Dual-Stimuli-Responsive Gut Microbiota-Targeting Berberine-CS/PT-NPs Improved Metabolic Status in Obese Hamsters

Pectin oligosaccharides from sugar beet pulp: molecular characterization and potential prebiotic activity

(2018) Barbara Prandi et al.   Food & Function

Pectin-zinc-chitosan-polyethylene glycol colloidal nano-suspension as a food grade carrier for colon targeted delivery of resveratrol

(2017) Hashem Andishmand et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Comprehensive evaluation of SCFA production in the intestinal bacteria regulated by berberine using gas-chromatography combined with polymerase chain reaction

(2017) Lu-Lu Wang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

The gut microbiome in atherosclerotic cardiovascular disease

(2017) Zhuye Jie et al.   Nature Communications

Akkermansia MuciniphilaProtects Against Atherosclerosis by Preventing Metabolic Endotoxemia-Induced Inflammation inApoe−/−MiceCLINICAL PERSPECTIVE

(2016) Jin Li et al.   CIRCULATION

Obesity-Dependent Increases in Oocyte mRNAs Are Associated With Increases in Proinflammatory Signaling and Gut Microbial Abundance of Lachnospiraceae in Female Mice

(2016) Fang Xie et al.   ENDOCRINOLOGY

Research progress on berberine with a special focus on its oral bioavailability

(2016) Chang-Shun Liu et al.   FITOTERAPIA

Colonic inflammation accompanies an increase of β-catenin signaling and Lachnospiraceae / Streptococcaceae bacteria in the hind gut of high-fat diet-fed mice

(2016) Huawei Zeng et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Acetate mediates a microbiome–brain–β-cell axis to promote metabolic syndrome

(2016) Rachel J. Perry et al.   NATURE

Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways

(2016) Jian Tan et al.   Cell Reports

Effects of berberine on pharmacokinetics of midazolam and rhodamine 123 in rats in vivo

(2016) Hua-Wen Xin et al.   SpringerPlus

Influence of high-fat diet on gut microbiota

(2015) E. Angela Murphy et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Akkermansia muciniphilaand improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology

(2015) Maria Carlota Dao et al.   GUT

Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension

(2015) Jiarong Lan et al.   JOURNAL OF ETHNOPHARMACOLOGY

A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine

(2015) Shenghua Gu et al.   Molecular BioSystems

Dietary Gut Microbial Metabolites, Short-chain Fatty Acids, and Host Metabolic Regulation

(2015) Mayu Kasubuchi et al.   Nutrients

Modulation of gut microbiota by berberine and metformin during the treatment of high-fat diet-induced obesity in rats

(2015) Xu Zhang et al.   Scientific Reports

Berberine moderates glucose metabolism through the GnRH-GLP-1 and MAPK pathways in the intestine

(2014) Qian Zhang et al.   BMC Complementary and Alternative Medicine

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Facts, fallacies and future of dissolution testing of polysaccharide based colon-specific drug delivery

(2014) Niranjan Goud Kotla et al.   JOURNAL OF CONTROLLED RELEASE

Intestinal Microbiota, Microbial Translocation, and Systemic Inflammation in Chronic HIV Infection

(2014) Duy M. Dinh et al.   JOURNAL OF INFECTIOUS DISEASES

Characterization of Self-Assembled Polyelectrolyte Complex Nanoparticles Formed from Chitosan and Pectin

(2014) Nathan P. Birch et al.   LANGMUIR

Intestinal Colonization by a Lachnospiraceae Bacterium Contributes to the Development of Diabetes in Obese Mice

(2014) Keishi Kameyama et al.   MICROBES AND ENVIRONMENTS

Alterations of the human gut microbiome in liver cirrhosis

(2014) Nan Qin et al.   NATURE

Role of the Toll Like Receptor (TLR) Radical Cycle in Chronic Inflammation: Possible Treatments Targeting the TLR4 Pathway

(2013) Kurt Lucas et al.   MOLECULAR NEUROBIOLOGY

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A review of the potential mechanisms for the lowering of colorectal oncogenesis by butyrate

(2012) Kim Y. C. Fung et al.   BRITISH JOURNAL OF NUTRITION

The Impact of the Gut Microbiota on Human Health: An Integrative View

(2012) Jose C. Clemente et al.   CELL

Gut Hormones and Appetite Control: A Focus on PYY and GLP-1 as Therapeutic Targets in Obesity

(2012) Akila De Silva et al.   Gut and Liver

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Functional interactions between the gut microbiota and host metabolism

(2012) Valentina Tremaroli et al.   NATURE

Structural Changes of Gut Microbiota during Berberine-Mediated Prevention of Obesity and Insulin Resistance in High-Fat Diet-Fed Rats

(2012) Xu Zhang et al.   PLoS One

Bioavailability Study of Berberine and the Enhancing Effects of TPGS on Intestinal Absorption in Rats

(2011) Wei Chen et al.   AAPS PHARMSCITECH

Berberine Ameliorates Intestinal Epithelial Tight-Junction Damage and Down-regulates Myosin Light Chain Kinase Pathways in a Mouse Model of Endotoxinemia

(2011) Lili Gu et al.   JOURNAL OF INFECTIOUS DISEASES

Bifidobacteria can protect from enteropathogenic infection through production of acetate

(2011) Shinji Fukuda et al.   NATURE

Propionate as a health-promoting microbial metabolite in the human gut

(2011) Elham Hosseini et al.   NUTRITION REVIEWS

Leaky gut and diabetes mellitus: what is the link?

(2011) S. de Kort et al.   Obesity Reviews

Effects and Action Mechanisms of Berberine and Rhizoma coptidis on Gut Microbes and Obesity in High-Fat Diet-Fed C57BL/6J Mice

(2011) Weidong Xie et al.   PLoS One

Extensive Intestinal First-Pass Elimination and Predominant Hepatic Distribution of Berberine Explain Its Low Plasma Levels in Rats

(2010) Y.-T. Liu et al.   DRUG METABOLISM AND DISPOSITION

Chitosan Based Polyelectrolyte Complexes as Potential Carrier Materials in Drug Delivery Systems

(2010) Josias H. Hamman   Marine Drugs

Multiple facets of intestinal permeability and epithelial handling of dietary antigens

(2010) S Ménard et al.   Mucosal Immunology

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

(2010) C. De Filippo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

(2010) M. Vijay-Kumar et al.   SCIENCE

Diet-Induced Metabolic Improvements in a Hamster Model of Hypercholesterolemia Are Strongly Linked to Alterations of the Gut Microbiota

(2009) I. Martinez et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Hydrogel blends of chitin/chitosan, fucoidan and alginate as healing-impaired wound dressings

(2009) Kaoru Murakami et al.   BIOMATERIALS

Interactions between gut microbiota, host genetics and diet relevant to development of metabolic syndromes in mice

(2009) Chenhong Zhang et al.   ISME Journal

Application of liquid chromatography–mass spectrometry to measure short chain fatty acids in blood

(2009) Hans M.H. van Eijk et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Berberine and Coptidis Rhizoma as novel antineoplastic agents: A review of traditional use and biomedical investigations

(2009) Jun Tang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effect of berberine on the pharmacokinetics of substrates of CYP3A and P-gp

(2009) W. Qiu et al.   PHYTOTHERAPY RESEARCH

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

(2008) Peter J. Turnbaugh et al.   Cell Host & Microbe

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

(2008) P. D. Cani et al.   DIABETES

Chitosan/pectin polyelectrolyte complexes: Selection of suitable preparative conditions for colon-specific delivery of vancomycin

(2008) F. Bigucci et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Microbes in Gastrointestinal Health and Disease

(2008) Andrew S. Neish   GASTROENTEROLOGY

Incretins: pathophysiological and therapeutic implications of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1

(2008) L R Ranganath   JOURNAL OF CLINICAL PATHOLOGY

A core gut microbiome in obese and lean twins

(2008) Peter J. Turnbaugh et al.   NATURE

Gut microbiota: a potential new territory for drug targeting

(2008) Wei Jia et al.   NATURE REVIEWS DRUG DISCOVERY