Prolyl-4-hydroxylase Domain Protein 2 Controls NF-κB/p65 Transactivation and Enhances the Catabolic Effects of Inflammatory Cytokines on Cells of the Nucleus Pulposus
出版年份 2015 全文链接
标题
Prolyl-4-hydroxylase Domain Protein 2 Controls NF-κB/p65 Transactivation and Enhances the Catabolic Effects of Inflammatory Cytokines on Cells of the Nucleus Pulposus
作者
关键词
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出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 290, Issue 11, Pages 7195-7207
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2015-01-30
DOI
10.1074/jbc.m114.611483
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- (2014) Xin Wang et al. AMERICAN JOURNAL OF PATHOLOGY
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- (2014) Demissew S. Mern et al. PLoS One
- EGLN3 Inhibition of NF- B Is Mediated by Prolyl Hydroxylase-Independent Inhibition of I B Kinase Ubiquitination
- (2013) J. Fu et al. MOLECULAR AND CELLULAR BIOLOGY
- Contribution of epithelial innate immunity to systemic protection afforded by prolyl hydroxylase inhibition in murine colitis
- (2013) S Keely et al. Mucosal Immunology
- A Combinatorial Relative Mass Value Evaluation of Endogenous Bioactive Proteins in Three-Dimensional Cultured Nucleus Pulposus Cells of Herniated Intervertebral Discs: Identification of Potential Target Proteins for Gene Therapeutic Approaches
- (2013) Demissew S. Mern et al. PLoS One
- Expression of Prolyl Hydroxylases (PHDs) Is Selectively Controlled by HIF-1 and HIF-2 Proteins in Nucleus Pulposus Cells of the Intervertebral Disc
- (2012) Nobuyuki Fujita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prolyl Hydroxylase 3 (PHD3) Modulates Catabolic Effects of Tumor Necrosis Factor-α (TNF-α) on Cells of the Nucleus Pulposus through Co-activation of Nuclear Factor κB (NF-κB)/p65 Signaling
- (2012) Nobuyuki Fujita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Oxygen sensing by the prolyl-4-hydroxylase PHD2 within the nuclear compartment and the influence of compartmentalisation on HIF-1 signalling
- (2012) F. K. Pientka et al. JOURNAL OF CELL SCIENCE
- TNF-α and IL-1β Promote a Disintegrin-like and Metalloprotease with Thrombospondin Type I Motif-5-mediated Aggrecan Degradation through Syndecan-4 in Intervertebral Disc
- (2011) Jianru Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc
- (2011) Nobuyuki Fujita et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Nuclear factor-κB2/p100 promotes endometrial carcinoma cell survival under hypoxia in a HIF-1α independent manner
- (2011) Andree Yeramian et al. LABORATORY INVESTIGATION
- The Hydroxylase Inhibitor Dimethyloxallyl Glycine Attenuates Endotoxic Shock Via Alternative Activation of Macrophages and IL-10 Production by B1 Cells
- (2011) Emily Hams et al. SHOCK
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- (2010) Jian Fu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HIF prolyl hydroxylase inhibition increases cell viability and potentiates dopamine release in dopaminergic cells
- (2010) Jens Leander Johansen et al. JOURNAL OF NEUROCHEMISTRY
- ADAMTS-5 and Intervertebral Disc Degeneration: The Results of Tissue Immunohistochemistry and In Vitro Cell Culture
- (2010) Chang-Qing Zhao et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Inhibition of Prolyl Hydroxylase Domain-Containing Protein Suppressed Lipopolysaccharide-Induced TNF-α Expression
- (2009) Kotaro Takeda et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Tumor Vasculature Is Regulated by PHD2-Mediated Angiogenesis and Bone Marrow-Derived Cell Recruitment
- (2009) Denise A. Chan et al. CANCER CELL
- A Feedback Loop Involving the Phd3 Prolyl Hydroxylase Tunes the Mammalian Hypoxic Response In Vivo
- (2009) Y. A. Minamishima et al. MOLECULAR AND CELLULAR BIOLOGY
- Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration
- (2009) S Jane Millward-Sadler et al. ARTHRITIS RESEARCH & THERAPY
- Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
- (2008) William G. Kaelin et al. MOLECULAR CELL
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