Characterization of Host Responses during Pseudomonas aeruginosa Acute Infection in the Lungs and Blood and after Treatment with the Synthetic Immunomodulatory Peptide IDR-1002

Computer-aided Discovery of Peptides that Specifically Attack Bacterial Biofilms

(2018) Evan F. Haney et al.   Scientific Reports

Synergy between conventional antibiotics and anti-biofilm peptides in a murine, sub-cutaneous abscess model caused by recalcitrant ESKAPE pathogens

(2018) Daniel Pletzer et al.   PLoS Pathogens

Mechanisms of the Innate Defense Regulator Peptide-1002 Anti-Inflammatory Activity in a Sterile Inflammation Mouse Model

(2017) Bing Catherine Wu et al.   JOURNAL OF IMMUNOLOGY

Synthetic host defense peptide IDR-1002 reduces inflammation in Pseudomonas aeruginosa lung infection

(2017) Kelli C. Wuerth et al.   PLoS One

In vitro and in vivo evaluation of BMAP-derived peptides for the treatment of cystic fibrosis-related pulmonary infections

(2016) Mario Mardirossian et al.   AMINO ACIDS

Clinical Practice Guidelines for Hospital-Acquired Pneumonia and Ventilator-Associated Pneumonia in Adults

(2016) Coleman Rotstein et al.   Canadian Journal of Infectious Diseases & Medical Microbiology

Dual-seq transcriptomics reveals the battle for iron during Pseudomonas aeruginosa acute murine pneumonia

(2016) F. Heath Damron et al.   Scientific Reports

Anti-infective peptide IDR-1002 augments monocyte chemotaxis towards CCR5 chemokines

(2015) Laurence Madera et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Orchestrating high-throughput genomic analysis with Bioconductor

(2015) Wolfgang Huber et al.   NATURE METHODS

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Peptide IDR-1018: modulating the immune system and targeting bacterial biofilms to treat antibiotic-resistant bacterial infections

(2014) Sarah C. Mansour et al.   JOURNAL OF PEPTIDE SCIENCE

NetworkAnalyst - integrative approaches for protein–protein interaction network analysis and visual exploration

(2014) Jianguo Xia et al.   NUCLEIC ACIDS RESEARCH

Depletion of Cutaneous Macrophages and Dendritic Cells Promotes Growth of Basal Cell Carcinoma in Mice

(2014) Simone König et al.   PLoS One

Ten years of next-generation sequencing technology

(2014) Erwin L. van Dijk et al.   TRENDS IN GENETICS

Pseudomonas aeruginosa: new insights into pathogenesis and host defenses

(2013) Shaan L. Gellatly et al.   Pathogens and Disease

Pathway-GPS and SIGORA: identifying relevant pathways based on the over-representation of their gene-pair signatures

(2013) Amir B.K. Foroushani et al.   PeerJ

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Synthetic Immunomodulatory Peptide IDR-1002 Enhances Monocyte Migration and Adhesion on Fibronectin

(2012) Laurence Madera et al.   Journal of Innate Immunity

Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective

(2012) Anders Folkesson et al.   NATURE REVIEWS MICROBIOLOGY

Effective Adjunctive Therapy by an Innate Defense Regulatory Peptide in a Preclinical Model of Severe Malaria

(2012) A. H. Achtman et al.   Science Translational Medicine

T-zone localized monocyte-derived dendritic cells promote Th1 priming to Salmonella

(2011) Adriana Flores-Langarica et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The role of matrix metalloproteinases in cystic fibrosis lung disease

(2011) A. Gaggar et al.   EUROPEAN RESPIRATORY JOURNAL

The emerging role of C/EBPs in glucocorticoid signaling: lessons from the lung

(2011) Abraham B Roos et al.   JOURNAL OF ENDOCRINOLOGY

Airway Epithelial MyD88 Restores Control of Pseudomonas aeruginosa Murine Infection via an IL-1-Dependent Pathway

(2011) L. A. Mijares et al.   JOURNAL OF IMMUNOLOGY

The extracellular matrix at a glance

(2010) C. Frantz et al.   JOURNAL OF CELL SCIENCE

TLR4 and TLR5 on Corneal Macrophages Regulate Pseudomonas aeruginosa Keratitis by Signaling through MyD88-Dependent and -Independent Pathways

(2010) Y. Sun et al.   JOURNAL OF IMMUNOLOGY

Synthetic Cationic Peptide IDR-1002 Provides Protection against Bacterial Infections through Chemokine Induction and Enhanced Leukocyte Recruitment

(2010) Anastasia Nijnik et al.   JOURNAL OF IMMUNOLOGY

Guidance molecules in lung cancer

(2010) Patrick Nasarre et al.   Cell Adhesion & Migration

Effects of an LL-37-Derived Antimicrobial Peptide in an Animal Model of Biofilm Pseudomonas Sinusitis

(2009) Sri Kiran Chennupati et al.   American Journal of Rhinology & Allergy

Pseudomonas aeruginosa in adults with chronic obstructive pulmonary disease

(2009) Timothy F Murphy   CURRENT OPINION IN PULMONARY MEDICINE

Urinary tract infections caused by Pseudomonas aeruginosa: A minireview

(2009) Rahul Mittal et al.   Journal of Infection and Public Health

Effect of IL-10 on Neutrophil Recruitment and Survival afterPseudomonas aeruginosaChallenge

(2008) Lei Sun et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Airway epithelial control of Pseudomonas aeruginosa infection in cystic fibrosis

(2008) Victoria L. Campodónico et al.   TRENDS IN MOLECULAR MEDICINE

Disease-Specific Gene Expression Profiling in Multiple Models of Lung Disease

(2007) Christina C. Lewis et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE