Talin1 Methylation Is Required for Neutrophil Infiltration and Lipopolysaccharide-Induced Lethality

Skap2 is required for β 2 integrin–mediated neutrophil recruitment and functions

(2017) Mark Boras et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide

(2017) Laurent L. Reber et al.   JOURNAL OF EXPERIMENTAL MEDICINE

EZH2 promotes neoplastic transformation through VAV interaction-dependent extranuclear mechanisms

(2017) N Venkatesan et al.   ONCOGENE

Structural basis of kindlin-mediated integrin recognition and activation

(2017) Huadong Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphatidylinositol 4,5-Bisphosphate Modulates the Affinity of Talin-1 for Phospholipid Bilayers and Activates Its Autoinhibited Form

(2016) Xin Ye et al.   BIOCHEMISTRY

Clearance of apoptotic neutrophils and resolution of inflammation

(2016) Mallary C. Greenlee-Wacker   IMMUNOLOGICAL REVIEWS

Enhancer of Zeste Homolog 2 Inhibition Stimulates Bone Formation and Mitigates Bone Loss Caused by Ovariectomy in Skeletally Mature Mice

(2016) Amel Dudakovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kank2 activates talin, reduces force transduction across integrins and induces central adhesion formation

(2016) Zhiqi Sun et al.   NATURE CELL BIOLOGY

Structural and Functional Analysis of a Talin Triple-Domain Module Suggests an Alternative Talin Autoinhibitory Configuration

(2016) Hao Zhang et al.   STRUCTURE

Talin-KANK1 interaction controls the recruitment of cortical microtubule stabilizing complexes to focal adhesions

(2016) Benjamin P Bouchet et al.   eLife

Isolation and Activation of Murine Lymphocytes

(2016) Jun Feng Lim et al.   Jove-Journal of Visualized Experiments

Neutrophil Extracellular Traps Induce Organ Damage during Experimental and Clinical Sepsis

(2016) Paula Giselle Czaikoski et al.   PLoS One

Blocking neutrophil integrin activation prevents ischemia–reperfusion injury

(2015) Tadayuki Yago et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin

(2015) Merry Gunawan et al.   NATURE IMMUNOLOGY

Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force

(2015) Cheng-han Yu et al.   Nature Communications

Vinculin controls talin engagement with the actomyosin machinery

(2015) Paul Atherton et al.   Nature Communications

Talin1 phosphorylation activates β1 integrins: a novel mechanism to promote prostate cancer bone metastasis

(2014) J-K Jin et al.   ONCOGENE

Structural and Mechanistic Insights into the Recruitment of Talin by RIAM in Integrin Signaling

(2014) Yu-Chung Chang et al.   STRUCTURE

Talins and kindlins: partners in integrin-mediated adhesion

(2013) David A. Calderwood et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Acute Lung Injury and Acute Kidney Injury Are Established by Four Hours in Experimental Sepsis and Are Improved with Pre, but Not Post, Sepsis Administration of TNF-α Antibodies

(2013) Rhea Bhargava et al.   PLoS One

Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation

(2012) C. T. Lefort et al.   BLOOD

Arginylation-dependent regulation of a proteolytic product of talin is essential for cell–cell adhesion

(2012) Fangliang Zhang et al.   JOURNAL OF CELL BIOLOGY

Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo

(2012) Doris Proebstl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

(2012) Michael T. McCabe et al.   NATURE

Mechanisms of Leukocyte Transendothelial Migration

(2011) William A. Muller   Annual Review of Pathology-Mechanisms of Disease

Rolling Cell Adhesion

(2010) Rodger P. McEver et al.   Annual Review of Cell and Developmental Biology

E-selectin engages PSGL-1 and CD44 through a common signaling pathway to induce integrin  L 2-mediated slow leukocyte rolling

(2010) T. Yago et al.   BLOOD

Two physically, functionally, and developmentally distinct peritoneal macrophage subsets

(2010) E. E. B. Ghosn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Animal models of sepsis and sepsis-induced kidney injury

(2009) Kent Doi et al.   JOURNAL OF CLINICAL INVESTIGATION

Vav1 Is Essential for Mechanotactic Crawling and Migration of Neutrophils out of the Inflamed Microvasculature

(2009) M. Phillipson et al.   JOURNAL OF IMMUNOLOGY

Low Zone Tolerance Requires ICAM-1 Expression to Limit Contact Hypersensitivity Elicitation

(2009) Kazuhiro Komura et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Talin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration

(2009) Cai Huang et al.   NATURE CELL BIOLOGY

Structural Basis for the Autoinhibition of Talin in Regulating Integrin Activation

(2008) Esen Goksoy et al.   MOLECULAR CELL