标题
Hematopoietic stem cell niche maintenance during homeostasis and regeneration
作者
关键词
-
出版物
NATURE MEDICINE
Volume 20, Issue 8, Pages 833-846
出版商
Springer Nature
发表日期
2014-08-07
DOI
10.1038/nm.3647
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Reprogramming Committed Murine Blood Cells to Induced Hematopoietic Stem Cells with Defined Factors
- (2014) Jonah Riddell et al. CELL
- Vasculature-Associated Cells Expressing Nestin in Developing Bones Encompass Early Cells in the Osteoblast and Endothelial Lineage
- (2014) Noriaki Ono et al. DEVELOPMENTAL CELL
- Osterix Marks Distinct Waves of Primitive and Definitive Stromal Progenitors during Bone Marrow Development
- (2014) Toshihide Mizoguchi et al. DEVELOPMENTAL CELL
- Re-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type I interferons
- (2014) Eric M. Pietras et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Targeted genome editing in human repopulating haematopoietic stem cells
- (2014) Pietro Genovese et al. NATURE
- The bone marrow niche for haematopoietic stem cells
- (2014) Sean J. Morrison et al. NATURE
- Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR–Cas platform
- (2014) K. Yoshimi et al. Nature Communications
- Mesenchymal Stem Cell: Keystone of the Hematopoietic Stem Cell Niche and a Stepping-Stone for Regenerative Medicine
- (2013) Paul S. Frenette et al. Annual Review of Immunology
- Optimizing Autologous Stem Cell Mobilization Strategies to Improve Patient Outcomes: Consensus Guidelines and Recommendations
- (2013) Sergio Giralt et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Interferon- impairs proliferation of hematopoietic stem cells in mice
- (2013) A. M. de Bruin et al. BLOOD
- Coordinated and unique functions of the E-selectin ligand ESL-1 during inflammatory and hematopoietic recruitment in mice
- (2013) V. Sreeramkumar et al. BLOOD
- CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age
- (2013) C. Gekas et al. BLOOD
- TXNIP Maintains the Hematopoietic Cell Pool by Switching the Function of p53 under Oxidative Stress
- (2013) Haiyoung Jung et al. Cell Metabolism
- Mechanisms that Regulate Stem Cell Aging and Life Span
- (2013) Robert A.J. Signer et al. Cell Stem Cell
- Regional Localization within the Bone Marrow Influences the Functional Capacity of Human HSCs
- (2013) Borhane Guezguez et al. Cell Stem Cell
- Induction of a Hemogenic Program in Mouse Fibroblasts
- (2013) Carlos-Filipe Pereira et al. Cell Stem Cell
- Deciphering Hematopoietic Stem Cells in Their Niches: A Critical Appraisal of Genetic Models, Lineage Tracing, and Imaging Strategies
- (2013) Chacko Joseph et al. Cell Stem Cell
- In Vivo Mapping of Notch Pathway Activity in Normal and Stress Hematopoiesis
- (2013) Philmo Oh et al. Cell Stem Cell
- Myeloproliferative Neoplasia Remodels the Endosteal Bone Marrow Niche into a Self-Reinforcing Leukemic Niche
- (2013) Koen Schepers et al. Cell Stem Cell
- Contractile Forces Sustain and Polarize Hematopoiesis from Stem and Progenitor Cells
- (2013) Jae-Won Shin et al. Cell Stem Cell
- Cdc42 and aging of hematopoietic stem cells
- (2013) Hartmut Geiger et al. CURRENT OPINION IN HEMATOLOGY
- Molecular Signatures of Tissue-Specific Microvascular Endothelial Cell Heterogeneity in Organ Maintenance and Regeneration
- (2013) Daniel J. Nolan et al. DEVELOPMENTAL CELL
- The Satb1 Protein Directs Hematopoietic Stem Cell Differentiation toward Lymphoid Lineages
- (2013) Yusuke Satoh et al. IMMUNITY
- Lessons Learned about Human Stem Cell Responses to Ionizing Radiation Exposures: A Long Road Still Ahead of Us
- (2013) Mykyta Sokolov et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy
- (2013) Fabienne Brenet et al. JOURNAL OF EXPERIMENTAL MEDICINE
- PDGFRα and CD51 mark human Nestin+sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion
- (2013) Sandra Pinho et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing
- (2013) Maria Carolina Florian et al. NATURE
- CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance
- (2013) Adam Greenbaum et al. NATURE
- Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches
- (2013) Lei Ding et al. NATURE
- Arteriolar niches maintain haematopoietic stem cell quiescence
- (2013) Yuya Kunisaki et al. NATURE
- Quantitative imaging of haematopoietic stem and progenitor cell localization and hypoxic status in the bone marrow microenvironment
- (2013) César Nombela-Arrieta et al. NATURE CELL BIOLOGY
- Epidermal growth factor regulates hematopoietic regeneration after radiation injury
- (2013) Phuong L Doan et al. NATURE MEDICINE
- Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia
- (2013) Pedro Ramos et al. NATURE MEDICINE
- Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration
- (2013) Daniel Lucas et al. NATURE MEDICINE
- CD169+ macrophages provide a niche promoting erythropoiesis under homeostasis and stress
- (2013) Andrew Chow et al. NATURE MEDICINE
- Osterix-Cre Labeled Progenitor Cells Contribute to the Formation and Maintenance of the Bone Marrow Stroma
- (2013) Yaling Liu et al. PLoS One
- Regulation of human hematopoietic stem cell self-renewal by the microenvironment's control of retinoic acid signaling
- (2013) G. Ghiaur et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications
- (2013) T. Sato et al. SCIENCE
- Wnt5a Regulates Hematopoietic Stem Cell Proliferation and Repopulation Through the Ryk Receptor
- (2013) Benjamin J. Povinelli et al. STEM CELLS
- Loss of Aryl Hydrocarbon Receptor Promotes Gene Changes Associated with Premature Hematopoietic Stem Cell Exhaustion and Development of a Myeloproliferative Disorder in Aging Mice
- (2013) Kameshwar P. Singh et al. STEM CELLS AND DEVELOPMENT
- Review of therapeutic options and the management of patients with myelodysplastic syndromes
- (2013) Mehmet A Özcan et al. Expert Review of Hematology
- Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion
- (2013) Joan Isern et al. Cell Reports
- Endothelial Jagged-1 Is Necessary for Homeostatic and Regenerative Hematopoiesis
- (2013) Michael G. Poulos et al. Cell Reports
- It takes 2 to thrombopoies in the vascular niche
- (2012) E. Gars et al. BLOOD
- Hematopoietic stem cells lacking Ott1 display aspects associated with aging and are unable to maintain quiescence during proliferative stress
- (2012) N. Xiao et al. BLOOD
- FGF signaling facilitates postinjury recovery of mouse hematopoietic system
- (2012) M. Zhao et al. BLOOD
- Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing
- (2012) A. V. Ergen et al. BLOOD
- Hematopoietic stem cells: to be or Notch to be
- (2012) A. Bigas et al. BLOOD
- Extracellular matrix protein tenascin-C is required in the bone marrow microenvironment primed for hematopoietic regeneration
- (2012) A. Nakamura-Ishizu et al. BLOOD
- LRF-mediated Dll4 repression in erythroblasts is necessary for hematopoietic stem cell maintenance
- (2012) S.-U. Lee et al. BLOOD
- Norepinephrine reuptake inhibition promotes mobilization in mice: potential impact to rescue low stem cell yields
- (2012) D. Lucas et al. BLOOD
- VEGFR1 stimulates a CXCR4-dependent translocation of megakaryocytes to the vascular niche, enhancing platelet production in mice
- (2012) S. C. Pitchford et al. BLOOD
- N-cadherin in osteolineage cells is not required for maintenance of hematopoietic stem cells
- (2012) A. M. Greenbaum et al. BLOOD
- Osteoblastic N-cadherin is not required for microenvironmental support and regulation of hematopoietic stem and progenitor cells
- (2012) O. Bromberg et al. BLOOD
- Mesenchymal progenitors residing close to the bone surface are functionally distinct from those in the central bone marrow
- (2012) Valerie A. Siclari et al. BONE
- Stem cells of the human epidermis and their niche: composition and function in epidermal regeneration and carcinogenesis
- (2012) K. Boehnke et al. CARCINOGENESIS
- DNA-Damage-Induced Differentiation in Hematopoietic Stem Cells
- (2012) Pankaj K. Mandal et al. CELL
- A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage
- (2012) Jianwei Wang et al. CELL
- Noncanonical Wnt Signaling Maintains Hematopoietic Stem Cells in the Niche
- (2012) Ryohichi Sugimura et al. CELL
- Rapid Expansion of Human Hematopoietic Stem Cells by Automated Control of Inhibitory Feedback Signaling
- (2012) Elizabeth Csaszar et al. Cell Stem Cell
- Hematopoiesis: A Human Perspective
- (2012) Sergei Doulatov et al. Cell Stem Cell
- Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration
- (2012) Dongsu Park et al. Cell Stem Cell
- Cdc42 Activity Regulates Hematopoietic Stem Cell Aging and Rejuvenation
- (2012) Maria Carolina Florian et al. Cell Stem Cell
- Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling
- (2012) Paul D. Ray et al. CELLULAR SIGNALLING
- The hematopoietic stem cell niche-home for friend and foe?
- (2012) Daniela S. Krause et al. CYTOMETRY PART B-CLINICAL CYTOMETRY
- Identification of a clonally expanding haematopoietic compartment in bone marrow
- (2012) Lin Wang et al. EMBO JOURNAL
- Dissecting the bulge in hair regeneration
- (2012) Peggy Myung et al. JOURNAL OF CLINICAL INVESTIGATION
- Endothelial and perivascular cells maintain haematopoietic stem cells
- (2012) Lei Ding et al. NATURE
- Pharmacological targeting of the thrombomodulin–activated protein C pathway mitigates radiation toxicity
- (2012) Hartmut Geiger et al. NATURE MEDICINE
- Tie2+Bone Marrow Endothelial Cells Regulate Hematopoietic Stem Cell Regeneration Following Radiation Injury
- (2012) Phuong L. Doan et al. STEM CELLS
- Alcam Regulates Long-Term Hematopoietic Stem Cell Engraftment and Self-Renewal
- (2012) Robin Jeannet et al. STEM CELLS
- Pleiotrophin Regulates the Retention and Self-Renewal of Hematopoietic Stem Cells in the Bone Marrow Vascular Niche
- (2012) Heather A. Himburg et al. Cell Reports
- Ex vivo expansion of human hematopoietic stem and progenitor cells
- (2011) A. Dahlberg et al. BLOOD
- Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells
- (2011) T. Yahata et al. BLOOD
- Stromal pleiotrophin regulates repopulation behavior of hematopoietic stem cells
- (2011) R. Istvanffy et al. BLOOD
- Differential niche and Wnt requirements during acute myeloid leukemia progression
- (2011) S. W. Lane et al. BLOOD
- The relationship between bone, hemopoietic stem cells, and vasculature
- (2011) S. L. Ellis et al. BLOOD
- Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche
- (2011) Satoshi Yamazaki et al. CELL
- Accumulating Mitochondrial DNA Mutations Drive Premature Hematopoietic Aging Phenotypes Distinct from Physiological Stem Cell Aging
- (2011) Gudmundur L. Norddahl et al. Cell Stem Cell
- Cripto Regulates Hematopoietic Stem Cells as a Hypoxic-Niche-Related Factor through Cell Surface Receptor GRP78
- (2011) Kenichi Miharada et al. Cell Stem Cell
- Ex Vivo Expanded Hematopoietic Stem Cells Overcome the MHC Barrier in Allogeneic Transplantation
- (2011) Junke Zheng et al. Cell Stem Cell
- Robo4 Cooperates with Cxcr4 to Specify Hematopoietic Stem Cell Localization to Bone Marrow Niches
- (2011) Stephanie Smith-Berdan et al. Cell Stem Cell
- Canonical Wnt Signaling Regulates Hematopoiesis in a Dosage-Dependent Fashion
- (2011) Tiago C. Luis et al. Cell Stem Cell
- Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
- (2011) Toshio Suda et al. Cell Stem Cell
- Mastermind-like 1 (MamL1) and mastermind-like 3 (MamL3) are essential for Notch signaling in vivo
- (2011) T. Oyama et al. DEVELOPMENT
- An Irradiation-Altered Bone Marrow Microenvironment Impacts Anabolic Actions of PTH
- (2011) A. J. Koh et al. ENDOCRINOLOGY
- Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells
- (2011) Barbara Varnum-Finney et al. JOURNAL OF CLINICAL INVESTIGATION
- Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells
- (2011) Brad Dykstra et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice
- (2011) Matthew J. Christopher et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization
- (2011) Kana Miyamoto et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Bone marrow CD169+macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche
- (2011) Andrew Chow et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Notch signaling in mammalian hematopoietic stem cells
- (2011) K V Pajcini et al. LEUKEMIA
- The ageing systemic milieu negatively regulates neurogenesis and cognitive function
- (2011) Saul A. Villeda et al. NATURE
- CXCL12 secretion by bone marrow stromal cells is dependent on cell contact and mediated by connexin-43 and connexin-45 gap junctions
- (2011) Amir Schajnovitz et al. NATURE IMMUNOLOGY
- Dynamic niches in the origination and differentiation of haematopoietic stem cells
- (2011) Leo D. Wang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Radiation Rescue: Mesenchymal Stromal Cells Protect from Lethal Irradiation
- (2011) Claudia Lange et al. PLoS One
- Irradiation induces bone injury by damaging bone marrow microenvironment for stem cells
- (2011) X. Cao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanisms controlling hematopoietic stem cell functions during normal hematopoiesis and hematological malignancies
- (2011) Matthew R. Warr et al. Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- The HSC niche concept has turned 31
- (2010) Stefania Lymperi et al. Annals of the New York Academy of Sciences
- An in vivo model to study and manipulate the hematopoietic stem cell niche
- (2010) J. Song et al. BLOOD
- Endothelial protein C receptor-expressing hematopoietic stem cells reside in the perisinusoidal niche in fetal liver
- (2010) H. Iwasaki et al. BLOOD
- Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs
- (2010) I. G. Winkler et al. BLOOD
- Pharmacologic modulation of the calcium-sensing receptor enhances hematopoietic stem cell lodgment in the adult bone marrow
- (2010) B. S. Lam et al. BLOOD
- A Distinctive DNA Damage Response in Human Hematopoietic Stem Cells Reveals an Apoptosis-Independent Role for p53 in Self-Renewal
- (2010) Michael Milyavsky et al. Cell Stem Cell
- Cadherin-Based Adhesion Is a Potential Target for Niche Manipulation to Protect Hematopoietic Stem Cells in Adult Bone Marrow
- (2010) Kentaro Hosokawa et al. Cell Stem Cell
- Distinct Hematopoietic Stem Cell Subtypes Are Differentially Regulated by TGF-β1
- (2010) Grant A. Challen et al. Cell Stem Cell
- Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition
- (2010) Søren M. Johnson et al. JOURNAL OF CLINICAL INVESTIGATION
- Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection
- (2010) Megan T. Baldridge et al. NATURE
- Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
- (2010) Simón Méndez-Ferrer et al. NATURE
- Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells
- (2010) Jeff Holst et al. NATURE BIOTECHNOLOGY
- Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells
- (2010) Hideki Kobayashi et al. NATURE CELL BIOLOGY
- Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution
- (2010) Colleen Delaney et al. NATURE MEDICINE
- Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion
- (2010) I. Beerman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells
- (2010) Anthony E. Boitano et al. SCIENCE
- BIO5192, a small molecule inhibitor of VLA-4, mobilizes hematopoietic stem and progenitor cells
- (2009) P. Ramirez et al. BLOOD
- In vivo cellular imaging pinpoints the role of reactive oxygen species in the early steps of adult hematopoietic reconstitution
- (2009) D. Lewandowski et al. BLOOD
- Altered cellular dynamics and endosteal location of aged early hematopoietic progenitor cells revealed by time-lapse intravital imaging in long bones
- (2009) A. Kohler et al. BLOOD
- Wnt-Related Molecules and Signaling Pathway Equilibrium in Hematopoiesis
- (2009) Sachin Malhotra et al. Cell Stem Cell
- Hematopoietic Stem Cells Do Not Depend on N-Cadherin to Regulate Their Maintenance
- (2009) Mark J. Kiel et al. Cell Stem Cell
- Engraftment and Reconstitution of Hematopoiesis Is Dependent on VEGFR2-Mediated Regeneration of Sinusoidal Endothelial Cells
- (2009) Andrea T. Hooper et al. Cell Stem Cell
- Response of human hematopoietic stem and progenitor cells to energetic carbon ions
- (2009) Daniela Becker et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Biomechanical forces promote embryonic haematopoiesis
- (2009) Luigi Adamo et al. NATURE
- Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment
- (2009) Olaia Naveiras et al. NATURE
- IFNα activates dormant haematopoietic stem cells in vivo
- (2009) Marieke A. G. Essers et al. NATURE
- Impact of Mobilization and Remobilization Strategies on Achieving Sufficient Stem Cell Yields for Autologous Transplantation
- (2008) Iskra Pusic et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation
- (2008) T. C. Luis et al. BLOOD
- Microenvironment Determines Lineage Fate in a Human Model of MLL-AF9 Leukemia
- (2008) Junping Wei et al. CANCER CELL
- Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair
- (2008) Anne Wilson et al. CELL
- N-Cadherin Expression Level Distinguishes Reserved versus Primed States of Hematopoietic Stem Cells
- (2008) Jeffrey S. Haug et al. Cell Stem Cell
- Notch Signaling Specifies Megakaryocyte Development from Hematopoietic Stem Cells
- (2008) Thomas Mercher et al. Cell Stem Cell
- Canonical Notch Signaling Is Dispensable for the Maintenance of Adult Hematopoietic Stem Cells
- (2008) Ivan Maillard et al. Cell Stem Cell
- Wnt Signaling in the Niche Enforces Hematopoietic Stem Cell Quiescence and Is Necessary to Preserve Self-Renewal In Vivo
- (2008) Heather E. Fleming et al. Cell Stem Cell
- Retinoic acid and Cyp26b1 are critical regulators of osteogenesis in the axial skeleton
- (2008) K. M. Spoorendonk et al. DEVELOPMENT
- Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche
- (2008) Cristina Lo Celso et al. NATURE
- Haematopoietic stem cell release is regulated by circadian oscillations
- (2008) Simón Méndez-Ferrer et al. NATURE
- Leukemic Cells Create Bone Marrow Niches That Disrupt the Behavior of Normal Hematopoietic Progenitor Cells
- (2008) Angela Colmone et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started