Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma

ApoE facilitates the microglial response to amyloid plaque pathology

(2018) Jason D. Ulrich et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD163+ macrophages infiltrate axon bundles of postmortem optic nerves with glaucoma

(2018) Milica A. Margeta et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Neuroinflammation in glaucoma: A new opportunity

(2017) Pete A. Williams et al.   EXPERIMENTAL EYE RESEARCH

GlyCAM1 negatively regulates monocyte entry into the optic nerve head and contributes to radiation-based protection in glaucoma

(2017) Pete A. Williams et al.   Journal of Neuroinflammation

Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective

(2017) Jeffrey M. Harder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vitamin B 3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice

(2017) Pete A. Williams et al.   SCIENCE

Metabolic Vulnerability in the Neurodegenerative Disease Glaucoma

(2017) Denise M. Inman et al.   Frontiers in Neuroscience

Nicotinamide and WLDS Act Together to Prevent Neurodegeneration in Glaucoma

(2017) Pete A. Williams et al.   Frontiers in Neuroscience

Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma

(2016) Pete A. Williams et al.   Molecular Neurodegeneration

Restored expression of vitamin D receptor and sensitivity to 1,25-dihydroxyvitamin D3 in response to disrupted fusion FOP2–FGFR1 gene in acute myeloid leukemia cells

(2016) Aleksandra Marchwicka et al.   Cell and Bioscience

Platelet Activation: The Mechanisms and Potential Biomarkers

(2016) Seong-Hoon Yun et al.   Biomed Research International

Visual and Ocular Manifestations of Alzheimer’s Disease and Their Use as Biomarkers for Diagnosis and Progression

(2016) Fatimah Zara Javaid et al.   Frontiers in Neurology

mTOR activation is a biomarker and a central pathway to autoimmune disorders, cancer, obesity, and aging

(2015) Andras Perl   Annals of the New York Academy of Sciences

Glial cell interactions and glaucoma

(2015) Rachel S. Chong et al.   CURRENT OPINION IN OPHTHALMOLOGY

Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities

(2015) Kimberly A. Fernandes et al.   EXPERIMENTAL EYE RESEARCH

Soluble Tumor Necrosis Factor Alpha Promotes Retinal Ganglion Cell Death in Glaucoma via Calcium-Permeable AMPA Receptor Activation

(2015) J. L. Cueva Vargas et al.   JOURNAL OF NEUROSCIENCE

Automatic Counting of Microglial Cells in Healthy and Glaucomatous Mouse Retinas

(2015) Pablo de Gracia et al.   PLoS One

Aspirin and P2Y12 Inhibitors in platelet-mediated activation of neutrophils and monocytes

(2015) Waltraud Schrottmaier et al.   THROMBOSIS AND HAEMOSTASIS

Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis

(2015) Inge R Holtman et al.   Acta Neuropathologica Communications

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Decorin Mimic Regulates Platelet-Derived Growth Factor and Interferon-γ Stimulation of Vascular Smooth Muscle Cells

(2014) Rebecca A. Scott et al.   BIOMACROMOLECULES

Macromolecular Approaches to Prevent Thrombosis and Intimal Hyperplasia Following Percutaneous Coronary Intervention

(2014) Rebecca A. Scott et al.   BIOMACROMOLECULES

Tumor necrosis factor alpha has an early protective effect on retinal ganglion cells after optic nerve crush

(2014) Caitlin E Mac Nair et al.   Journal of Neuroinflammation

Combinatorial targeting of early pathways profoundly inhibits neurodegeneration in a mouse model of glaucoma

(2014) Gareth R. Howell et al.   NEUROBIOLOGY OF DISEASE

Global Prevalence of Glaucoma and Projections of Glaucoma Burden through 2040

(2014) Yih-Chung Tham et al.   OPHTHALMOLOGY

The Complex Role of Neuroinflammation in Glaucoma

(2014) I. Soto et al.   Cold Spring Harbor Perspectives in Medicine

Mechanisms Regulating Endothelial Permeability

(2014) Sukriti Sukriti et al.   Pulmonary Circulation

Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice

(2013) Gareth R Howell et al.   Journal of Neuroinflammation

Baseline Gene Expression Signatures in Monocytes from Multiple Sclerosis Patients Treated with Interferon-beta

(2013) Marta F. Bustamante et al.   PLoS One

Decorin Mimic Inhibits Vascular Smooth Muscle Proliferation and Migration

(2013) Rebecca A. Scott et al.   PLoS One

PERK/eIF2  signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS

(2013) K. M. Rouschop et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repair of astrocytes, blood vessels, and myelin in the injured brain: possible roles of blood monocytes

(2013) Hey-Kyeong Jeong et al.   Molecular Brain

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Brain Inflammation and Microglia: Facts and Misconceptions

(2013) Hey-Kyeong Jeong et al.   Experimental Neurobiology

Under Pressure: Cellular and Molecular Responses During Glaucoma, a Common Neurodegeneration with Axonopathy

(2012) Robert W. Nickells et al.   Annual Review of Neuroscience

Platelets and platelet-like particles mediate intercellular RNA transfer

(2012) A. Risitano et al.   BLOOD

Platelets can enhance vascular permeability

(2012) N. Cloutier et al.   BLOOD

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

Optic Disc Fluorescein Leakage and Intraocular Pressure in Primary Open-Angle Glaucoma

(2012) Niklas Plange et al.   CURRENT EYE RESEARCH

Immune regulation toward immunomodulation for neuroprotection in glaucoma

(2012) Gülgün Tezel   CURRENT OPINION IN PHARMACOLOGY

Oxidative stress and mitochondrial dysfunction in glaucoma

(2012) Vicki Chrysostomou et al.   CURRENT OPINION IN PHARMACOLOGY

Eukaryotic Initiation Factor 2 (eIF2) Signaling Regulates Proinflammatory Cytokine Expression and Bacterial Invasion

(2012) Niraj Shrestha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma

(2012) Gareth R. Howell et al.   JOURNAL OF CLINICAL INVESTIGATION

MATS: a Bayesian framework for flexible detection of differential alternative splicing from RNA-Seq data

(2012) Shihao Shen et al.   NUCLEIC ACIDS RESEARCH

Early Reduction of Microglia Activation by Irradiation in a Model of Chronic Glaucoma

(2012) Alejandra Bosco et al.   PLoS One

Multicolor flow cytometry for evaluation of platelet surface antigens and activation markers

(2012) Jeroen F. van Velzen et al.   THROMBOSIS RESEARCH

BamTools: a C++ API and toolkit for analyzing and managing BAM files

(2011) D. W. Barnett et al.   BIOINFORMATICS

The inhibition of platelet adhesion and activation on collagen during balloon angioplasty by collagen-binding peptidoglycans

(2011) John E. Paderi et al.   BIOMATERIALS

Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma

(2011) Gareth R. Howell et al.   JOURNAL OF CLINICAL INVESTIGATION

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Collagen-Binding Peptidoglycans Inhibit MMP Mediated Collagen Degradation and Reduce Dermal Scarring

(2011) Kate Stuart et al.   PLoS One

Monocyte-Platelet Interaction Induces a Pro-Inflammatory Phenotype in Circulating Monocytes

(2011) Gabriella Passacquale et al.   PLoS One

Myelination transition zone astrocytes are constitutively phagocytic and have synuclein dependent reactivity in glaucoma

(2011) J. V. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of Synapse and Dendrite Maintenance and Their Disruption in Psychiatric and Neurodegenerative Disorders

(2010) Yu-Chih Lin et al.   Annual Review of Neuroscience

Early microglia activation in a mouse model of chronic glaucoma

(2010) Alejandra Bosco et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Fluorescein leakage of the optic disc: time course in primary open-angle glaucoma

(2010) Niklas Plange et al.   OPHTHALMIC AND PHYSIOLOGICAL OPTICS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Fibrinogen signal transduction in the nervous system

(2009) J. K. RYU et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Design of a Synthetic Collagen-Binding Peptidoglycan that Modulates Collagen Fibrillogenesis

(2008) John E. Paderi et al.   BIOMACROMOLECULES

GpnmbR150X allele must be present in bone marrow derived cells to mediate DBA/2J glaucoma

(2008) Michael G Anderson et al.   BMC GENETICS

TheWldSgene delays axonal but not somatic degeneration in a rat glaucoma model

(2008) Bogdan Beirowski et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Role of platelet-derived growth factors in physiology and medicine

(2008) J. Andrae et al.   GENES & DEVELOPMENT

Retinal Ganglion Cells Downregulate Gene Expression and Lose Their Axons within the Optic Nerve Head in a Mouse Glaucoma Model

(2008) I. Soto et al.   JOURNAL OF NEUROSCIENCE

DiRE: identifying distant regulatory elements of co-expressed genes

(2008) V. Gotea et al.   NUCLEIC ACIDS RESEARCH

Comprehensive Dissection of PDGF-PDGFR Signaling Pathways in PDGFR Genetically Defined Cells

(2008) Erxi Wu et al.   PLoS One