PRMT5 enhances tumorigenicity and glycolysis in pancreatic cancer via the FBW7/cMyc axis
出版年份 2019 全文链接
标题
PRMT5 enhances tumorigenicity and glycolysis in pancreatic cancer via the FBW7/cMyc axis
作者
关键词
PRMT5, Aerobic glycolysis, cMyc, FBW7, Pancreatic cancer
出版物
Cell Communication and Signaling
Volume 17, Issue 1, Pages -
出版商
Springer Nature
发表日期
2019-03-29
DOI
10.1186/s12964-019-0344-4
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Protein arginine methyltransferase 5 mediates enolase-1 cell surface trafficking in human lung adenocarcinoma cells
- (2018) Dariusz Zakrzewicz et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Cancer statistics, 2018
- (2018) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Protein arginine methyltransferase 5 promotes lung cancer metastasis via the epigenetic regulation of miR-99 family/FGFR3 signaling
- (2018) Pengyu Jing et al. CANCER LETTERS
- Physiological functions of FBW7 in cancer and metabolism
- (2018) Kouhei Shimizu et al. CELLULAR SIGNALLING
- The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer
- (2018) Omar M. Khan et al. JOURNAL OF CLINICAL INVESTIGATION
- PTEN: Tumor Suppressor and Metabolic Regulator
- (2018) Chien-Yu Chen et al. Frontiers in Endocrinology
- Targeting protein arginine methyltransferase 5 in disease
- (2017) André Richters Future Medicinal Chemistry
- Histone Lysine Methylation and Neurodevelopmental Disorders
- (2017) Jeong-Hoon Kim et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Arginine Methylation: The Coming of Age
- (2017) Roméo S. Blanc et al. MOLECULAR CELL
- Interplay between epigenetics and metabolism in oncogenesis: mechanisms and therapeutic approaches
- (2017) C C Wong et al. ONCOGENE
- KRAS, TP53, CDKN2A, SMAD4, BRCA1, and BRCA2 Mutations in Pancreatic Cancer
- (2017) Jonas Cicenas et al. Cancers
- Arginine Methylation of SREBP1a via PRMT5 Promotes De Novo Lipogenesis and Tumor Growth
- (2016) L. Liu et al. CANCER RESEARCH
- FBW7 (F-box and WD Repeat Domain-Containing 7) Negatively Regulates Glucose Metabolism by Targeting the c-Myc/TXNIP (Thioredoxin-Binding Protein) Axis in Pancreatic Cancer
- (2016) S. Ji et al. CLINICAL CANCER RESEARCH
- Genetics and biology of pancreatic ductal adenocarcinoma
- (2016) Haoqiang Ying et al. GENES & DEVELOPMENT
- Role of protein arginine methyltransferase 5 in inflammation and migration of fibroblast-like synoviocytes in rheumatoid arthritis
- (2016) Dongying Chen et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- PRMT5–PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells
- (2016) Y K Banasavadi-Siddegowda et al. ONCOGENE
- Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor to promote prostate cancer cell growth
- (2016) X Deng et al. ONCOGENE
- Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5
- (2016) Konstantinos J. Mavrakis et al. SCIENCE
- MTAPdeletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells
- (2016) Gregory V. Kryukov et al. SCIENCE
- Regulating Fbw7 on the road to cancer
- (2016) Wenshan Xu et al. SEMINARS IN CANCER BIOLOGY
- Histone Modifications and Cancer
- (2016) James E. Audia et al. Cold Spring Harbor Perspectives in Biology
- Protein arginine methylation/demethylation and cancer
- (2016) Coralie Poulard et al. Oncotarget
- ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor
- (2016) Zineb Mounir et al. eLife
- ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer
- (2015) Shunrong Ji et al. CELL RESEARCH
- MYC, Metabolism, and Cancer
- (2015) Z. E. Stine et al. Cancer Discovery
- Myc and Omomyc functionally associate with the Protein Arginine Methyltransferase 5 (PRMT5) in glioblastoma cells
- (2015) Maria Patrizia Mongiardi et al. Scientific Reports
- Tumor Suppression by the Fbw7 Ubiquitin Ligase: Mechanisms and Opportunities
- (2014) Ryan J. Davis et al. CANCER CELL
- LSD1 sustains pancreatic cancer growth via maintaining HIF1α-dependent glycolytic process
- (2014) Yi Qin et al. CANCER LETTERS
- Epigenetic targets and drug discovery
- (2014) Yanli Liu et al. PHARMACOLOGY & THERAPEUTICS
- Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer
- (2013) Chenfang Dong et al. CANCER CELL
- Protein Arginine Methyltransferase 5 (PRMT5) Inhibition Induces Lymphoma Cell Death through Reactivation of the Retinoblastoma Tumor Suppressor Pathway and Polycomb Repressor Complex 2 (PRC2) Silencing
- (2013) Jihyun Chung et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prox1 Directly Interacts with LSD1 and Recruits the LSD1/NuRD Complex to Epigenetically Co-Repress CYP7A1 Transcription
- (2013) Huafang Ouyang et al. PLoS One
- PRMT5 dimethylates R30 of the p65 subunit to activate NF- B
- (2013) H. Wei et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fbw7 Repression by Hes5 Creates a Feedback Loop That Modulates Notch-Mediated Intestinal and Neural Stem Cell Fate Decisions
- (2013) Rocio Sancho et al. PLOS BIOLOGY
- Protein arginine methyltransferase 5 is an essential component of the hypoxia-inducible factor 1 signaling pathway
- (2012) Ji-Hong Lim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Conceptual Framework for Cutting the Pancreatic Cancer Fuel Supply
- (2012) A. Le et al. CLINICAL CANCER RESEARCH
- Histone methylation: a dynamic mark in health, disease and inheritance
- (2012) Eric L. Greer et al. NATURE REVIEWS GENETICS
- Sirtuins as regulators of metabolism and healthspan
- (2012) Riekelt H. Houtkooper et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cancer Cell Metabolism: One Hallmark, Many Faces
- (2012) Jason R. Cantor et al. Cancer Discovery
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Pancreatic cancer: Overview of descriptive epidemiology
- (2011) Cristina Bosetti et al. MOLECULAR CARCINOGENESIS
- Bromodomain protein 7 interacts with PRMT5 and PRC2, and is involved in transcriptional repression of their target genes
- (2011) Sookil Tae et al. NUCLEIC ACIDS RESEARCH
- Versatility of PRMT5-induced methylation in growth control and development
- (2011) Vrajesh Karkhanis et al. TRENDS IN BIOCHEMICAL SCIENCES
- PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing
- (2009) Quan Zhao et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Brick by brick: metabolism and tumor cell growth
- (2008) Ralph J DeBerardinis et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Protein Arginine Methyltransferase 5 Suppresses the Transcription of the RB Family of Tumor Suppressors in Leukemia and Lymphoma Cells
- (2008) L. Wang et al. MOLECULAR AND CELLULAR BIOLOGY
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