ROS-mediated iron overload injures the hematopoiesis of bone marrow by damaging hematopoietic stem/progenitor cells in mice

Iron toxicity mediated by oxidative stress enhances tissue damage in an animal model of diabetes

(2014) Ana Flávia S. Sampaio et al.   BIOMETALS

Total body irradiation causes long-term mouse BM injury via induction of HSC premature senescence in an Ink4a- and Arf-independent manner

(2014) L. Shao et al.   BLOOD

The bone marrow hematopoietic microenvironment is impaired in iron-overloaded mice

(2014) Hiroshi Okabe et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Longitudinal analysis of heart and liver iron in thalassemia major patients according to chelation treatment

(2013) F. Danjou et al.   BLOOD CELLS MOLECULES AND DISEASES

Free iron catalyzes oxidative damage to hematopoietic cells/mesenchymal stem cellsin vitroand suppresses hematopoiesis in iron overload patients

(2013) Wenyi Lu et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Transfusion dependence development and disease evolution in patients with MDS and del(5q) and without transfusion needs at diagnosis

(2013) Silvia M. Rojas et al.   LEUKEMIA RESEARCH

Acute iron overload and oxidative stress in brain

(2013) Natacha E. Piloni et al.   TOXICOLOGY

Common Developmental Pathway for Primitive Erythrocytes and Multipotent Hematopoietic Progenitors in Early Mouse Development

(2013) Toshiyuki Yamane et al.   Stem Cell Reports

Improvement in Hematopoiesis after Iron Chelation Therapy with Deferasirox in Patients with Aplastic Anemia

(2012) Sung-Eun Lee et al.   ACTA HAEMATOLOGICA

Improvement of iron-mediated oxidative DNA damage in patients with transfusion-dependent myelodysplastic syndrome by treatment with deferasirox

(2012) Shohei Kikuchi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Resveratrol ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice

(2012) Heng Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

When should iron chelation therapy be considered in patients with myelodysplasia and other bone marrow failure syndromes with iron overload?

(2012) R. J. Bird et al.   INTERNAL MEDICINE JOURNAL

Iron overload impairs proliferation of erythroid progenitors cells (BFU-E) from patients with myelodysplastic syndromes

(2012) Julia Hartmann et al.   LEUKEMIA RESEARCH

Advances in iron chelation: an update

(2011) Hossein Heli et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

The effect of iron overload and chelation on erythroid differentiation

(2011) Kazuki Taoka et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Reactive oxygen species and hematopoietic stem cell senescence

(2011) Lijian Shao et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species

(2010) M. M. Juntilla et al.   BLOOD

Iron chelation therapy associated with improvement of hematopoiesis in transfusion-dependent patients

(2010) Esther Natalie Oliva et al.   TRANSFUSION

Objectives of iron chelation therapy in myelodysplastic syndromes: more than meets the eye?

(2009) V. Pullarkat   BLOOD

Iron injections in mice increase skeletal muscle iron content, induce oxidative stress and reduce exercise performance

(2009) Trent F. Reardon et al.   EXPERIMENTAL PHYSIOLOGY

Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells

(2009) Yong Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Extramedullary hematopoiesis is dysregulated in histamine-free histidine decarboxylase knockout (HDC−/−) mice

(2009) Zsuzsanna Horváth et al.   INFLAMMATION RESEARCH

Japanese epidemiological survey with consensus statement on Japanese guidelines for treatment of iron overload in bone marrow failure syndromes

(2008) Takahiro Suzuki et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY