Cell and molecular biology of intervertebral disc degeneration: current understanding and implications for potential therapeutic strategies

Dual release of dexamethasone and TGF-β3 from polymeric microspheres for stem cell matrix accumulation in a rat disc degeneration model

(2013) Cheng-zhen Liang et al.   Acta Biomaterialia

Incidence and Risk Factors for Lumbar Degenerative Disc Disease in the United States Military 1999–2008

(2013) Andrew J. Schoenfeld et al.   MILITARY MEDICINE

Bioactive Factors in Platelet-Rich Plasma Obtained by Apheresis

(2013) Jan Philipp Krüger et al.   TRANSFUSION MEDICINE AND HEMOTHERAPY

Effect of autologous platelet-rich plasma-releasate on intervertebral disc degeneration in the rabbit anular puncture model: a preclinical study

(2012) Shuji Obata et al.   ARTHRITIS RESEARCH & THERAPY

Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc

(2012) Daisuke Sakai et al.   Nature Communications

Lentiviral shRNA silencing of CHOP inhibits apoptosis induced by cyclic stretch in rat annular cells and attenuates disc degeneration in the rats

(2011) Yue-Hui Zhang et al.   APOPTOSIS

Genetic susceptibility of intervertebral disc degeneration among young Finnish adults

(2011) Anthi Kelempisioti et al.   BMC Medical Genetics

TGF-β signaling plays an essential role in the growth and maintenance of intervertebral disc tissue

(2011) Hongting Jin et al.   FEBS LETTERS

Tissue Engineering of the Intervertebral Disc With Cultured Nucleus Pulposus Cells Using Atelocollagen Scaffold and Growth Factors

(2011) Kwang-Il Lee et al.   SPINE

Degeneration and regeneration of the intervertebral disc: lessons from development

(2010) L. J. Smith et al.   Disease Models & Mechanisms

Immunohistochemical identification of notochordal markers in cells in the aging human lumbar intervertebral disc

(2010) Christoph Weiler et al.   EUROPEAN SPINE JOURNAL

Debating the Value of Spine Surgery*

(2010) Edward N Hanley et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Multipotential Differentiation of Human Anulus Fibrosus Cells

(2010) Gang Feng et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Co-culture induces mesenchymal stem cell differentiation and modulation of the degenerate human nucleus pulposus cell phenotype

(2010) Sandra Strassburg et al.   Regenerative Medicine

Isolation and Characterization of Mesenchymal Stromal Cells From Human Degenerated Nucleus Pulposus

(2010) Juan F. Blanco et al.   SPINE

Notochordal cell conditioned medium stimulates mesenchymal stem cell differentiation toward a young nucleus pulposus phenotype

(2010) Casey L Korecki et al.   Stem Cell Research & Therapy

Enhanced differentiation of mesenchymal stem cells into NP-like cells via 3D co-culturing with mechanical stimulation

(2009) Dong Hwa Kim et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Association of the Tag SNPs in the HumanSKTGene (KIAA1217) With Lumbar Disc Herniation

(2009) Tatsuki Karasugi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Biologic Response of Human Intervertebral Disc Cells to Gene Therapy Cocktail

(2009) Seong-Hwan Moon et al.   SPINE

Identification of Cell Proliferation Zones, Progenitor Cells and a Potential Stem Cell Niche in the Intervertebral Disc Region

(2009) Helena B. Henriksson et al.   SPINE

Characterization of In Vivo Effects of Platelet-Rich Plasma and Biodegradable Gelatin Hydrogel Microspheres on Degenerated Intervertebral Discs

(2009) Kazuhide Sawamura et al.   TISSUE ENGINEERING PART A

Effect of small interference RNA (siRNA) for ADAMTS5 on intervertebral disc degeneration in the rabbit anular needle-puncture model

(2009) Shoji Seki et al.   ARTHRITIS RESEARCH & THERAPY

Vascular endothelial growth factor-A is a survival factor for nucleus pulposus cells in the intervertebral disc

(2008) Nobuyuki Fujita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: Implications for disk degeneration and chordoma formation

(2008) Kyung-Suk Choi et al.   DEVELOPMENTAL DYNAMICS

Stepwise reduction of functional spinal structures increase disc bulge and surface strains

(2008) Frank Heuer et al.   JOURNAL OF BIOMECHANICS

The pathophysiology of disc degeneration

(2008) A. G. Hadjipavlou et al.   JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME

The cellular pathobiology of the degenerate intervertebral disc and discogenic back pain

(2008) A. J. Freemont   RHEUMATOLOGY

Frequency-Dependent Behavior of the Intervertebral Disc in Response to Each of Six Degree of Freedom Dynamic Loading

(2008) John J. Costi et al.   SPINE

A systematic review of low back pain cost of illness studies in the United States and internationally

(2008) Simon Dagenais et al.   Spine Journal

The Twin Spine Study: Contributions to a changing view of disc degeneration†

(2008) Michele C. Battié et al.   Spine Journal

Feasibility of a stem cell therapy for intervertebral disc degeneration

(2007) Satoshi Sobajima et al.   Spine Journal