Toll-Like Receptor and miRNA-let-7e Expression Alter the Inflammatory Response in Leishmania amazonensis-Infected Macrophages

MicroRNA‑let‑7e regulates the progression and development of allergic rhinitis by targeting suppressor of cytokine signaling 4 and activating Janus kinase 1/signal transducer and activator of transcription 3 pathway

(2018) Lihua Li et al.   Experimental and Therapeutic Medicine

Arginine and Polyamines Fate in Leishmania Infection

(2018) Sandra M. Muxel et al.   Frontiers in Microbiology

miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN)

(2017) Parisa Kalantari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DIANA-TarBase v8: a decade-long collection of experimentally supported miRNA–gene interactions

(2017) Dimitra Karagkouni et al.   NUCLEIC ACIDS RESEARCH

Arginase expression modulates nitric oxide production in Leishmania (Leishmania) amazonensis

(2017) Stephanie Maia Acuña et al.   PLoS One

RNA-seq transcriptional profiling of Leishmania amazonensis reveals an arginase-dependent gene expression regulation

(2017) Juliana Ide Aoki et al.   PLoS Neglected Tropical Diseases

L-arginine availability and arginase activity: Characterization of amino acid permease 3 in Leishmania amazonensis

(2017) Juliana Ide Aoki et al.   PLoS Neglected Tropical Diseases

Leishmania (Leishmania) amazonensis induces macrophage miR-294 and miR-721 expression and modulates infection by targeting NOS2 and L-arginine metabolism

(2017) Sandra Marcia Muxel et al.   Scientific Reports

MicroRNA expression profiling of Leishmania donovani-infected host cells uncovers the regulatory role of MIR30A-3p in host autophagy

(2016) Alok Kumar Singh et al.   Autophagy

Infection of J774A.1 with differentMycobacteriumspecies induces differential immune and miRNA-related responses

(2016) Mendoza-Coronel Elizabeth et al.   MICROBIOLOGY AND IMMUNOLOGY

Dual Transcriptome Profiling of Leishmania -Infected Human Macrophages Reveals Distinct Reprogramming Signatures

(2016) Maria Cecilia Fernandes et al.   mBio

17β-Estradiol enhances the activation of IFN-α signaling in B cells by down-regulating the expression of let-7e-5p, miR-98-5p and miR-145a-5p that target IKKε

(2015) Guanjun Dong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Simultaneous transcriptional profiling of Leishmania major and its murine macrophage host cell reveals insights into host-pathogen interactions

(2015) Laura A. L. Dillon et al.   BMC GENOMICS

Permissive and protective roles for neutrophils in leishmaniasis

(2015) E. D. Carlsen et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Capillary electrophoresis reveals polyamine metabolism modulation inLeishmania (Leishmania) amazonensiswild-type and arginase-knockout mutants under arginine starvation

(2015) Emerson A. Castilho-Martins et al.   ELECTROPHORESIS

Melatonin attenuatesLeishmania (L.) amazonensisinfection by modulating arginine metabolism

(2015) Maria Fernanda Laranjeira-Silva et al.   JOURNAL OF PINEAL RESEARCH

Sequential ubiquitination and deubiquitination enzymes synchronize the dual sensor and effector functions of TRIM21

(2015) Adam J. Fletcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MiRNA and TF co-regulatory network analysis for the pathology and recurrence of myocardial infarction

(2015) Ying Lin et al.   Scientific Reports

Polymorphisms in the TOLLIP Gene Influence Susceptibility to Cutaneous Leishmaniasis Caused by Leishmania guyanensis in the Amazonas State of Brazil

(2015) Felipe Jules de Araujo et al.   PLoS Neglected Tropical Diseases

NF-κB-direct activation of microRNAs with repressive effects on monocyte-specific genes is critical for osteoclast differentiation

(2015) Lorenzo de la Rica et al.   GENOME BIOLOGY

Negatively regulating TLR4/NF-κB signaling via PPARα in endotoxin-induced uveitis

(2014) Wei Shen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

TAK1 regulates hepatic cell survival and carcinogenesis

(2014) Yoon Seok Roh et al.   JOURNAL OF GASTROENTEROLOGY

Characterization of microRNA expression profiles inLeishmania-infected human phagocytes

(2014) N. S. Geraci et al.   PARASITE IMMUNOLOGY

Inhibition of caspase-8 activity promotes protective Th1- and Th2-mediated immunity to Leishmania major infection

(2013) Wânia F. Pereira-Manfro et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Inflammasome-derived IL-1β production induces nitric oxide–mediated resistance to Leishmania

(2013) Djalma S Lima-Junior et al.   NATURE MEDICINE

MicroRNA Expression Profile in Human Macrophages in Response to Leishmania major Infection

(2013) Julien Lemaire et al.   PLoS Neglected Tropical Diseases

Differential Regulation of the Let-7 Family of MicroRNAs in CD4+ T Cells Alters IL-10 Expression

(2012) S. Swaminathan et al.   JOURNAL OF IMMUNOLOGY

Leishmania amazonensis Arginase Compartmentalization in the Glycosome Is Important for Parasite Infectivity

(2012) Maria Fernanda Laranjeira da Silva et al.   PLoS One

Leishmaniasis Worldwide and Global Estimates of Its Incidence

(2012) Jorge Alvar et al.   PLoS One

The early interaction of Leishmania with macrophages and dendritic cells and its influence on the host immune response

(2012) Dong Liu et al.   Frontiers in Cellular and Infection Microbiology

Let-7 microRNA–mediated regulation of IL-13 and allergic airway inflammation

(2011) Manish Kumar et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Identification of TLR inducing Th1-responsive Leishmania donovani amastigote-specific antigens

(2011) Ankita Srivastava et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Axenic Leishmania amazonensis Promastigotes Sense both the External and Internal Arginine Pool Distinctly Regulating the Two Transporter-Coding Genes

(2011) Emerson A. Castilho-Martins et al.   PLoS One

The E2 Ubiquitin-conjugating Enzymes Direct Polyubiquitination to Preferred Lysines

(2010) Yael David et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Kinase Akt1 Controls Macrophage Response to Lipopolysaccharide by Regulating MicroRNAs

(2009) Ariadne Androulidaki et al.   IMMUNITY

Distinct Roles for MyD88 and Toll-Like Receptor 2 during Leishmania braziliensis Infection in Mice

(2009) D. A. Vargas-Inchaustegui et al.   INFECTION AND IMMUNITY

Leishmania major parasites induced macrophage tolerance: Implication of MAPK and NF-κB pathways

(2009) Rym Ben-Othman et al.   MOLECULAR IMMUNOLOGY

Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins

(2009) Bingbing Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The involvement of TLR2 in cytokine and reactive oxygen species (ROS) production by PBMCs in response to Leishmania major phosphoglycans (PGs)

(2009) G. KAVOOSI et al.   PARASITOLOGY

Mechanisms and consequences of persistence of intracellular pathogens: leishmaniasis as an example

(2008) Christian Bogdan   CELLULAR MICROBIOLOGY

Atypical ubiquitin chains: new molecular signals. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Fumiyo Ikeda et al.   EMBO REPORTS

Leishmania mexicana: Participation of NF-κB in the differential production of IL-12 in dendritic cells and monocytes induced by lipophosphoglycan (LPG)

(2008) Jesús Argueta-Donohué et al.   EXPERIMENTAL PARASITOLOGY

The innate immune response against Leishmania parasites

(2008) Jan Liese et al.   IMMUNOBIOLOGY

Leishmania pifanoi Proteoglycolipid Complex P8 Induces Macrophage Cytokine Production through Toll-Like Receptor 4

(2008) S. M. Whitaker et al.   INFECTION AND IMMUNITY

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

(2008) Jonathan C Kagan et al.   NATURE IMMUNOLOGY