标题
ApoE facilitates the microglial response to amyloid plaque pathology
作者
关键词
-
出版物
JOURNAL OF EXPERIMENTAL MEDICINE
Volume 215, Issue 4, Pages 1047-1058
出版商
Rockefeller University Press
发表日期
2018-02-26
DOI
10.1084/jem.20171265
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Apolipoprotein E, Receptors, and Modulation of Alzheimer’s Disease
- (2018) Na Zhao et al. BIOLOGICAL PSYCHIATRY
- The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
- (2017) Susanne Krasemann et al. IMMUNITY
- Apolipoprotein E and Alzheimer’s disease: the influence of apolipoprotein E on amyloid-β and other amyloidogenic proteins
- (2017) Tien-Phat V. Huynh et al. JOURNAL OF LIPID RESEARCH
- ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy
- (2017) Yang Shi et al. NATURE
- Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis
- (2017) Tien-Phat V. Huynh et al. NEURON
- ApoE4 Accelerates Early Seeding of Amyloid Pathology
- (2017) Chia-Chen Liu et al. NEURON
- TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques
- (2016) Yaming Wang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease
- (2016) Taylor R. Jay et al. JOURNAL OF NEUROSCIENCE
- TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy
- (2016) Peng Yuan et al. NEURON
- TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia
- (2016) Felix L. Yeh et al. NEURON
- Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes
- (2016) Won-Suk Chung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Untangling the brain’s neuroinflammatory and neurodegenerative transcriptional responses
- (2016) Karpagam Srinivasan et al. Nature Communications
- TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
- (2015) Yaming Wang et al. CELL
- Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)
- (2015) Yuka Atagi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Innate immunity in Alzheimer's disease
- (2015) Michael T Heneka et al. NATURE IMMUNOLOGY
- Neutrophils promote Alzheimer's disease–like pathology and cognitive decline via LFA-1 integrin
- (2015) Elena Zenaro et al. NATURE MEDICINE
- Three dimensions of the amyloid hypothesis: time, space and 'wingmen'
- (2015) Erik S Musiek et al. NATURE NEUROSCIENCE
- Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques
- (2015) Carlo Condello et al. Nature Communications
- Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice
- (2014) Oleg Butovsky et al. ANNALS OF NEUROLOGY
- Apolipoprotein E mediation of neuro-inflammation in a murine model of multiple sclerosis
- (2014) Soomin Shin et al. JOURNAL OF NEUROIMMUNOLOGY
- Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition
- (2014) Gustavo A Rodriguez et al. Journal of Neuroinflammation
- Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2
- (2014) Jason D Ulrich et al. Molecular Neurodegeneration
- Single App knock-in mouse models of Alzheimer's disease
- (2014) Takashi Saito et al. NATURE NEUROSCIENCE
- Multimodal fluorescence microscopy of prion strain specific PrP deposits stained by thiophene-based amyloid ligands
- (2014) Karin Magnusson et al. Prion
- Evidence for Age-Dependent in Vivo Conformational Rearrangement within Aβ Amyloid Deposits
- (2013) Sofie Nyström et al. ACS Chemical Biology
- Luminescent Conjugated Oligothiophenes for Sensitive Fluorescent Assignment of Protein Inclusion Bodies
- (2013) Therése Klingstedt et al. CHEMBIOCHEM
- Differential Relationships of Reactive Astrocytes and Microglia to Fibrillar Amyloid Deposits in Alzheimer Disease
- (2013) Alberto Serrano-Pozo et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Identification of a unique TGF-β–dependent molecular and functional signature in microglia
- (2013) Oleg Butovsky et al. NATURE NEUROSCIENCE
- Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta
- (2013) Ana Griciuc et al. NEURON
- Microglia: Scapegoat, Saboteur, or Something Else?
- (2013) A. Aguzzi et al. SCIENCE
- Apolipoprotein E controls cerebrovascular integrity via cyclophilin A
- (2012) Robert D. Bell et al. NATURE
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
- (2011) Adam C Naj et al. NATURE GENETICS
- Synthesis of a library of oligothiophenes and their utilization as fluorescent ligands for spectral assignment of protein aggregates
- (2011) Therése Klingstedt et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Lack of LDL Receptor Enhances Amyloid Deposition and Decreases Glial Response in an Alzheimer's Disease Mouse Model
- (2011) Loukia Katsouri et al. PLoS One
- apoE isoform–specific disruption of amyloid β peptide clearance from mouse brain
- (2008) Rashid Deane et al. JOURNAL OF CLINICAL INVESTIGATION
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