Small Molecule Inhibitors of HSF1-Activated Pathways as Potential Next-Generation Anticancer Therapeutics
出版年份 2018 全文链接
标题
Small Molecule Inhibitors of HSF1-Activated Pathways as Potential Next-Generation Anticancer Therapeutics
作者
关键词
-
出版物
MOLECULES
Volume 23, Issue 11, Pages 2757
出版商
MDPI AG
发表日期
2018-10-26
DOI
10.3390/molecules23112757
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic Target
- (2018) Jacqueline H.L. Fok et al. CLINICAL CANCER RESEARCH
- Design, synthesis, and biological evaluation of a series of resorcinol-based N -benzyl benzamide derivatives as potent Hsp90 inhibitors
- (2018) Sun You Park et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Discovery and optimization of cardenolides inhibiting HSF1 activation in human colon HCT-116 cancer cells
- (2018) Alina D. Nikotina et al. Oncotarget
- HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation
- (2018) Toshiki Kijima et al. Scientific Reports
- Regulation of the mammalian heat shock factor 1
- (2017) Sharadha Dayalan Naidu et al. FEBS Journal
- Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic Approach
- (2017) et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Ugi Reaction-Derived α-Acyl Aminocarboxamides Bind to Phosphatidylinositol 3-Kinase-Related Kinases, Inhibit HSF1-Dependent Heat Shock Response, and Induce Apoptosis in Multiple Myeloma Cells
- (2017) Matthias Bach et al. JOURNAL OF MEDICINAL CHEMISTRY
- A Pre-Clinical Evaluation of Minnelide in Treating Melanoma
- (2017) Vrishketan Sethi et al. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
- Heat Shock Protein-Inducing Property of Diarylheptanoid Containing Chalcone Moiety from Alpinia katsumadai
- (2017) Joo-Won Nam et al. MOLECULES
- Regulation of heat shock transcription factors and their roles in physiology and disease
- (2017) Rocio Gomez-Pastor et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- New inhibitor targeting human transcription factor HSF1: effects on the heat shock response and tumor cell survival
- (2017) Nuria Vilaboa et al. NUCLEIC ACIDS RESEARCH
- Rethinking HSF1 in Stress, Development, and Organismal Health
- (2017) Jian Li et al. TRENDS IN CELL BIOLOGY
- Selective killing of cancer cells by small molecules targeting heat shock stress response
- (2016) Daniel Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Targeting the entry region of Hsp90's ATP binding pocket with a novel 6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl amide
- (2016) Ju Hui Jeong et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen
- (2016) Matthew D. Cheeseman et al. JOURNAL OF MEDICINAL CHEMISTRY
- Heat Shock Factor 1: From Fire Chief to Crowd-Control Specialist
- (2016) Catherine G. Triandafillou et al. MOLECULAR CELL
- Structure of human heat-shock transcription factor 1 in complex with DNA
- (2016) Tobias Neudegger et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- HSF1: Guardian of Proteostasis in Cancer
- (2016) Chengkai Dai et al. TRENDS IN CELL BIOLOGY
- Discovery of 4,6-disubstituted pyrimidines as potent inhibitors of the heat shock factor 1 (HSF1) stress pathway and CDK9
- (2016) Carl S. Rye et al. MedChemComm
- Structure of human heat-shock transcription factor 1 in complex with DNA
- (2016) Tobias Neudegger et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Fisetin, a dietary flavonoid, induces apoptosis of cancer cells by inhibiting HSF1 activity through blocking its binding to the hsp70 promoter
- (2015) J. A. Kim et al. CARCINOGENESIS
- Heat shock factor 1 is a potent therapeutic target for enhancing the efficacy of treatments for multiple myeloma with adverse prognosis
- (2015) Sophie Bustany et al. Journal of Hematology & Oncology
- When Cancer Fights Back: Multiple Myeloma, Proteasome Inhibition, and the Heat-Shock Response
- (2015) S. P. Shah et al. MOLECULAR CANCER RESEARCH
- Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia
- (2015) Siddhartha Ganguly et al. Oncotarget
- Pleiotropic Role of HSF1 in Neoplastic Transformation
- (2014) Natalia Vydra et al. CURRENT CANCER DRUG TARGETS
- 2,4-Bis(4-hydroxybenzyl)phenol Inhibits Heat Shock Transcription Factor 1 and Sensitizes Lung Cancer Cells to Conventional Anticancer Modalities
- (2014) Taesook Yoon et al. JOURNAL OF NATURAL PRODUCTS
- Targeting the hydrophobic region of Hsp90’s ATP binding pocket with novel 1,3,5-triazines
- (2013) Taeho Lee et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Discovery of hybrid Hsp90 inhibitors and their anti-neoplastic effects against gefitinib-resistant non-small cell lung cancer (NSCLC)
- (2013) Chul-Ho Jeong et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Heat Shock Factor 1 (HSF1) Controls Chemoresistance and Autophagy through Transcriptional Regulation of Autophagy-related Protein 7 (ATG7)
- (2013) Shruti Desai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Natural Compound Cantharidin Induces Cancer Cell Death through Inhibition of Heat Shock Protein 70 (HSP70) and Bcl-2-associated Athanogene Domain 3 (BAG3) Expression by Blocking Heat Shock Factor 1 (HSF1) Binding to Promoters
- (2013) Joo Ae Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tight Coordination of Protein Translation and HSF1 Activation Supports the Anabolic Malignant State
- (2013) S. Santagata et al. SCIENCE
- Small Molecule Activators of the Heat Shock Response: Chemical Properties, Molecular Targets, and Therapeutic Promise
- (2012) James D. West et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Post-Translational Modification of Human Heat Shock Factors and Their Functions: A Recent Update by Proteomic Approach
- (2012) Yan-Ming Xu et al. JOURNAL OF PROTEOME RESEARCH
- Triptolide: structural modifications, structure–activity relationships, bioactivities, clinical development and mechanisms
- (2012) Zhao-Li Zhou et al. NATURAL PRODUCT REPORTS
- A Preclinical Evaluation of Minnelide as a Therapeutic Agent Against Pancreatic Cancer
- (2012) R. Chugh et al. Science Translational Medicine
- Implication of Heat Shock Factors in Tumorigenesis: Therapeutical Potential
- (2011) Aurelie De Thonel et al. Cancers
- KRIBB11 Inhibits HSP70 Synthesis through Inhibition of Heat Shock Factor 1 Function by Impairing the Recruitment of Positive Transcription Elongation Factor b to thehsp70Promoter
- (2010) Young Ju Yoon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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