Toll-like receptor 2 is increased in neurons in Parkinson’s disease brain and may contribute to alpha-synuclein pathology
出版年份 2016 全文链接
标题
Toll-like receptor 2 is increased in neurons in Parkinson’s disease brain and may contribute to alpha-synuclein pathology
作者
关键词
Parkinson’s disease, Toll-like receptor, α-Synuclein, Autophagy, Inflammation
出版物
ACTA NEUROPATHOLOGICA
Volume 133, Issue 2, Pages 303-319
出版商
Springer Nature
发表日期
2016-11-25
DOI
10.1007/s00401-016-1648-8
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Amyloid fibrils are the molecular trigger of inflammation in Parkinson's disease
- (2015) A. Gustot et al. BIOCHEMICAL JOURNAL
- Inflammation is genetically implicated in Parkinson’s disease
- (2015) N. Dzamko et al. NEUROSCIENCE
- Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders
- (2015) Stefano G. Daniele et al. Science Signaling
- Sensitive western blotting for detection of endogenous Ser129-phosphorylated α-synuclein in intracellular and extracellular spaces
- (2015) Asuka Sasaki et al. Scientific Reports
- Antagonizing Neuronal Toll-like Receptor 2 Prevents Synucleinopathy by Activating Autophagy
- (2015) Changyoun Kim et al. Cell Reports
- Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders
- (2015) Stefano G. Daniele et al. Science Signaling
- Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson’s disease
- (2014) Karen E. Murphy et al. BRAIN
- p62 Deficiency Enhances α-Synuclein Pathology in Mice
- (2014) Kunikazu Tanji et al. BRAIN PATHOLOGY
- The Role of the Selective Adaptor p62 and Ubiquitin-Like Proteins in Autophagy
- (2014) Mónika Lippai et al. Biomed Research International
- Microglial phenotypes and toll-like receptor 2 in the substantia nigra and hippocampus of incidental Lewy body disease cases and Parkinson’s disease patients
- (2014) Karlijn J Doorn et al. Acta Neuropathologica Communications
- The role of inflammation in sporadic and familial Parkinson’s disease
- (2013) Michela Deleidi et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Toll-Like Receptor 2 Regulates Intestinal Inflammation by Controlling Integrity of the Enteric Nervous System
- (2013) Paola Brun et al. GASTROENTEROLOGY
- TLR2 & Co: a critical analysis of the complex interactions between TLR2 and coreceptors
- (2013) Jeroen van Bergenhenegouwen et al. JOURNAL OF LEUKOCYTE BIOLOGY
- p62/SQSTM1-Dependent Autophagy of Lewy Body-Like α-Synuclein Inclusions
- (2013) Yoshihisa Watanabe et al. PLoS One
- Preconditioning of Microglia by α-Synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation
- (2013) Cintia Roodveldt et al. PLoS One
- Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia
- (2013) Changyoun Kim et al. Nature Communications
- Hypothalamic neuronal toll-like receptor 2 protects against age-induced obesity
- (2013) Ravid Shechter et al. Scientific Reports
- PAMPs and DAMPs: signal 0s that spur autophagy and immunity
- (2012) Daolin Tang et al. IMMUNOLOGICAL REVIEWS
- Microglial Activation and Antioxidant Responses Induced by the Parkinson’s Disease Protein α-Synuclein
- (2012) Dawn Béraud et al. Journal of Neuroimmune Pharmacology
- Alpha-synuclein and Protein Degradation Systems: a Reciprocal Relationship
- (2012) Maria Xilouri et al. MOLECULAR NEUROBIOLOGY
- Therapeutic Effects of Rapamycin on MPTP-Induced Parkinsonism in Mice
- (2012) Kangyong Liu et al. NEUROCHEMICAL RESEARCH
- Contributions of central and systemic inflammation to the pathophysiology of Parkinson's disease
- (2012) Louise M. Collins et al. NEUROPHARMACOLOGY
- Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity
- (2011) Taro Kawai et al. IMMUNITY
- Alpha-synuclein release by neurons activates the inflammatory response in a microglial cell line
- (2011) Lydia Alvarez-Erviti et al. NEUROSCIENCE RESEARCH
- -Synuclein Activates Microglia by Inducing the Expressions of Matrix Metalloproteinases and the Subsequent Activation of Protease-Activated Receptor-1
- (2010) E.-J. Lee et al. JOURNAL OF IMMUNOLOGY
- Rapamycin Protects against Neuron Death in In Vitro andIn Vivo Models of Parkinson's Disease
- (2010) C. Malagelada et al. JOURNAL OF NEUROSCIENCE
- DAMPening Inflammation by Modulating TLR Signalling
- (2010) A. M. Piccinini et al. MEDIATORS OF INFLAMMATION
- Rapamycin protects against rotenone-induced apoptosis through autophagy induction
- (2009) T. Pan et al. NEUROSCIENCE
- The progression of pathology in longitudinally followed patients with Parkinson’s disease
- (2008) Glenda Halliday et al. ACTA NEUROPATHOLOGICA
- Synuclein activates microglia in a model of Parkinson's disease
- (2007) Xiaomin Su et al. NEUROBIOLOGY OF AGING
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