Peptide IDR-1018: modulating the immune system and targeting bacterial biofilms to treat antibiotic-resistant bacterial infections

A Broad-Spectrum Antibiofilm Peptide Enhances Antibiotic Action against Bacterial Biofilms

(2014) Fany Reffuveille et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Host defense peptides: front-line immunomodulators

(2014) Sarah C. Mansour et al.   TRENDS IN IMMUNOLOGY

Broad-Spectrum Anti-biofilm Peptide That Targets a Cellular Stress Response

(2014) César de la Fuente-Núñez et al.   PLoS Pathogens

Innate defense regulator peptide 1018 protects against perinatal brain injury

(2013) Hayde Bolouri et al.   ANNALS OF NEUROLOGY

Bacterial biofilm development as a multicellular adaptation: antibiotic resistance and new therapeutic strategies

(2013) César de la Fuente-Núñez et al.   CURRENT OPINION IN MICROBIOLOGY

Ability of Innate Defence Regulator Peptides IDR-1002, IDR-HH2 and IDR-1018 to Protect against Mycobacterium tuberculosis Infections in Animal Models

(2013) Bruno Rivas-Santiago et al.   PLoS One

Synthetic Cationic Peptide IDR-1018 Modulates Human Macrophage Differentiation

(2013) Olga M. Pena et al.   PLoS One

Biofilms and Inflammation in Chronic Wounds

(2013) Ge Zhao et al.   Advances in Wound Care

Inhibition of Bacterial Biofilm Formation and Swarming Motility by a Small Synthetic Cationic Peptide

(2012) César de la Fuente-Núñez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Innate Defense Regulator Peptide 1018 in Wound Healing and Wound Infection

(2012) Lars Steinstraesser et al.   PLoS One

Effective Adjunctive Therapy by an Innate Defense Regulatory Peptide in a Preclinical Model of Severe Malaria

(2012) A. H. Achtman et al.   Science Translational Medicine

The inflammatory response in sepsis

(2012) Markus Bosmann et al.   TRENDS IN IMMUNOLOGY

Staphylococcus aureus Biofilms Prevent Macrophage Phagocytosis and Attenuate Inflammation In Vivo

(2011) L. R. Thurlow et al.   JOURNAL OF IMMUNOLOGY

Extreme Antimicrobial Peptide and Polymyxin B Resistance in the Genus Burkholderia

(2011) Slade A. Loutet et al.   Frontiers in Microbiology

Structural Studies of a Peptide with Immune Modulating and Direct Antimicrobial Activity

(2010) Michal Wieczorek et al.   CHEMISTRY & BIOLOGY

Synthetic Cationic Peptide IDR-1002 Provides Protection against Bacterial Infections through Chemokine Induction and Enhanced Leukocyte Recruitment

(2010) Anastasia Nijnik et al.   JOURNAL OF IMMUNOLOGY

Systems biology evaluation of immune responses induced by human host defence peptide LL-37 in mononuclear cells

(2009) Neeloffer Mookherjee et al.   Molecular BioSystems

Staphylococcal biofilms impair wound healing by delaying reepithelialization in a murine cutaneous wound model

(2009) Clark F. Schierle et al.   WOUND REPAIR AND REGENERATION

Use of Artificial Intelligence in the Design of Small Peptide Antibiotics Effective against a Broad Spectrum of Highly Antibiotic-Resistant Superbugs

(2008) Artem Cherkasov et al.   ACS Chemical Biology

Human Host Defense Peptide LL-37 Prevents Bacterial Biofilm Formation

(2008) J. Overhage et al.   INFECTION AND IMMUNITY