Nicotinamide and WLDS Act Together to Prevent Neurodegeneration in Glaucoma

Metabotropic glutamate receptors and neurodegenerative diseases

(2017) Fabiola M. Ribeiro et al.   PHARMACOLOGICAL RESEARCH

Vitamin B 3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice

(2017) Pete A. Williams et al.   SCIENCE

Differential expression of sema3A and sema7A in a murine model of multiple sclerosis: Implications for a therapeutic design

(2016) Ana Gutiérrez-Franco et al.   CLINICAL IMMUNOLOGY

Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma

(2016) Pete A. Williams et al.   Molecular Neurodegeneration

Electrophysiological assessment of retinal ganglion cell function

(2015) Vittorio Porciatti   EXPERIMENTAL EYE RESEARCH

SEMA4D compromises blood–brain barrier, activates microglia, and inhibits remyelination in neurodegenerative disease

(2015) Ernest S. Smith et al.   NEUROBIOLOGY OF DISEASE

Axon degeneration and PGC-1 -mediated protection in a zebrafish model of  -synuclein toxicity

(2014) K. C. O'Donnell et al.   Disease Models & Mechanisms

Ryanodine receptors: physiological function and deregulation in Alzheimer disease

(2014) Dolores Del Prete et al.   Molecular Neurodegeneration

LKB1 and AMPK regulate synaptic remodeling in old age

(2014) Melanie A Samuel et al.   NATURE NEUROSCIENCE

Mislocalization of neuronal mitochondria reveals regulation of Wallerian degeneration and NMNAT/WLDS-mediated axon protection independent of axonal mitochondria

(2013) Brandon M. Kitay et al.   HUMAN MOLECULAR GENETICS

WldS and PGC-1  Regulate Mitochondrial Transport and Oxidation State after Axonal Injury

(2013) K. C. O'Donnell et al.   JOURNAL OF NEUROSCIENCE

Retinal Ganglion Cell Dendritic Atrophy in DBA/2J Glaucoma

(2013) Pete A. Williams et al.   PLoS One

Under Pressure: Cellular and Molecular Responses During Glaucoma, a Common Neurodegeneration with Axonopathy

(2012) Robert W. Nickells et al.   Annual Review of Neuroscience

Opa1 is essential for retinal ganglion cell synaptic architecture and connectivity

(2012) Pete A. Williams et al.   BRAIN

WldS Prevents Axon Degeneration through Increased Mitochondrial Flux and Enhanced Mitochondrial Ca2+ Buffering

(2012) Michelle A. Avery et al.   CURRENT BIOLOGY

WldS but not Nmnat1 protects dopaminergic neurites from MPP+ neurotoxicity

(2012) Jo Ann V Antenor-Dorsey et al.   Molecular Neurodegeneration

New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs

(2012) Bryan A. Gibson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Eph receptors at synapses: Implications in neurodegenerative diseases

(2011) Yu Chen et al.   CELLULAR SIGNALLING

WldS Enhances Insulin Transcription and Secretion via a SIRT1-Dependent Pathway and Improves Glucose Homeostasis

(2011) J. Wu et al.   DIABETES

Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma

(2011) Gareth R. Howell et al.   JOURNAL OF CLINICAL INVESTIGATION

Wallerian Degeneration, WldS, and Nmnat

(2010) Michael P. Coleman et al.   Annual Review of Neuroscience

Early microglia activation in a mouse model of chronic glaucoma

(2010) Alejandra Bosco et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Semaphorin function in neural plasticity and disease

(2009) R Jeroen Pasterkamp et al.   CURRENT OPINION IN NEUROBIOLOGY

Non-Nuclear WldS Determines Its Neuroprotective Efficacy for Axons and Synapses In Vivo

(2009) B. Beirowski et al.   JOURNAL OF NEUROSCIENCE

Transgenic Mice Expressing the Nmnat1 Protein Manifest Robust Delay in Axonal Degeneration In Vivo

(2009) Y. Sasaki et al.   JOURNAL OF NEUROSCIENCE

TheWldSgene delays axonal but not somatic degeneration in a rat glaucoma model

(2008) Bogdan Beirowski et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration

(2008) R. Grace Zhai et al.   NATURE