Adiponectin Attenuates Angiotensin II-Induced Vascular Smooth Muscle Cell Remodeling through Nitric Oxide and the RhoA/ROCK Pathway

Angiotensin II Activates the RhoA Exchange Factor Arhgef1 in HumansNovelty and Significance

(2015) Maria Luigia Carbone et al.   HYPERTENSION

A novel cardioprotective mechanism of exogenous nitric oxide: inhibition of Rho-associated kinase activity

(2015) Atsushi Tanaka et al.   HYPERTENSION RESEARCH

Differential Role of Leptin and Adiponectin in Cardiovascular System

(2015) C. M. Ghantous et al.   International Journal of Endocrinology

Mechanical stretch-induced vascular hypertrophy occurs through modulation of leptin synthesis-mediated ROS formation and GATA-4 nuclear translocation

(2015) Crystal M. Ghantous et al.   Frontiers in Pharmacology

Back to the heart: The protective role of adiponectin

(2014) C. Caselli et al.   PHARMACOLOGICAL RESEARCH

Critical Role of Exogenous Nitric Oxide in ROCK Activity in Vascular Smooth Muscle Cells

(2014) Tatsuya Maruhashi et al.   PLoS One

Adiponectin Receptor as a Key Player in Healthy Longevity and Obesity-Related Diseases

(2013) Toshimasa Yamauchi et al.   Cell Metabolism

Adiponectin Levels and the Risk of Hypertension

(2013) Dae Hyun Kim et al.   HYPERTENSION

Prevention of RhoA activation and cofilin-mediated actin polymerization mediates the antihypertrophic effect of adenosine receptor agonists in angiotensin II- and endothelin-1-treated cardiomyocytes

(2013) Asad Zeidan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Angiotensin II Reduces Cardiac AdipoR1 Expression through AT1 Receptor/ROS/ERK1/2/c-Myc Pathway

(2013) Li Li et al.   PLoS One

Molecular Mechanisms of Hypertension—Reactive Oxygen Species and Antioxidants: A Basic Science Update for the Clinician

(2012) Augusto C. Montezano et al.   CANADIAN JOURNAL OF CARDIOLOGY

Nitric oxide enhances the anti-inflammatory and anti-atherogenic activity of atorvastatin in a mouse model of accelerated atherosclerosis

(2012) Stefania Momi et al.   CARDIOVASCULAR RESEARCH

Adiponectin Single Nucleotide Polymorphism is a Genetic Risk Factor for Stroke Through High Pulse Wave Pressure: A Cohort Study

(2012) Tatsuo Kawai et al.   Journal of Atherosclerosis and Thrombosis

Hypertension and acute myocardial infarction

(2012) Roberto Pedrinelli et al.   Journal of Cardiovascular Medicine

Adiponectin inhibits the generation of reactive oxygen species induced by high glucose and promotes endothelial NO synthase formation in human mesangial cells

(2012) FANG YUAN et al.   Molecular Medicine Reports

Increased availability of angiotensin AT1receptors leads to sustained arterial constriction to angiotensin II in diabetes - role for Rho-kinase activation

(2011) Zsolt Bagi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mitochondrial Oxidative Stress Mediates Angiotensin II–Induced Cardiac Hypertrophy and Gαq Overexpression–Induced Heart Failure

(2011) Dao-Fu Dai et al.   CIRCULATION RESEARCH

SIRT1 inhibits angiotensin II-induced vascular smooth muscle cell hypertrophy

(2010) L. Li et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Adiponectin and Hypertension

(2010) K. Ohashi et al.   AMERICAN JOURNAL OF HYPERTENSION

Involvement of mTOR in globular adiponectin-induced generation of reactive oxygen species

(2010) Akie Fujimoto et al.   FREE RADICAL RESEARCH

Reactive oxygen species and vascular biology: implications in human hypertension

(2010) Rhian M Touyz et al.   HYPERTENSION RESEARCH

Plasma Adiponectin Levels and Left Ventricular Remodeling in Hypertrophic Cardiomyopathy

(2010) Hiroaki Kitaoka et al.   International Heart Journal

Vasodilator efficacy of nitric oxide depends on mechanisms of intracellular calcium mobilization in mouse aortic smooth muscle cells

(2009) CE Van Hove et al.   BRITISH JOURNAL OF PHARMACOLOGY

Globular adiponectin inhibits angiotensin II-induced nuclear factor κB activation through AMP-activated protein kinase in cardiac hypertrophy

(2009) Cheng Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Nitric oxide inhibits endothelin-1-induced neonatal cardiomyocyte hypertrophy via a RhoA-ROCK-dependent pathway

(2009) J. Craig Hunter et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies

(2009) Shoba Shetty et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Myosin light chain kinase activation and calcium sensitization in smooth muscle in vivo

(2008) Yusuke Mizuno et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Adiponectin Protects Against Angiotensin II–Induced Cardiac Fibrosis Through Activation of PPAR-α

(2008) Koichi Fujita et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vascular effects of adiponectin: molecular mechanisms and potential therapeutic intervention

(2008) Weidong Zhu et al.   CLINICAL SCIENCE

Effects of losartan on serum total and high–molecular weight adiponectin concentrations in hypertensive patients with metabolic syndrome

(2008) Toshihiko Uchida et al.   METABOLISM-CLINICAL AND EXPERIMENTAL