Pharmacological Inhibition of Caspase-1 Ameliorates Cisplatin-Induced Nephrotoxicity through Suppression of Apoptosis, Oxidative Stress, and Inflammation in Mice

Caspases in metabolic disease and their therapeutic potential

(2018) Claire H Wilson et al.   CELL DEATH AND DIFFERENTIATION

Venlafaxine mitigates cisplatin-induced nephrotoxicity via down-regulating apoptotic pathway in rats

(2018) Dalia H. El-Kashef et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Caspase-1 Is an Apical Caspase Leading to Caspase-3 Cleavage in the AIM2 Inflammasome Response, Independent of Caspase-8

(2018) Vitaliya Sagulenko et al.   JOURNAL OF MOLECULAR BIOLOGY

Pyruvate dehydrogenase kinase 4 deficiency attenuates cisplatin-induced acute kidney injury

(2017) Chang Joo Oh et al.   KIDNEY INTERNATIONAL

The pattern recognition receptor, Mincle, is essential for maintaining the M1 macrophage phenotype in acute renal inflammation

(2017) Lin L. Lv et al.   KIDNEY INTERNATIONAL

Protective Effects of Gemigliptin, a Dipeptidyl Peptidase-4 Inhibitor, against Cisplatin-Induced Nephrotoxicity in Mice

(2017) Seung Hee Choi et al.   MEDIATORS OF INFLAMMATION

Zinc-finger protein 418 overexpression protects against cardiac hypertrophy and fibrosis

(2017) Liming Pan et al.   PLoS One

Intranasal BMP9 Ameliorates Alzheimer Disease-Like Pathology and Cognitive Deficits in APP/PS1 Transgenic Mice

(2017) Zigao Wang et al.   Frontiers in Molecular Neuroscience

Atg5-mediated autophagy deficiency in proximal tubules promotes cell cycle G2/M arrest and renal fibrosis

(2016) Huiyan Li et al.   Autophagy

Inducible Expression of CXCL1 within the Central Nervous System Amplifies Viral-Induced Demyelination

(2016) Brett S. Marro et al.   JOURNAL OF IMMUNOLOGY

Caspase-1 inhibition alleviates acute renal injury in rats with severe acute pancreatitis

(2014) Xiao-Hua Zhang   WORLD JOURNAL OF GASTROENTEROLOGY

Caspase-1: is IL-1 just the tip of the ICEberg?

(2012) A Denes et al.   Cell Death & Disease

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

(2011) C. A. Dinarello   BLOOD

An integrative view of the pathophysiological events leading to cisplatin nephrotoxicity

(2011) Penélope D. Sánchez-González et al.   CRITICAL REVIEWS IN TOXICOLOGY

Functional Heterogeneity of CD11c-positive Adipose Tissue Macrophages in Diet-induced Obese Mice

(2010) Pingping Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol Reverses Endothelial Nitric-Oxide Synthase Uncoupling in Apolipoprotein E Knockout Mice

(2010) N. Xia et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

CD4+CD25+ regulatory T cells attenuate cisplatin-induced nephrotoxicity in mice

(2010) Hyojung Lee et al.   KIDNEY INTERNATIONAL

Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

(2010) Li Yang et al.   NATURE MEDICINE

Caspase-1 Inhibitor Prevents Neurogenic Pulmonary Edema After Subarachnoid Hemorrhage in Mice

(2009) Hidenori Suzuki et al.   STROKE

Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies

(2008) N. Pabla et al.   KIDNEY INTERNATIONAL

Interleukin-1β and interleukin-6 disturb the antioxidant enzyme system in bovine chondrocytes: a possible explanation for oxidative stress generation

(2008) M. Mathy-Hartert et al.   OSTEOARTHRITIS AND CARTILAGE