标题
Aneuploidy and chromosomal instability in cancer: a jackpot to chaos
作者
关键词
Aneuploidy, Chromosome instability, DNA damage, Cancer evolution, Oncogene, Tumor suppressor
出版物
Cell Division
Volume 10, Issue 1, Pages -
出版商
Springer Nature
发表日期
2015-05-19
DOI
10.1186/s13008-015-0009-7
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Mitotic entry in the presence of DNA damage is a widespread property of aneuploidy in yeast
- (2015) Heidi M. Blank et al. MOLECULAR BIOLOGY OF THE CELL
- Chromosome mis-segregation and cytokinesis failure in trisomic human cells
- (2015) Joshua M Nicholson et al. eLife
- COSMIC: exploring the world's knowledge of somatic mutations in human cancer
- (2014) Simon A. Forbes et al. NUCLEIC ACIDS RESEARCH
- Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress
- (2014) Floris Foijer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aneuploidy induces profound changes in gene expression, proliferation and tumorigenicity of human pluripotent stem cells
- (2014) Uri Ben-David et al. Nature Communications
- DNA-Damage Response during Mitosis Induces Whole-Chromosome Missegregation
- (2014) S. F. Bakhoum et al. Cancer Discovery
- Aneuploidy in pluripotent stem cells and implications for cancerous transformation
- (2014) Jie Na et al. Protein & Cell
- Time-Lapse Analysis of Human Embryonic Stem Cells Reveals Multiple Bottlenecks Restricting Colony Formation and Their Relief upon Culture Adaptation
- (2014) Ivana Barbaric et al. Stem Cell Reports
- Causes of Genome Instability
- (2013) Andrés Aguilera et al. Annual Review of Genetics
- Aneuploidy and chromosomal instability: a vicious cycle driving cellular evolution and cancer genome chaos
- (2013) Tamara A. Potapova et al. CANCER AND METASTASIS REVIEWS
- A single extra copy of Dscr1 improves survival of mice developing spontaneous lung tumors through suppression of tumor angiogenesis
- (2013) Jimin Shin et al. CANCER LETTERS
- Cumulative Haploinsufficiency and Triplosensitivity Drive Aneuploidy Patterns and Shape the Cancer Genome
- (2013) Teresa Davoli et al. CELL
- Replication stress links structural and numerical cancer chromosomal instability
- (2013) Rebecca A. Burrell et al. NATURE
- The cancer biology of whole-chromosome instability
- (2013) P H G Duijf et al. ONCOGENE
- Whole chromosome gain does not in itself confer cancer-like chromosomal instability
- (2013) A. Valind et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors
- (2013) A. D. Silk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cancer Genome Landscapes
- (2013) B. Vogelstein et al. SCIENCE
- Karyotypic changes as drivers and catalyzers of cellular evolvability: A perspective from non-pathogenic yeasts
- (2013) Giulia Rancati et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- p21 Both Attenuates and Drives Senescence and Aging in BubR1 Progeroid Mice
- (2013) Darren J. Baker et al. Cell Reports
- Cancer Karyotypes: Survival of the Fittest
- (2013) Joshua M. Nicholson et al. Frontiers in Oncology
- Multi-Layered Cancer Chromosomal Instability Phenotype
- (2013) Anna V. Roschke et al. Frontiers in Oncology
- New Insights into the Troubles of Aneuploidy
- (2012) Jake J. Siegel et al. Annual Review of Cell and Developmental Biology
- Whole chromosome aneuploidy: Big mutations drive adaptation by phenotypic leap
- (2012) Guangbo Chen et al. BIOESSAYS
- The Spindle Assembly Checkpoint
- (2012) Pablo Lara-Gonzalez et al. CURRENT BIOLOGY
- Cancer chromosomal instability: therapeutic and diagnostic challenges
- (2012) Nicholas McGranahan et al. EMBO REPORTS
- Mitosis-Specific Regulation of Nuclear Transport by the Spindle Assembly Checkpoint Protein Mad1p
- (2012) Lucas V. Cairo et al. MOLECULAR CELL
- Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells
- (2012) Silvia Stingele et al. Molecular Systems Biology
- DNA breaks and chromosome pulverization from errors in mitosis
- (2012) Karen Crasta et al. NATURE
- Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan
- (2012) Darren J. Baker et al. NATURE CELL BIOLOGY
- Human aneuploidy: mechanisms and new insights into an age-old problem
- (2012) So I. Nagaoka et al. NATURE REVIEWS GENETICS
- Aneuploidy-induced delaminating cells drive tumorigenesis in Drosophila epithelia
- (2012) A. Dekanty et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcriptional consequences of aneuploidy
- (2012) J. M. Sheltzer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Karyotypic Determinants of Chromosome Instability in Aneuploid Budding Yeast
- (2012) Jin Zhu et al. PLoS Genetics
- Molecular lesions in childhood and adult acute megakaryoblastic leukaemia
- (2011) Asahito Hama et al. BRITISH JOURNAL OF HAEMATOLOGY
- Increased Survival following Tumorigenesis in Ts65Dn Mice That Model Down Syndrome
- (2011) A. Yang et al. CANCER RESEARCH
- Paradoxical Relationship between Chromosomal Instability and Survival Outcome in Cancer
- (2011) N. J. Birkbak et al. CANCER RESEARCH
- Chromosomal Instability Confers Intrinsic Multidrug Resistance
- (2011) A. J. X. Lee et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Sporadic Aneuploidy in PHA-Stimulated Lymphocytes of Trisomies 21, 18, and 13
- (2011) O. Reish et al. CYTOGENETIC AND GENOME RESEARCH
- Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation
- (2011) Robin M. Ricke et al. JOURNAL OF CELL BIOLOGY
- Mutations in CEP57 cause mosaic variegated aneuploidy syndrome
- (2011) Katie Snape et al. NATURE GENETICS
- Dysregulation of Gene Expression in the Artificial Human Trisomy Cells of Chromosome 8 Associated with Transformed Cell Phenotypes
- (2011) Hisakatsu Nawata et al. PLoS One
- Chromosome Segregation Errors as a Cause of DNA Damage and Structural Chromosome Aberrations
- (2011) A. Janssen et al. SCIENCE
- Aneuploidy Drives Genomic Instability in Yeast
- (2011) J. M. Sheltzer et al. SCIENCE
- Molecular Causes for BUBR1 Dysfunction in the Human Cancer Predisposition Syndrome Mosaic Variegated Aneuploidy
- (2010) Saskia J.E. Suijkerbuijk et al. CANCER RESEARCH
- Identification of Aneuploidy-Tolerating Mutations
- (2010) Eduardo M. Torres et al. CELL
- Mechanisms of Chromosomal Instability
- (2010) Sarah L. Thompson et al. CURRENT BIOLOGY
- Dr Jekyll and Mr Hyde: role of aneuploidy in cellular adaptation and cancer
- (2010) Norman Pavelka et al. CURRENT OPINION IN CELL BIOLOGY
- Somatic mutations in cancer prognosis and prediction: lessons from TP53 and EGFR genes
- (2010) Magali Olivier et al. CURRENT OPINION IN ONCOLOGY
- miR-125b-2 is a potential oncomiR on human chromosome 21 in megakaryoblastic leukemia
- (2010) J.-H. Klusmann et al. GENES & DEVELOPMENT
- Proliferation of aneuploid human cells is limited by a p53-dependent mechanism
- (2010) Sarah L. Thompson et al. JOURNAL OF CELL BIOLOGY
- The role of genetic diversity in cancer
- (2010) Lauren M.F. Merlo et al. JOURNAL OF CLINICAL INVESTIGATION
- Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal
- (2010) Rocio Sotillo et al. NATURE
- The ploidy conveyor of mature hepatocytes as a source of genetic variation
- (2010) Andrew W. Duncan et al. NATURE
- Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast
- (2010) Norman Pavelka et al. NATURE
- Genomic instability — an evolving hallmark of cancer
- (2010) Simona Negrini et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis
- (2010) M. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ETS2 and ERG promote megakaryopoiesis and synergize with alterations in GATA-1 to immortalize hematopoietic progenitor cells
- (2009) M. J. Stankiewicz et al. BLOOD
- Whole Chromosome Instability Caused by Bub1 Insufficiency Drives Tumorigenesis through Tumor Suppressor Gene Loss of Heterozygosity
- (2009) Darren J. Baker et al. CANCER CELL
- Constitutional aneuploidy and cancer predisposition
- (2009) I. Ganmore et al. HUMAN MOLECULAR GENETICS
- Chromosome 21-derived MicroRNAs Provide an Etiological Basis for Aberrant Protein Expression in Human Down Syndrome Brains
- (2009) Donald E. Kuhn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Loss of spindle assembly checkpoint–mediated inhibition of Cdc20 promotes tumorigenesis in mice
- (2009) Min Li et al. JOURNAL OF CELL BIOLOGY
- Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1
- (2009) Kwan-Hyuck Baek et al. NATURE
- A mechanism linking extra centrosomes to chromosomal instability
- (2009) Neil J. Ganem et al. NATURE
- The cancer genome
- (2009) Michael R. Stratton et al. NATURE
- Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis
- (2009) Andrew J. Holland et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Multipolar Spindle Pole Coalescence Is a Major Source of Kinetochore Mis-Attachment and Chromosome Mis-Segregation in Cancer Cells
- (2009) William T. Silkworth et al. PLoS One
- Chromosomal instability determines taxane response
- (2009) C. Swanton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Clinical and genetic heterogeneity in patients with mosaic variegated aneuploidy: Delineation of clinical subtypes
- (2008) Herbert García‐Castillo et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Aneuploidy Underlies Rapid Adaptive Evolution of Yeast Cells Deprived of a Conserved Cytokinesis Motor
- (2008) Giulia Rancati et al. CELL
- Spindle assembly checkpoint and p53 deficiencies cooperate for tumorigenesis in mice
- (2008) Ya-Hui Chi et al. INTERNATIONAL JOURNAL OF CANCER
- Examining the link between chromosomal instability and aneuploidy in human cells
- (2008) Sarah L. Thompson et al. JOURNAL OF CELL BIOLOGY
- Cancer incidence in women with Turner syndrome in Great Britain: a national cohort study
- (2008) Minouk J Schoemaker et al. LANCET ONCOLOGY
- An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1
- (2008) Anna Selmecki et al. MOLECULAR MICROBIOLOGY
- Trisomy represses Apc Min -mediated tumours in mouse models of Down’s syndrome
- (2008) Thomas E. Sussan et al. NATURE
- Genomic stability and tumour suppression by the APC/C cofactor Cdh1
- (2008) Irene García-Higuera et al. NATURE CELL BIOLOGY
- Aneuploidy Affects Proliferation and Spontaneous Immortalization in Mammalian Cells
- (2008) B. R. Williams et al. SCIENCE
- Defining ‘chromosomal instability’
- (2008) Jochen B. Geigl et al. TRENDS IN GENETICS
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