Lipocalin 2 contributes to brain iron dysregulation but does not affect cognition, plaque load, and glial activation in the J20 Alzheimer mouse model

Why should neuroscientists worry about iron? The emerging role of ferroptosis in the pathophysiology of neuroprogressive diseases

(2018) Gerwyn Morris et al.   BEHAVIOURAL BRAIN RESEARCH

Inflammatory microglia are glycolytic and iron retentive and typify the microglia in APP/PS1 mice

(2018) R. Holland et al.   BRAIN BEHAVIOR AND IMMUNITY

Inflammation-induced iron transport and metabolism by brain microglia

(2018) Ryan C. McCarthy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Astrocyte-derived lipocalin-2 mediates hippocampal damage and cognitive deficits in experimental models of vascular dementia

(2017) Jae-Hong Kim et al.   GLIA

Cortical Iron Reflects Severity of Alzheimer’s Disease

(2017) Sara van Duijn et al.   JOURNAL OF ALZHEIMERS DISEASE

Lipocalin-2 regulates adult neurogenesis and contextual discriminative behaviours

(2017) A C Ferreira et al.   MOLECULAR PSYCHIATRY

Lipocalin-2 protects the brain during inflammatory conditions

(2017) S S Kang et al.   MOLECULAR PSYCHIATRY

Astrocyte hepcidin is a key factor in LPS-induced neuronal apoptosis

(2017) Lin-Hao You et al.   Cell Death & Disease

Enhanced Histochemical Detection of Iron in Paraffin Sections of Mouse Central Nervous System Tissue

(2016) Scott A. Sands et al.   ASN Neuro

Lipocalin 2 alleviates iron toxicity by facilitating hypoferremia of inflammation and limiting catalytic iron generation

(2016) Xia Xiao et al.   BIOMETALS

Neutrophil Gelatinase-Associated Lipocalin and its Receptors in Alzheimer’s Disease (AD) Brain Regions: Differential Findings in AD with and without Depression

(2016) Doortje W. Dekens et al.   JOURNAL OF ALZHEIMERS DISEASE

Iron neurochemistry in Alzheimer's disease and Parkinson's disease: targets for therapeutics

(2016) Abdel A. Belaidi et al.   JOURNAL OF NEUROCHEMISTRY

Pathogenic Upregulation of Glial Lipocalin-2 in the Parkinsonian Dopaminergic System

(2016) B.-W. Kim et al.   JOURNAL OF NEUROSCIENCE

Role of lipocalin 2 in intraventricular haemoglobin-induced brain injury

(2016) Hajime Shishido et al.   JOURNAL OF INVESTIGATIVE MEDICINE

A Comprehensive Behavioral Test Battery to Assess Learning and Memory in 129S6/Tg2576 Mice

(2016) Andrea Wolf et al.   PLoS One

Lipocalin-2 in the Inflammatory Activation of Brain Astrocytes

(2015) Shinrye Lee et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Lipocalin-2 ensures host defense againstSalmonellaTyphimurium by controlling macrophage iron homeostasis and immune response

(2015) Manfred Nairz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Lipocalin-2 released in response to cerebral ischaemia mediates reperfusion injury in mice

(2015) Guona Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Role of Lipocalin-2 in Brain Injury after Intracerebral Hemorrhage

(2015) Wei Ni et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Neurodegeneration with inflammation is accompanied by accumulation of iron and ferritin in microglia and neurons

(2015) Maj Schneider Thomsen et al.   NEUROBIOLOGY OF DISEASE

Postoperative cognitive dysfunction and microglial activation in associated brain regions in old rats

(2015) Iris B. Hovens et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Diverse functional roles of lipocalin-2 in the central nervous system

(2015) Mithilesh Kumar Jha et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

From the periphery to the brain: Lipocalin-2, a friend or foe?

(2015) Ana C. Ferreira et al.   PROGRESS IN NEUROBIOLOGY

Intracerebral Hematoma Contributes to Hydrocephalus After Intraventricular Hemorrhage via Aggravating Iron Accumulation

(2015) Qianwei Chen et al.   STROKE

The ligands of neutrophil gelatinase-associated lipocalin

(2015) Guan-Hu Bao et al.   RSC Advances

Lipocalin 2 modulates the cellular response to amyloid beta

(2014) S D Mesquita et al.   CELL DEATH AND DIFFERENTIATION

Lipocalin-2 Protein Deficiency Ameliorates Experimental Autoimmune Encephalomyelitis

(2014) Youngpyo Nam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipocalin-2 Deficiency Attenuates Neuroinflammation and Brain Injury after Transient Middle Cerebral Artery Occlusion in Mice

(2014) Myungwon Jin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Acute White Matter Injury After Experimental Subarachnoid Hemorrhage

(2014) Yusuke Egashira et al.   STROKE

Neuronal Production of Lipocalin-2 as a Help-Me Signal for Glial Activation

(2014) Changhong Xing et al.   STROKE

Lipocalin-2 is involved in emotional behaviors and cognitive function

(2014) Ana Ferreira   Frontiers in Cellular Neuroscience

Lipocalin-2 Acts as a Neuroinflammatogen in Lipopolysaccharide-injected Mice

(2014) Myungwon Jin et al.   Experimental Neurobiology

Iron uptake in quiescent and inflammation-activated astrocytes: A potentially neuroprotective control of iron burden

(2013) Ilaria Pelizzoni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Inflammation alters the expression of DMT1, FPN1 and hepcidin, and it causes iron accumulation in central nervous system cells

(2013) Pamela Urrutia et al.   JOURNAL OF NEUROCHEMISTRY

Neutrophil gelatinase-associated lipocalin: A novel inflammatory marker associated with late-life depression

(2013) P.J.W. Naudé et al.   JOURNAL OF PSYCHOSOMATIC RESEARCH

Reactive astrocytes secrete lcn2 to promote neuron death

(2013) F. Bi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer

(2012) Subhankar Chakraborty et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Lipocalin 2: Novel component of proinflammatory signaling in Alzheimer's disease

(2012) Petrus J. W. Naudé et al.   FASEB JOURNAL

Iron homeostasis in astrocytes and microglia is differentially regulated by TNF-α and TGF-β1

(2012) Khizr I. Rathore et al.   GLIA

Lipocalin 2 is a novel immune mediator of experimental autoimmune encephalomyelitis pathogenesis and is modulated in multiple sclerosis

(2012) Jennifer L. Berard et al.   GLIA

Lipocalin 2 Deficiency Dysregulates Iron Homeostasis and Exacerbates Endotoxin-Induced Sepsis

(2012) G. Srinivasan et al.   JOURNAL OF IMMUNOLOGY

Lipocalin-2 Induces Cardiomyocyte Apoptosis by Increasing Intracellular Iron Accumulation

(2011) Guoxiong Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The contribution of activated astrocytes to Aβ production: Implications for Alzheimer's disease pathogenesis

(2011) Jie Zhao et al.   Journal of Neuroinflammation

Increased plasma levels of lipocalin 2 in mild cognitive impairment

(2011) Jihye Choi et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Lipocalin-2 controls neuronal excitability and anxiety by regulating dendritic spine formation and maturation

(2011) M. Mucha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Mammalian Siderophore Synthesized by an Enzyme with a Bacterial Homolog Involved in Enterobactin Production

(2010) Laxminarayana R. Devireddy et al.   CELL

Relationship Between Tau Pathology and Neuroinflammation in Alzheimer's Disease

(2010) Maria Jose Metcalfe et al.   MOUNT SINAI JOURNAL OF MEDICINE

Iron traffics in circulation bound to a siderocalin (Ngal)–catechol complex

(2010) Guanhu Bao et al.   Nature Chemical Biology

Astrocytes in Alzheimer’s disease

(2010) Alexei Verkhratsky et al.   Neurotherapeutics

Absence of functional Hfe protects mice from invasive Salmonella enterica Serovar Typhimurium infection via induction of lipocalin-2

(2009) M. Nairz et al.   BLOOD