Age-related change in γH2AX of Drosophila muscle: its significance as a marker for muscle damage and longevity

Recent developments in the use of γ -H2AX as a quantitative DNA double-strand break biomarker

(2016) Christophe E. Redon et al.   Aging-US

Myostatin Induces DNA Damage in Skeletal Muscle of Streptozotocin-induced Type 1 Diabetic Mice

(2014) Sandhya Sriram et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tau promotes neurodegeneration through global chromatin relaxation

(2014) Bess Frost et al.   NATURE NEUROSCIENCE

Functional Modification ofDrosophilaIntestinal Stem Cells by Ionizing Radiation

(2014) Jung-Hoon Pyo et al.   RADIATION RESEARCH

Intertissue Control of the Nucleolus via a Myokine-Dependent Longevity Pathway

(2014) Fabio Demontis et al.   Cell Reports

The influence of skeletal muscle on systemic aging and lifespan

(2013) Fabio Demontis et al.   AGING CELL

Muscle Mitohormesis Promotes Longevity via Systemic Repression of Insulin Signaling

(2013) Edward Owusu-Ansah et al.   CELL

Cell death and diseases related to oxidative stress:4-hydroxynonenal (HNE) in the balance

(2013) S Dalleau et al.   CELL DEATH AND DIFFERENTIATION

Mechanism of metformin: Inhibition of DNA damage and proliferative activity in Drosophila midgut stem cell

(2013) Hyun-Jin Na et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Rac1 modulates acute and subacute genotoxin-induced hepatic stress responses, fibrosis and liver aging

(2013) A Bopp et al.   Cell Death & Disease

Activin Signaling Targeted by Insulin/dFOXO Regulates Aging and Muscle Proteostasis in Drosophila

(2013) Hua Bai et al.   PLoS Genetics

The role of DNA damage and repair in aging through the prism of Koch-like criteria

(2012) Alexey A. Moskalev et al.   AGEING RESEARCH REVIEWS

Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response

(2012) Diana Jurk et al.   AGING CELL

DNA damage response by single-strand breaks in terminally differentiated muscle cells and the control of muscle integrity

(2012) P Fortini et al.   CELL DEATH AND DIFFERENTIATION

DNA damage, chromatin, and transcription: the trinity of aging

(2012) Rebecca C Burgess et al.   CURRENT OPINION IN CELL BIOLOGY

Age- and oxidative stress-induced DNA damage in Drosophila intestinal stem cells as marked by Gamma-H2AX

(2012) Joung-Sun Park et al.   EXPERIMENTAL GERONTOLOGY

Chromatin and the genome integrity network

(2012) Manolis Papamichos-Chronakis et al.   NATURE REVIEWS GENETICS

The great unravelling: chromatin as a modulator of the aging process

(2012) Roderick J. O'Sullivan et al.   TRENDS IN BIOCHEMICAL SCIENCES

Heterochromatin Formation Promotes Longevity and Represses Ribosomal RNA Synthesis

(2012) Kimberly Larson et al.   PLoS Genetics

A review and appraisal of the DNA damage theory of ageing

(2011) Alex A. Freitas et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People

(2010) A. J. Cruz-Jentoft et al.   AGE AND AGEING

FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging

(2010) Fabio Demontis et al.   CELL

Muscle Development and Regeneration in Normal and Pathological Conditions: Learning from Drosophila

(2010) Malgorzata Daczewska et al.   CURRENT PHARMACEUTICAL DESIGN

γH2AX as a molecular marker of aging and disease

(2010) Li-Jeen Mah et al.   Epigenetics

Unphosphorylated STAT and heterochromatin protect genome stability

(2010) Shian-Jang Yan et al.   FASEB JOURNAL

Caspase-3 Cleaves Specific 19 S Proteasome Subunits in Skeletal Muscle Stimulating Proteasome Activity

(2010) Xiaonan H. Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion

(2010) F. Rodier et al.   JOURNAL OF CELL SCIENCE

Age- and tissue-specific changes in mitochondrial and nuclear DNA base excision repair activity in mice: Susceptibility of skeletal muscles to oxidative injury

(2010) Bartosz Szczesny et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Age- and Temperature-Dependent Somatic Mutation Accumulation in Drosophila melanogaster

(2010) Ana Maria Garcia et al.   PLoS Genetics

DNA damage response and cellular senescence in tissues of aging mice

(2009) Chunfang Wang et al.   AGING CELL

Invertebrate models of age-related muscle degeneration

(2009) Hrvoje Augustin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Reactive oxygen species are signalling molecules for skeletal muscle adaptation

(2009) Scott K. Powers et al.   EXPERIMENTAL PHYSIOLOGY

Mechanisms of dealing with DNA damage in terminally differentiated cells

(2009) P. Fortini et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Exercise-Training in Young Drosophila melanogaster Reduces Age-Related Decline in Mobility and Cardiac Performance

(2009) Nicole Piazza et al.   PLoS One

Heterochromatic Genome Stability Requires Regulators of Histone H3 K9 Methylation

(2009) Jamy C. Peng et al.   PLoS Genetics

Stem Cell Review Series: Aging of the skeletal muscle stem cell niche

(2008) Suchitra D. Gopinath et al.   AGING CELL

Chromatin structure influences the sensitivity of DNA to γ-radiation

(2008) Martin Falk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

DNA double-strand breaks: A potential causative factor for mammalian aging?

(2008) Han Li et al.   MECHANISMS OF AGEING AND DEVELOPMENT