The gut microbiome: Relationships with disease and opportunities for therapy

Propionate enters GABAergic neurons, inhibits GABA transaminase, causes GABA accumulation and lethargy in a model of propionic acidemia

(2018) Cecilie Morland et al.   BIOCHEMICAL JOURNAL

Early-Life Antibiotic-Driven Dysbiosis Leads to Dysregulated Vaccine Immune Responses in Mice

(2018) Miriam Anne Lynn et al.   Cell Host & Microbe

Fiber-Mediated Nourishment of Gut Microbiota Protects against Diet-Induced Obesity by Restoring IL-22-Mediated Colonic Health

(2018) Jun Zou et al.   Cell Host & Microbe

Bifidobacteria or Fiber Protects against Diet-Induced Microbiota-Mediated Colonic Mucus Deterioration

(2018) Bjoern O. Schroeder et al.   Cell Host & Microbe

Strain Tracking Reveals the Determinants of Bacterial Engraftment in the Human Gut Following Fecal Microbiota Transplantation

(2018) Christopher S. Smillie et al.   Cell Host & Microbe

Mother-to-Infant Microbial Transmission from Different Body Sites Shapes the Developing Infant Gut Microbiome

(2018) Pamela Ferretti et al.   Cell Host & Microbe

Selective maternal seeding and environment shape the human gut microbiome

(2018) Katri Korpela et al.   GENOME RESEARCH

Early-life home environment and risk of asthma among inner-city children

(2018) George T. O'Connor et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts

(2018) Ramón Estruch et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes

(2018) Liping Zhao et al.   SCIENCE

The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients

(2018) Vyara Matson et al.   SCIENCE

The microbiome in cancer immunotherapy: Diagnostic tools and therapeutic strategies

(2018) Laurence Zitvogel et al.   SCIENCE

Delayed gut microbiota development in high-risk for asthma infants is temporarily modifiable by Lactobacillus supplementation

(2018) Juliana Durack et al.   Nature Communications

Maturation of the gut microbiome and risk of asthma in childhood

(2018) Jakob Stokholm et al.   Nature Communications

Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development

(2018) Wei-Hung Pan et al.   Genome Medicine

Dynamics of metatranscription in the inflammatory bowel disease gut microbiome

(2018) Melanie Schirmer et al.   Nature Microbiology

Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features

(2018) Niv Zmora et al.   CELL

Precision editing of the gut microbiota ameliorates colitis

(2018) Wenhan Zhu et al.   NATURE

Environment dominates over host genetics in shaping human gut microbiota

(2018) Daphna Rothschild et al.   NATURE

Supplemental feeding of a gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, alleviates spontaneous atopic dermatitis and modulates intestinal microbiota in NC/nga mice

(2017) Hiroko Kaikiri et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Two rheumatoid arthritis–specific autoantigens correlate microbial immunity with autoimmune responses in joints

(2017) Annalisa Pianta et al.   JOURNAL OF CLINICAL INVESTIGATION

Microbial-Derived Butyrate Promotes Epithelial Barrier Function through IL-10 Receptor–Dependent Repression of Claudin-2

(2017) Leon Zheng et al.   JOURNAL OF IMMUNOLOGY

The incidence of multiple sclerosis in Danish women has duplicated over the last sixty years

(2017) M. Magyari et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Microbiome-driven allergic lung inflammation is ameliorated by short-chain fatty acids

(2017) A Cait et al.   Mucosal Immunology

β-Glucans in food modify colonic microflora by inducing antimicrobial protein, calprotectin, in a Dectin-1-induced-IL-17F-dependent manner

(2017) T Kamiya et al.   Mucosal Immunology

Lactobacillus johnsonii supplementation attenuates respiratory viral infection via metabolic reprogramming and immune cell modulation

(2017) W Fonseca et al.   Mucosal Immunology

Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring

(2017) Sangdoo Kim et al.   NATURE

High-avidity IgA protects the intestine by enchaining growing bacteria

(2017) Kathrin Moor et al.   NATURE

Maturation of the infant microbiome community structure and function across multiple body sites and in relation to mode of delivery

(2017) Derrick M Chu et al.   NATURE MEDICINE

Interactions between the microbiota, immune and nervous systems in health and disease

(2017) Thomas C Fung et al.   NATURE NEUROSCIENCE

Bifidobacterium adolescentis IM38 ameliorates high-fat diet–induced colitis in mice by inhibiting NF-κB activation and lipopolysaccharide production by gut microbiota

(2017) Su-Min Lim et al.   NUTRITION RESEARCH

Early life antibiotic use and the risk of asthma and asthma exacerbations in children

(2017) Fariba Ahmadizar et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Early Probiotic Supplementation for Eczema and Asthma Prevention: A Randomized Controlled Trial

(2017) Michael D. Cabana et al.   PEDIATRICS

Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models

(2017) Egle Cekanaviciute et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prevalence of rheumatoid arthritis in the United States adult population in healthcare claims databases, 2004–2014

(2017) Theresa M. Hunter et al.   RHEUMATOLOGY INTERNATIONAL

Lactobacillus reuteriinduces gut intraepithelial CD4+CD8αα+T cells

(2017) Luisa Cervantes-Barragan et al.   SCIENCE

Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

(2017) V. Gopalakrishnan et al.   SCIENCE

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

(2017) Bertrand Routy et al.   SCIENCE

Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis

(2017) Teruaki Nakatsuji et al.   Science Translational Medicine

The Gut Microbiota and Autism Spectrum Disorders

(2017) Qinrui Li et al.   Frontiers in Cellular Neuroscience

A single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity

(2017) Victoria E. Ruiz et al.   Nature Communications

Conjugated Linoleic Acid Supplementation Improves Maternal High Fat Diet-Induced Programming of Metabolic Dysfunction in Adult Male Rat Offspring

(2017) Stephanie A. Segovia et al.   Scientific Reports

Microbiota alteration is associated with the development of stress-induced despair behavior

(2017) Ioana A. Marin et al.   Scientific Reports

Microbial Anti-Inflammatory Molecule (MAM) from Faecalibacterium prausnitzii Shows a Protective Effect on DNBS and DSS-Induced Colitis Model in Mice through Inhibition of NF-κB Pathway

(2017) Natalia M. Breyner et al.   Frontiers in Microbiology

Butyrate Conditions Human Dendritic Cells to Prime Type 1 Regulatory T Cells via both Histone Deacetylase Inhibition and G Protein-Coupled Receptor 109A Signaling

(2017) Maria M. M. Kaisar et al.   Frontiers in Immunology

The Impact of Gut Microbiota on Gender-Specific Differences in Immunity

(2017) Floris Fransen et al.   Frontiers in Immunology

New evidences on the altered gut microbiota in autism spectrum disorders

(2017) Francesco Strati et al.   Microbiome

Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study

(2017) Dae-Wook Kang et al.   Microbiome

Pili-like proteins of Akkermansia muciniphila modulate host immune responses and gut barrier function

(2017) Noora Ottman et al.   PLoS One

Gut microbiota composition is associated with polypharmacy in elderly hospitalized patients

(2017) Andrea Ticinesi et al.   Scientific Reports

Age-related changes in gut microbiota composition from newborn to centenarian: a cross-sectional study

(2016) Toshitaka Odamaki et al.   BMC MICROBIOLOGY

Associations between the gut microbiota and host immune markers in pediatric multiple sclerosis and controls

(2016) Helen Tremlett et al.   BMC Neurology

An orally administered butyrate-releasing derivative reduces neutrophil recruitment and inflammation in dextran sulphate sodium-induced murine colitis

(2016) Raffaele Simeoli et al.   BRITISH JOURNAL OF PHARMACOLOGY

Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans

(2016) Tommi Vatanen et al.   CELL

Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans

(2016) Ron Sender et al.   CELL

Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity

(2016) Melanie Schirmer et al.   CELL

Microbial Reconstitution Reverses Maternal Diet-Induced Social and Synaptic Deficits in Offspring

(2016) Shelly A. Buffington et al.   CELL

A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

(2016) Mahesh S. Desai et al.   CELL

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

(2016) Weifei Zhu et al.   CELL

Immunological Consequences of Intestinal Fungal Dysbiosis

(2016) Matthew L. Wheeler et al.   Cell Host & Microbe

Effects of Gut Microbiota Manipulation by Antibiotics on Host Metabolism in Obese Humans: A Randomized Double-Blind Placebo-Controlled Trial

(2016) Dorien Reijnders et al.   Cell Metabolism

The Intestinal Immune System in Obesity and Insulin Resistance

(2016) Daniel A. Winer et al.   Cell Metabolism

Sodium butyrate reduces insulin-resistance, fat accumulation and dyslipidemia in type-2 diabetic rat: A comparative study with metformin

(2016) Sabbir Khan et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Akkermansia MuciniphilaProtects Against Atherosclerosis by Preventing Metabolic Endotoxemia-Induced Inflammation inApoe−/−MiceCLINICAL PERSPECTIVE

(2016) Jin Li et al.   CIRCULATION

Airway Microbiota and the Implications of Dysbiosis in Asthma

(2016) Juliana Durack et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Gut Microbiota and Extreme Longevity

(2016) Elena Biagi et al.   CURRENT BIOLOGY

Probiotics for the management of type 2 diabetes mellitus: A systematic review and meta-analysis

(2016) Syamimi Samah et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Beneficial metabolic effects of selected probiotics on diet-induced obesity and insulin resistance in mice are associated with improvement of dysbiotic gut microbiota

(2016) Jeanne Alard et al.   ENVIRONMENTAL MICROBIOLOGY

Gut microbiota in early pediatric multiple sclerosis: a case−control study

(2016) H. Tremlett et al.   EUROPEAN JOURNAL OF NEUROLOGY

Modulation of inflammation and immunity by dietary conjugated linoleic acid

(2016) Monica Viladomiu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Fungal microbiota dysbiosis in IBD

(2016) Harry Sokol et al.   GUT

Ecological robustness of the gut microbiota in response to ingestion of transient food-borne microbes

(2016) Chenhong Zhang et al.   ISME Journal

Cesarean section changes neonatal gut colonization

(2016) Jakob Stokholm et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Comparison of the gut microbial community between obese and lean peoples using 16S gene sequencing in a Japanese population

(2016) Akira Andoh et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Genetic, Immune-Inflammatory, and Oxidative Stress Biomarkers as Predictors for Disability and Disease Progression in Multiple Sclerosis

(2016) Ana Paula Kallaur et al.   MOLECULAR NEUROBIOLOGY

Pretreatment with antibiotics may enhance the efficacy of fecal microbiota transplantation in ulcerative colitis: a meta-analysis

(2016) A H Keshteli et al.   Mucosal Immunology

Development of the gut microbiota and mucosal IgA responses in twins and gnotobiotic mice

(2016) Joseph D. Planer et al.   NATURE

Human gut microbes impact host serum metabolome and insulin sensitivity

(2016) Helle Krogh Pedersen et al.   NATURE

Diet-induced extinctions in the gut microbiota compound over generations

(2016) Erica D. Sonnenburg et al.   NATURE

The effect of host genetics on the gut microbiome

(2016) Marc Jan Bonder et al.   NATURE GENETICS

Association of host genome with intestinal microbial composition in a large healthy cohort

(2016) Williams Turpin et al.   NATURE GENETICS

Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer

(2016) Maria G Dominguez-Bello et al.   NATURE MEDICINE

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

(2016) Bruno Lamas et al.   NATURE MEDICINE

Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation

(2016) Kei E Fujimura et al.   NATURE MEDICINE

A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

(2016) Hubert Plovier et al.   NATURE MEDICINE

Quorum sensing signal–response systems in Gram-negative bacteria

(2016) Kai Papenfort et al.   NATURE REVIEWS MICROBIOLOGY

Lactobacillus sakei OK67 ameliorates high-fat diet–induced blood glucose intolerance and obesity in mice by inhibiting gut microbiota lipopolysaccharide production and inducing colon tight junction protein expression

(2016) Su-Min Lim et al.   NUTRITION RESEARCH

New inducible genetic method reveals critical roles of GABA in the control of feeding and metabolism

(2016) Fantao Meng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut microbiota induce IGF-1 and promote bone formation and growth

(2016) Jing Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cosmcis an X-linked inflammatory bowel disease risk gene that spatially regulates gut microbiota and contributes to sex-specific risk

(2016) Matthew R. Kudelka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice

(2016) Tze Guan Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Durable coexistence of donor and recipient strains after fecal microbiota transplantation

(2016) Simone S. Li et al.   SCIENCE

A secreted bacterial peptidoglycan hydrolase enhances tolerance to enteric pathogens

(2016) K. J. Rangan et al.   SCIENCE

Helminth infection promotes colonization resistance via type 2 immunity

(2016) Deepshika Ramanan et al.   SCIENCE

How colonization by microbiota in early life shapes the immune system

(2016) Thomas Gensollen et al.   SCIENCE

Lactobacillus plantarum strain maintains growth of infant mice during chronic undernutrition

(2016) M. Schwarzer et al.   SCIENCE

Antibiotics, birth mode, and diet shape microbiome maturation during early life

(2016) Nicholas A. Bokulich et al.   Science Translational Medicine

Disease Severity and Immune Activity Relate to Distinct Interkingdom Gut Microbiome States in Ethnically Distinct Ulcerative Colitis Patients

(2016) Jordan S. Mar et al.   mBio

Intestinal microbiome is related to lifetime antibiotic use in Finnish pre-school children

(2016) Katri Korpela et al.   Nature Communications

The healthy human microbiome

(2016) Jason Lloyd-Price et al.   Genome Medicine

Signatures of early frailty in the gut microbiota

(2016) Matthew A. Jackson et al.   Genome Medicine

Sensitive Quantitative Analysis of the Meconium Bacterial Microbiota in Healthy Term Infants Born Vaginally or by Cesarean Section

(2016) Ravinder Nagpal et al.   Frontiers in Microbiology

Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study

(2016) Ulla Uusitalo et al.   JAMA Pediatrics

Propionate Ameliorates Dextran Sodium Sulfate-Induced Colitis by Improving Intestinal Barrier Function and Reducing Inflammation and Oxidative Stress

(2016) Ling-chang Tong et al.   Frontiers in Pharmacology

Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome

(2016) Hailiang Xie et al.   Cell Systems

Influence of early life exposure, host genetics and diet on the mouse gut microbiome and metabolome

(2016) Antoine M. Snijders et al.   Nature Microbiology

Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice

(2016) Alexandra E. Livanos et al.   Nature Microbiology

Faecalibacterium prausnitzii A2-165 has a high capacity to induce IL-10 in human and murine dendritic cells and modulates T cell responses

(2016) Oriana Rossi et al.   Scientific Reports

Human gut colonisation may be initiated in utero by distinct microbial communities in the placenta and amniotic fluid

(2016) Maria Carmen Collado et al.   Scientific Reports

Joint effects of pregnancy, sociocultural, and environmental factors on early life gut microbiome structure and diversity

(2016) Albert M. Levin et al.   Scientific Reports

Impact of the microbial derived short chain fatty acid propionate on host susceptibility to bacterial and fungal infections in vivo

(2016) Eleonora Ciarlo et al.   Scientific Reports

Maternal hospitalization with infection during pregnancy and risk of autism spectrum disorders

(2015) Brian K. Lee et al.   BRAIN BEHAVIOR AND IMMUNITY

Dietary modulation of the gut microbiota – a randomised controlled trial in obese postmenopausal women

(2015) Lena K. Brahe et al.   BRITISH JOURNAL OF NUTRITION

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

(2015) Jessica M. Yano et al.   CELL

Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling

(2015) Maayan Levy et al.   CELL

Personalized Nutrition by Prediction of Glycemic Responses

(2015) David Zeevi et al.   CELL

Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis

(2015) Zeneng Wang et al.   CELL

Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences

(2015) Petter Brodin et al.   CELL

Microbiota in Allergy and Asthma and the Emerging Relationship with the Gut Microbiome

(2015) Kei E. Fujimura et al.   Cell Host & Microbe

Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life

(2015) Fredrik Bäckhed et al.   Cell Host & Microbe

Inhibition of Dectin-1 Signaling Ameliorates Colitis by Inducing Lactobacillus-Mediated Regulatory T Cell Expansion in the Intestine

(2015) Ce Tang et al.   Cell Host & Microbe

The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes

(2015) Aleksandar D. Kostic et al.   Cell Host & Microbe

Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function

(2015) Caleb J. Kelly et al.   Cell Host & Microbe

The Probiotic VSL#3 Has Anti-inflammatory Effects and Could Reduce Endoscopic Recurrence After Surgery for Crohn's Disease

(2015) Richard N. Fedorak et al.   Clinical Gastroenterology and Hepatology

Short-Chain Fatty Acids Protect Against High-Fat Diet–Induced Obesity via a PPARγ-Dependent Switch From Lipogenesis to Fat Oxidation

(2015) Gijs den Besten et al.   DIABETES

Chronic cigarette smoke exposure induces microbial and inflammatory shifts and mucin changes in the murine gut

(2015) Liesbeth Allais et al.   ENVIRONMENTAL MICROBIOLOGY

Proton pump inhibitors affect the gut microbiome

(2015) Floris Imhann et al.   GUT

Akkermansia muciniphilaand improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology

(2015) Maria Carlota Dao et al.   GUT

Identification of an anti-inflammatory protein fromFaecalibacterium prausnitzii, a commensal bacterium deficient in Crohn’s disease

(2015) E Quévrain et al.   GUT

A Wave of Regulatory T Cells into Neonatal Skin Mediates Tolerance to Commensal Microbes

(2015) Tiffany C. Scharschmidt et al.   IMMUNITY

Discordant temporal development of bacterial phyla and the emergence of core in the fecal microbiota of young children

(2015) Jing Cheng et al.   ISME Journal

Commensal–dendritic-cell interaction specifies a unique protective skin immune signature

(2015) Shruti Naik et al.   NATURE

Growth and host interaction of mouse segmented filamentous bacteria in vitro

(2015) Pamela Schnupf et al.   NATURE

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

(2015) Kristoffer Forslund et al.   NATURE

Activation of HIF-1α and LL-37 by commensal bacteria inhibits Candida albicans colonization

(2015) Di Fan et al.   NATURE MEDICINE

The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment

(2015) Xuan Zhang et al.   NATURE MEDICINE

Early life dynamics of the human gut virome and bacterial microbiome in infants

(2015) Efrem S Lim et al.   NATURE MEDICINE

Gut biogeography of the bacterial microbiota

(2015) Gregory P. Donaldson et al.   NATURE REVIEWS MICROBIOLOGY

Identifying personal microbiomes using metagenomic codes

(2015) Eric A. Franzosa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolution of the immune system in humans from infancy to old age

(2015) A. Katharina Simon et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Small molecules from the human microbiota

(2015) M. S. Donia et al.   SCIENCE

The microbiota regulates type 2 immunity through ROR t+ T cells

(2015) C. Ohnmacht et al.   SCIENCE

Individual intestinal symbionts induce a distinct population of ROR + regulatory T cells

(2015) E. Sefik et al.   SCIENCE

Early infancy microbial and metabolic alterations affect risk of childhood asthma

(2015) Marie-Claire Arrieta et al.   Science Translational Medicine

Structure and function of the healthy pre-adolescent pediatric gut microbiome

(2015) Emily B. Hollister et al.   Microbiome

Systematic genome assessment of B-vitamin biosynthesis suggests co-operation among gut microbes

(2015) Stefanía Magnúsdóttir et al.   Frontiers in Genetics

Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice

(2015) Marc Schneeberger et al.   Scientific Reports

Randomised clinical trial: the beneficial effects of VSL#3 in obese children with non-alcoholic steatohepatitis

(2014) A. Alisi et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Human Genetics Shape the Gut Microbiome

(2014) Julia K. Goodrich et al.   CELL

Sphingolipids from a Symbiotic Microbe Regulate Homeostasis of Host Intestinal Natural Killer T Cells

(2014) Dingding An et al.   CELL

Gut Microbiota Promote Hematopoiesis to Control Bacterial Infection

(2014) Arya Khosravi et al.   Cell Host & Microbe

Plasmacytoid Dendritic Cells Mediate Anti-inflammatory Responses to a Gut Commensal Molecule via Both Innate and Adaptive Mechanisms

(2014) Suryasarathi Dasgupta et al.   Cell Host & Microbe

The Treatment-Naive Microbiome in New-Onset Crohn’s Disease

(2014) Dirk Gevers et al.   Cell Host & Microbe

Arsenic Exposure Perturbs the Gut Microbiome and Its Metabolic Profile in Mice: An Integrated Metagenomics and Metabolomics Analysis

(2014) Kun Lu et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increasedAkkermansiaspp. population in the gut microbiota of mice

(2014) Fernando F Anhê et al.   GUT

Comparative metabolomics in vegans and omnivores reveal constraints on diet-dependent gut microbiota metabolite production

(2014) Gary D Wu et al.   GUT

Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4

(2014) Madhukumar Venkatesh et al.   IMMUNITY

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

(2014) Nagendra Singh et al.   IMMUNITY

A Gut Microbial Metabolite of Linoleic Acid, 10-Hydroxy-cis-12-octadecenoic Acid, Ameliorates Intestinal Epithelial Barrier Impairment Partially via GPR40-MEK-ERK Pathway

(2014) Junki Miyamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fecal microbiota transplantation as therapy for inflammatory bowel disease: A systematic review and meta-analysis

(2014) Ruben J. Colman et al.   Journal of Crohns & Colitis

Regulatory T cells promote a protective Th17-associated immune response to intestinal bacterial infection with C. rodentium

(2014) Z Wang et al.   Mucosal Immunology

Biogeography and individuality shape function in the human skin metagenome

(2014) Julia Oh et al.   NATURE

Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile

(2014) Charlie G. Buffie et al.   NATURE

Persistent gut microbiota immaturity in malnourished Bangladeshi children

(2014) Sathish Subramanian et al.   NATURE

An integrated catalog of reference genes in the human gut microbiome

(2014) Junhua Li et al.   NATURE BIOTECHNOLOGY

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

(2014) Aurélien Trompette et al.   NATURE MEDICINE

The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition

(2014) Pamela V. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Placenta Harbors a Unique Microbiome

(2014) K. Aagaard et al.   Science Translational Medicine

Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection

(2014) Casey M. Theriot et al.   Nature Communications

Bacterial Metabolite Indole Modulates Incretin Secretion from Intestinal Enteroendocrine L Cells

(2014) Catalin Chimerel et al.   Cell Reports

The dynamics of a family’s gut microbiota reveal variations on a theme

(2014) Patrick D Schloss et al.   Microbiome

Differential Induction of Antimicrobial REGIII by the Intestinal Microbiota and Bifidobacterium breve NCC2950

(2013) Jane M. M. Natividad et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

(2013) Elaine Y. Hsiao et al.   CELL

Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome

(2013) Corinne Ferrier Maurice et al.   CELL

Decreased gut microbiota diversity, delayed Bacteroidetes colonisation and reduced Th1 responses in infants delivered by Caesarean section

(2013) Hedvig E Jakobsson et al.   GUT

An increase in theAkkermansiaspp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice

(2013) Na-Ri Shin et al.   GUT

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

(2013) Teresa Zelante et al.   IMMUNITY

IL-22 Deficiency Alters Colonic Microbiota To Be Transmissible and Colitogenic

(2013) L. A. Zenewicz et al.   JOURNAL OF IMMUNOLOGY

Elevated maternal C-reactive protein and autism in a national birth cohort

(2013) A S Brown et al.   MOLECULAR PSYCHIATRY

Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria

(2013) Matthew R. Hepworth et al.   NATURE

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Dietary intervention impact on gut microbial gene richness

(2013) Aurélie Cotillard et al.   NATURE

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota

(2013) Koji Atarashi et al.   NATURE

Gut metagenome in European women with normal, impaired and diabetic glucose control

(2013) Fredrik H. Karlsson et al.   NATURE

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile

(2013) Els van Nood et al.   NEW ENGLAND JOURNAL OF MEDICINE

Probiotic Administration in Early Life, Atopy, and Asthma: A Meta-analysis of Clinical Trials

(2013) N. Elazab et al.   PEDIATRICS

Microbial Symbionts Accelerate Wound Healing via the Neuropeptide Hormone Oxytocin

(2013) Theofilos Poutahidis et al.   PLoS One

House dust exposure mediates gut microbiome Lactobacillus enrichment and airway immune defense against allergens and virus infection

(2013) K. E. Fujimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

The Long-Term Stability of the Human Gut Microbiota

(2013) J. J. Faith et al.   SCIENCE

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

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Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

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Gut Immune Maturation Depends on Colonization with a Host-Specific Microbiota

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Meconium microbiota types dominated by lactic acid or enteric bacteria are differentially associated with maternal eczema and respiratory problems in infants

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Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome

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Gut microbiota composition correlates with diet and health in the elderly

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A metagenome-wide association study of gut microbiota in type 2 diabetes

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CD4+CD25+Foxp3+ Regulatory T Cells Promote Th17 Cells In Vitro and Enhance Host Resistance in Mouse Candida albicans Th17 Cell Infection Model

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Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

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The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication

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Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells

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Reversible Microbial Colonization of Germ-Free Mice Reveals the Dynamics of IgA Immune Responses

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IL-22+ CD4+ T Cells Are Associated with Therapeutic Trichuris trichiura Infection in an Ulcerative Colitis Patient

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Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

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The Probiotic Preparation, VSL#3 Induces Remission in Patients With Mild-to-Moderately Active Ulcerative Colitis

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Indole-3-propionic acid attenuates neuronal damage and oxidative stress in the ischemic hippocampus

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Dietary Patterns and the Risk of Acute Myocardial Infarction in 52 Countries

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A new class of homoserine lactone quorum-sensing signals

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A core gut microbiome in obese and lean twins

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Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

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