The role of PGC-1 coactivators in aging skeletal muscle and heart

PGC-1β regulates angiogenesis in skeletal muscle

(2011) Glenn C. Rowe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The PGC-1α-related coactivator promotes mitochondrial and myogenic adaptations in C2C12 myotubes

(2011) Andrew Philp et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Mitochondrial biogenesis and PGC-1α deacetylation by chronic treadmill exercise: differential response in cardiac and skeletal muscle

(2011) Ling Li et al.   BASIC RESEARCH IN CARDIOLOGY

The Unfolded Protein Response Mediates Adaptation to Exercise in Skeletal Muscle through a PGC-1α/ATF6α Complex

(2011) Jun Wu et al.   Cell Metabolism

Exercise and PGC-1α-Independent Synchronization of Type I Muscle Metabolism and Vasculature by ERRγ

(2011) Vihang A. Narkar et al.   Cell Metabolism

In Vivo Correction of COX Deficiency by Activation of the AMPK/PGC-1α Axis

(2011) Carlo Viscomi et al.   Cell Metabolism

Effect of bezafibrate treatment on late-onset mitochondrial myopathy in mice

(2011) Shuichi Yatsuga et al.   HUMAN MOLECULAR GENETICS

Exercise Increases Mitochondrial PGC-1α Content and Promotes Nuclear-Mitochondrial Cross-talk to Coordinate Mitochondrial Biogenesis

(2011) Adeel Safdar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial DNA transcription regulation and nucleoid organization

(2011) Adriana P. Rebelo et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Increases in mitochondrial biogenesis impair carcinogenesis at multiple levels

(2011) Xiao Wang et al.   Molecular Oncology

Ageing theories unified

(2011) Daniel P. Kelly   NATURE

Telomere dysfunction induces metabolic and mitochondrial compromise

(2011) Ergün Sahin et al.   NATURE

ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1

(2011) Guenter Haemmerle et al.   NATURE MEDICINE

Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice

(2011) A. Safdar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exercise Therapy in Hypertensive Cardiovascular Disease

(2011) Robert H. Fagard   PROGRESS IN CARDIOVASCULAR DISEASES

Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria

(2010) Dao-Fu Dai et al.   AGING CELL

Total Skeletal Muscle PGC-1 Deficiency Uncouples Mitochondrial Derangements from Fiber Type Determination and Insulin Sensitivity

(2010) Christoph Zechner et al.   Cell Metabolism

PGC-1 Coactivators in Cardiac Development and Disease

(2010) Glenn C. Rowe et al.   CIRCULATION RESEARCH

Estrogen-related receptor α and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria

(2010) Delphine Mirebeau-Prunier et al.   FEBS Journal

Peroxisome Proliferator-activated Receptor γ Coactivator 1α or 1β Overexpression Inhibits Muscle Protein Degradation, Induction of Ubiquitin Ligases, and Disuse Atrophy

(2010) Jeffrey J. Brault et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxisome Proliferator-activated Receptor γ Co-activator 1α (PGC-1α) and Sirtuin 1 (SIRT1) Reside in Mitochondria

(2010) Katia Aquilano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease

(2010) Jun Ren et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Aberrant Mitochondrial Homeostasis in the Skeletal Muscle of Sedentary Older Adults

(2010) Adeel Safdar et al.   PLoS One

Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice

(2010) Asimina Hiona et al.   PLoS One

PGC-1  regulates a HIF2 -dependent switch in skeletal muscle fiber types

(2010) K. A. Rasbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial biogenesis in exercise and in ageing☆

(2009) Jose Viña et al.   ADVANCED DRUG DELIVERY REVIEWS

The role of PGC-1α on mitochondrial function and apoptotic susceptibility in muscle

(2009) Peter J. Adhihetty et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

PGC-1α in aging and anti-aging interventions

(2009) Rozalyn Anderson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

PGC-1α/β induced expression partially compensates for respiratory chain defects in cells from patients with mitochondrial disorders

(2009) Sarika Srivastava et al.   HUMAN MOLECULAR GENETICS

Endurance exercise is protective for mice with mitochondrial myopathy

(2009) Tina Wenz et al.   JOURNAL OF APPLIED PHYSIOLOGY

PGC-1α and PGC-1β Regulate Mitochondrial Density in Neurons

(2009) Przemyslaw Wareski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

Increased muscle PGC-1  expression protects from sarcopenia and metabolic disease during aging

(2009) T. Wenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The transcriptional coactivator PGC-1α mediates exercise-induced angiogenesis in skeletal muscle

(2009) Jessica Chinsomboon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The biology of PGC-1α and its therapeutic potential

(2009) Christoph Handschin   TRENDS IN PHARMACOLOGICAL SCIENCES

The transcriptional coactivator PGC-1α is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis

(2008) John J. Lehman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Suppression of the aging-associated decline in physical performance by a combination of resveratrol intake and habitual exercise in senescence-accelerated mice

(2008) Takatoshi Murase et al.   BIOGERONTOLOGY

Cellular and molecular mechanisms underlying age-related skeletal muscle wasting and weakness

(2008) James G. Ryall et al.   BIOGERONTOLOGY

RETRACTED: Activation of the PPAR/PGC-1α Pathway Prevents a Bioenergetic Deficit and Effectively Improves a Mitochondrial Myopathy Phenotype

(2008) Tina Wenz et al.   Cell Metabolism

Skeletal muscle proteolysis in aging

(2008) Lydie Combaret et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

PGC-1 coactivators and skeletal muscle adaptations in health and disease

(2008) Zolt Arany   CURRENT OPINION IN GENETICS & DEVELOPMENT

Transcriptional coactivators PGC-1  and PGC-l  control overlapping programs required for perinatal maturation of the heart

(2008) L. Lai et al.   GENES & DEVELOPMENT

Activation of Peroxisome Proliferator-Activated Receptor Pathway Stimulates the Mitochondrial Respiratory Chain and Can Correct Deficiencies in Patients’ Cells Lacking Its Components

(2008) Jean Bastin et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The PPAR trio: Regulators of myocardial energy metabolism in health and disease

(2008) Jose A. Madrazo et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

PGC-1α and ERRα target gene downregulation is a signature of the failing human heart

(2008) Smita Sihag et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

(2008) Zoltan Arany et al.   NATURE

Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function

(2008) Richard C. Scarpulla   PHYSIOLOGICAL REVIEWS