SHOC2–MRAS–PP1 complex positively regulates RAF activity and contributes to Noonan syndrome pathogenesis
出版年份 2018 全文链接
标题
SHOC2–MRAS–PP1 complex positively regulates RAF activity and contributes to Noonan syndrome pathogenesis
作者
关键词
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出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 115, Issue 45, Pages E10576-E10585
出版商
Proceedings of the National Academy of Sciences
发表日期
2018-10-23
DOI
10.1073/pnas.1720352115
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Decoding the selectivity of eIF2α holophosphatases and PPP1R15A inhibitors
- (2017) Marta Carrara et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Decoding the selectivity of eIF2α holophosphatases and PPP1R15A inhibitors
- (2017) Marta Carrara et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- De novo missense variants in PPP1CB are associated with intellectual disability and congenital heart disease
- (2016) Lijiang Ma et al. HUMAN GENETICS
- SHOC2 subcellular shuttling requires the KEKE motif-rich region andN-terminal leucine-rich repeat domain and impacts on ERK signalling
- (2016) Marialetizia Motta et al. HUMAN MOLECULAR GENETICS
- Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases
- (2016) Ying-Nan P. Chen et al. NATURE
- Metals in the active site of native protein phosphatase-1
- (2015) Ewald Heroes et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Combined Pan-RAF and MEK Inhibition Overcomes Multiple Resistance Mechanisms to Selective RAF Inhibitors
- (2015) S. R. Whittaker et al. MOLECULAR CANCER THERAPEUTICS
- Regulation of RAF protein kinases in ERK signalling
- (2015) Hugo Lavoie et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A NovelSHOC2Variant in Rasopathy
- (2014) Vickie Hannig et al. HUMAN MUTATION
- Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction
- (2014) Aidan G Gilmartin et al. Nature Chemical Biology
- Targeting the disordered C terminus of PTP1B with an allosteric inhibitor
- (2014) Navasona Krishnan et al. Nature Chemical Biology
- De Novo Mutations in Moderate or Severe Intellectual Disability
- (2014) Fadi F. Hamdan et al. PLoS Genetics
- The RASopathies
- (2013) Katherine A. Rauen Annual Review of Genomics and Human Genetics
- An MRAS, SHOC2, and SCRIB Complex Coordinates ERK Pathway Activation with Polarity and Tumorigenic Growth
- (2013) Lucy C. Young et al. MOLECULAR CELL
- Functional Integration of the Conserved Domains of Shoc2 Scaffold
- (2013) Myoungkun Jeoung et al. PLoS One
- Structural Biology of Arf and Rab GTPases’ Effector Recruitment and Specificity
- (2013) Amir R. Khan et al. STRUCTURE
- Challenges and Opportunities in the Development of Protein Phosphatase-Directed Therapeutics
- (2012) Sofie De Munter et al. ACS Chemical Biology
- Structural basis for protein phosphatase 1 regulation and specificity
- (2012) Wolfgang Peti et al. FEBS Journal
- Costello syndrome: a Ras/mitogen activated protein kinase pathway syndrome (rasopathy) resulting from HRAS germline mutations
- (2012) Karen W. Gripp et al. GENETICS IN MEDICINE
- SHOC2 and CRAF Mediate ERK1/2 Reactivation in Mutant NRAS-mediated Resistance to RAF Inhibitor
- (2012) Fred M. Kaplan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intrinsically disordered proteins: a 10-year recap
- (2012) Peter Tompa TRENDS IN BIOCHEMICAL SCIENCES
- Impaired Binding of 14-3-3 to C-RAF in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling
- (2010) M. Molzan et al. MOLECULAR AND CELLULAR BIOLOGY
- Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1)
- (2010) A. Mishra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The extended PP1 toolkit: designed to create specificity
- (2010) Mathieu Bollen et al. TRENDS IN BIOCHEMICAL SCIENCES
- Basis for the Isoform-specific Interaction of Myosin Phosphatase Subunits Protein Phosphatase 1c β and Myosin Phosphatase Targeting Subunit 1
- (2009) Elizabeth Scotto-Lavino et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair
- (2009) Viviana Cordeddu et al. NATURE GENETICS
- A Versatile Viral System for Expression and Depletion of Proteins in Mammalian Cells
- (2009) Eric Campeau et al. PLoS One
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