Environmental stresses induce karyotypic instability in colorectal cancer cells

Cancer: a CINful evolution

(2018) Altea Targa et al.   CURRENT OPINION IN CELL BIOLOGY

Transcriptome analysis of tetraploid cells identifies cyclin D2 as a facilitator of adaptation to genome doubling in the presence of p53

(2016) Tamara A. Potapova et al.   MOLECULAR BIOLOGY OF THE CELL

Regional hyperthermia combined with chemotherapy in paediatric, adolescent and young adult patients: current and future perspectives

(2016) Georg Seifert et al.   Radiation Oncology

Mcl-1 dynamics influence mitotic slippage and death in mitosis

(2016) Olivia Sloss et al.   Oncotarget

Selective advantage of trisomic human cells cultured in non-standard conditions

(2016) Samuel D. Rutledge et al.   Scientific Reports

Chromosomal instability, tolerance of mitotic errors and multidrug resistance are promoted by tetraploidization in human cells

(2015) Anastasia Y Kuznetsova et al.   CELL CYCLE

The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics

(2015) Andrea Musacchio   CURRENT BIOLOGY

Hyperthermia-related clinical trials on cancer treatment within the ClinicalTrials.gov registry

(2015) Nikola Cihoric et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Oxidative stress promotes pathologic polyploidization in nonalcoholic fatty liver disease

(2015) Géraldine Gentric et al.   JOURNAL OF CLINICAL INVESTIGATION

Centrosome-intrinsic mechanisms modulate centrosome integrity during fever

(2015) Anastassiia Vertii et al.   MOLECULAR BIOLOGY OF THE CELL

Revisiting tumour aneuploidy — the place of ploidy assessment in the molecular era

(2015) Håvard E. Danielsen et al.   Nature Reviews Clinical Oncology

Aneuploidy and chromosomal instability in cancer: a jackpot to chaos

(2015) Maybelline Giam et al.   Cell Division

Chromosome mis-segregation and cytokinesis failure in trisomic human cells

(2015) Joshua M Nicholson et al.   eLife

Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directions

(2014) Naveen S. Vasudev et al.   ANGIOGENESIS

Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C

(2014) Katharine L. Sackton et al.   NATURE

Aneuploidy induces profound changes in gene expression, proliferation and tumorigenicity of human pluripotent stem cells

(2014) Uri Ben-David et al.   Nature Communications

DNA-Damage Response during Mitosis Induces Whole-Chromosome Missegregation

(2014) S. F. Bakhoum et al.   Cancer Discovery

Cumulative Haploinsufficiency and Triplosensitivity Drive Aneuploidy Patterns and Shape the Cancer Genome

(2013) Teresa Davoli et al.   CELL

The causes and consequences of genetic heterogeneity in cancer evolution

(2013) Rebecca A. Burrell et al.   NATURE

Whole chromosome aneuploidy: Big mutations drive adaptation by phenotypic leap

(2012) Guangbo Chen et al.   BIOESSAYS

Pericyte Depletion Results in Hypoxia-Associated Epithelial-to-Mesenchymal Transition and Metastasis Mediated by Met Signaling Pathway

(2012) Vesselina G. Cooke et al.   CANCER CELL

VEGF Inhibits Tumor Cell Invasion and Mesenchymal Transition through a MET/VEGFR2 Complex

(2012) Kan V. Lu et al.   CANCER CELL

CENP-E–dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint

(2012) Yige Guo et al.   JOURNAL OF CELL BIOLOGY

Dual effect of heat shock on DNA replication and genome integrity

(2012) Artem K. Velichko et al.   MOLECULAR BIOLOGY OF THE CELL

Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy

(2012) Guangbo Chen et al.   NATURE

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Recurrent Hemizygous Deletions in Cancers May Optimize Proliferative Potential

(2012) N. L. Solimini et al.   SCIENCE

Rapid aneuploidy diagnosis of trisomy 18 by array comparative genomic hybridization using uncultured amniocytes in a pregnancy with fetal arachnoid cyst detected in late second trimester

(2012) Chih-Ping Chen et al.   Taiwanese Journal of Obstetrics & Gynecology

Suppression of Tumor Invasion and Metastasis by Concurrent Inhibition of c-Met and VEGF Signaling in Pancreatic Neuroendocrine Tumors

(2012) Barbara Sennino et al.   Cancer Discovery

Karyotypic Determinants of Chromosome Instability in Aneuploid Budding Yeast

(2012) Jin Zhu et al.   PLoS Genetics

Chromosomal Instability Confers Intrinsic Multidrug Resistance

(2011) A. J. X. Lee et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Aneuploidy Drives Genomic Instability in Yeast

(2011) J. M. Sheltzer et al.   SCIENCE

Stress Alters Rates and Types of Loss of Heterozygosity in Candida albicans

(2011) A. Forche et al.   mBio

Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling

(2010) T. van Harn et al.   GENES & DEVELOPMENT

Loss of pRB causes centromere dysfunction and chromosomal instability

(2010) A. L. Manning et al.   GENES & DEVELOPMENT

Hsp90–Sgt1 and Skp1 target human Mis12 complexes to ensure efficient formation of kinetochore–microtubule binding sites

(2010) Alexander E. Davies et al.   JOURNAL OF CELL BIOLOGY

Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal

(2010) Rocio Sotillo et al.   NATURE

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

Hepatitis C Virus Causes Uncoupling of Mitotic Checkpoint and Chromosomal Polyploidy through the Rb Pathway

(2009) K. Machida et al.   JOURNAL OF VIROLOGY

A mechanism linking extra centrosomes to chromosomal instability

(2009) Neil J. Ganem et al.   NATURE

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

(2009) Andrew J. Holland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Multipolar Spindle Pole Coalescence Is a Major Source of Kinetochore Mis-Attachment and Chromosome Mis-Segregation in Cancer Cells

(2009) William T. Silkworth et al.   PLoS One

Chromosomal instability determines taxane response

(2009) C. Swanton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Cells Display Profound Intra- and Interline Variation following Prolonged Exposure to Antimitotic Drugs

(2008) Karen E. Gascoigne et al.   CANCER CELL

Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit

(2008) Haomin Huang et al.   JOURNAL OF CELL BIOLOGY

Genome stability is ensured by temporal control of kinetochore–microtubule dynamics

(2008) Samuel F. Bakhoum et al.   NATURE CELL BIOLOGY