in iron-overloaded mice
- (2014) Hiroshi Okabe et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Hematopoietic stem cell transplantation in thalassemia major and sickle cell disease: indications and management recommendations from an international expert panel
- (2014) E. Angelucci et al. HAEMATOLOGICA
- Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: A new approach for drug delivery
- (2014) Luisa Pascucci et al. JOURNAL OF CONTROLLED RELEASE
- Targeted genome editing in human repopulating haematopoietic stem cells
- (2014) Pietro Genovese et al. NATURE
- The bone marrow niche for haematopoietic stem cells
- (2014) Sean J. Morrison et al. NATURE
- Hematopoietic stem cell niche maintenance during homeostasis and regeneration
- (2014) Avital Mendelson et al. NATURE MEDICINE
- Mesenchymal Stromal Cells: Sensors and Switchers of Inflammation
- (2013) Maria Ester Bernardo et al. Cell Stem Cell
- Modulation of intracellular iron metabolism by iron chelation affects chromatin remodeling proteins and corresponding epigenetic modifications in breast cancer cells and increases their sensitivity to chemotherapeutic agents
- (2013) IGOR P. POGRIBNY et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- World Distribution, Population Genetics, and Health Burden of the Hemoglobinopathies
- (2013) T. N. Williams et al. Cold Spring Harbor Perspectives in Medicine
- The Molecular Basis of -Thalassemia
- (2013) S. L. Thein Cold Spring Harbor Perspectives in Medicine
- LNGFR+THY-1+VCAM-1hi+ Cells Reveal Functionally Distinct Subpopulations in Mesenchymal Stem Cells
- (2013) Yo Mabuchi et al. Stem Cell Reports
- Role of N-cadherin in the regulation of hematopoietic stem cells in the bone marrow niche
- (2012) Fumio Arai et al. Annals of the New York Academy of Sciences
- Roles of Reactive Oxygen Species in the Fate of Stem Cells
- (2012) Pooja Chaudhari et al. ANTIOXIDANTS & REDOX SIGNALING
- Ferroportin-mediated iron transport: Expression and regulation
- (2012) Diane M. Ward et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mammalian iron metabolism and its control by iron regulatory proteins
- (2012) Cole P. Anderson et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Allogeneic hematopoietic stem cell transplantation in thalassemia major: results of a reduced-toxicity conditioning regimen based on the use of treosulfan
- (2012) M. E. Bernardo et al. BLOOD
- Redox regulation of stem/progenitor cells and bone marrow niche
- (2012) Norifumi Urao et al. FREE RADICAL BIOLOGY AND MEDICINE
- Cord-Blood Engraftment with Ex Vivo Mesenchymal-Cell Coculture
- (2012) Marcos de Lima et al. NEW ENGLAND JOURNAL OF MEDICINE
- Non-transferrin bound iron: A key role in iron overload and iron toxicity
- (2011) Pierre Brissot et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- How I treat thalassemia
- (2011) E. A. Rachmilewitz et al. BLOOD
- CD146 expression on primary nonhematopoietic bone marrow stem cells is correlated with in situ localization
- (2011) A. Tormin et al. BLOOD
- Iron overload thalassemic cardiomyopathy: Iron status assessment and mechanisms of mechanical and electrical disturbance due to iron toxicity
- (2011) Suree Lekawanvijit et al. CANADIAN JOURNAL OF CARDIOLOGY
- Reactive oxygen species and hematopoietic stem cell senescence
- (2011) Lijian Shao et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Use of In Vivo Gene Expression of Isolated Bone Marrow Mesenchymal Stromal Cells to Study the Pathophysiology of Osteoporosis in Patients With Severe Thalassemia
- (2011) Suradej Hongeng et al. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
- Thalassaemia
- (2011) Douglas R Higgs et al. LANCET
- Reactive oxygen species mediate adipocyte differentiation in mesenchymal stem cells
- (2011) Yasunari Kanda et al. LIFE SCIENCES
- Hematopoietic Stem Cell Transplantation in Thalassemia
- (2011) E. Angelucci Hematology-American Society of Hematology Education Program
- Genetic Therapy for Beta-Thalassemia: From the Bench to the Bedside
- (2011) P. Arumugam et al. Hematology-American Society of Hematology Education Program
- A preclinical approach for gene therapy of β-thalassemia
- (2010) Laura Breda et al. Annals of the New York Academy of Sciences
- Bone loss caused by iron overload in a murine model: importance of oxidative stress
- (2010) J. Tsay et al. BLOOD
- Co-infusion of ex vivo-expanded, parental MSCs prevents life-threatening acute GVHD, but does not reduce the risk of graft failure in pediatric patients undergoing allogeneic umbilical cord blood transplantation
- (2010) M E Bernardo et al. BONE MARROW TRANSPLANTATION
- Histone Methyl Transferases and Demethylases; Can They Link Metabolism and Transcription?
- (2010) Raffaele Teperino et al. Cell Metabolism
- Correction of β-thalassemia major by gene transfer in haematopoietic progenitors of pediatric patients
- (2010) Emanuela Anna Roselli et al. EMBO Molecular Medicine
- The Essential Functions of Adipo-osteogenic Progenitors as the Hematopoietic Stem and Progenitor Cell Niche
- (2010) Yoshiki Omatsu et al. IMMUNITY
- Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
- (2010) Simón Méndez-Ferrer et al. NATURE
- Interleukin-6 maintains bone marrow-derived mesenchymal stem cell stemness by an ERK1/2-dependent mechanism
- (2009) Katie L. Pricola et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Intracellular Iron Transport and Storage: From Molecular Mechanisms to Health Implications
- (2008) Elizabeth L. Mackenzie et al. ANTIOXIDANTS & REDOX SIGNALING
- Isolation of functionally distinct mesenchymal stem cell subsets using antibodies against CD56, CD271, and mesenchymal stem cell antigen-1
- (2008) V. L. Battula et al. HAEMATOLOGICA
- Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study
- (2008) Katarina Le Blanc et al. LANCET
- In vivo selection of genetically modified erythroblastic progenitors leads to long-term correction of -thalassemia
- (2008) A. Miccio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Advances in the allogeneic transplantation for thalassemia
- (2007) Guido Lucarelli et al. BLOOD REVIEWS
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