标题
ABCG2: does resolving its structure elucidate the mechanism?
作者
关键词
-
出版物
BIOCHEMICAL SOCIETY TRANSACTIONS
Volume 46, Issue 6, Pages 1485-1494
出版商
Portland Press Ltd.
发表日期
2018-11-22
DOI
10.1042/bst20180145
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Residues contributing to drug transport by ABCG2 are localised to multiple drug-binding pockets
- (2018) Megan H. Cox et al. BIOCHEMICAL JOURNAL
- Structural basis of small-molecule inhibition of human multidrug transporter ABCG2
- (2018) Scott M. Jackson et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Antibiotic resistance ABCF proteins reset the peptidyl transferase centre of the ribosome to counter translational arrest
- (2018) Victoriia Murina et al. NUCLEIC ACIDS RESEARCH
- Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation
- (2018) Youngjin Kim et al. SCIENCE
- Structural basis of small-molecule inhibition of human multidrug transporter ABCG2
- (2018) Scott M. Jackson et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Polymorphisms of the multidrug pump ABCG2: a systematic review of their effect on protein expression, function and drug pharmacokinetics
- (2018) Niall Heyes et al. DRUG METABOLISM AND DISPOSITION
- ABCG2- and ABCG4-Mediated Efflux of Amyloid-β Peptide 1-40 at the Mouse Blood-Brain Barrier
- (2018) Tuan Minh Do et al. JOURNAL OF ALZHEIMERS DISEASE
- Structure of the human multidrug transporter ABCG2
- (2017) Nicholas M. I. Taylor et al. NATURE
- Structure-function relationships in ABCG2: insights from molecular dynamics simulations and molecular docking studies
- (2017) Ricardo J. Ferreira et al. Scientific Reports
- The structure of the human ABC transporter ABCG2 reveals a novel mechanism for drug extrusion
- (2017) Narakorn Khunweeraphong et al. Scientific Reports
- Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating
- (2017) Gregory M Martin et al. eLife
- A role for ABCG2 beyond drug transport: Regulation of autophagy
- (2016) Rui Ding et al. Autophagy
- The multidrug transporter ABCG2: still more questions than answers
- (2016) A. J. Horsey et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- A mechanism of viral immune evasion revealed by cryo-EM analysis of the TAP transporter
- (2016) Michael L. Oldham et al. NATURE
- Crystal structure of the human sterol transporter ABCG5/ABCG8
- (2016) Jyh-Yeuan Lee et al. NATURE
- Mechanistic diversity in ATP-binding cassette (ABC) transporters
- (2016) Kaspar P Locher NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Jump into a New Fold—A Homology Based Model for the ABCG2/BCRP Multidrug Transporter
- (2016) Laura László et al. PLoS One
- Mechanistic diversity in ATP-binding cassette (ABC) transporters
- (2016) Kaspar P Locher NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure of the transporter associated with antigen processing trapped by herpes simplex virus
- (2016) Michael L Oldham et al. eLife
- ABC transporter research: going strong 40 years on
- (2015) F. L. Theodoulou et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Identification of residues in ABCG2 affecting protein trafficking and drug transport, using co-evolutionary analysis of ABCG sequences
- (2015) A. J. Haider et al. BIOSCIENCE REPORTS
- How cryo-EM is revolutionizing structural biology
- (2015) Xiao-chen Bai et al. TRENDS IN BIOCHEMICAL SCIENCES
- Three-dimensional structure of the human breast cancer resistance protein (BCRP/ABCG2) in an inward-facing conformation
- (2015) Mark F. Rosenberg et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Role of the Breast Cancer Resistance Protein (BCRP/ABCG2) in Drug Transport—an Update
- (2014) Qingcheng Mao et al. AAPS Journal
- Detergent-free purification of ABC (ATP-binding-cassette) transporters
- (2014) Sonali Gulati et al. BIOCHEMICAL JOURNAL
- The ABC-F protein EttA gates ribosome entry into the translation elongation cycle
- (2014) Grégory Boël et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Association between the ABCG2 C421A polymorphism and Alzheimer's disease
- (2013) Ágnes Fehér et al. NEUROSCIENCE LETTERS
- Refined structures of mouse P-glycoprotein
- (2013) Jingzhi Li et al. PROTEIN SCIENCE
- Regional expression of the BCRP/ABCG2 transporter in term human placentas
- (2013) Naureen Memon et al. REPRODUCTIVE TOXICOLOGY
- Effects of the lipid environment, cholesterol and bile acids on the function of the purified and reconstituted human ABCG2 protein
- (2012) Ágnes Telbisz et al. BIOCHEMICAL JOURNAL
- Identification of Proline Residues in or near the Transmembrane Helices of the Human Breast Cancer Resistance Protein (BCRP/ABCG2) That Are Important for Transport Activity and Substrate Specificity
- (2011) Zhanglin Ni et al. BIOCHEMISTRY
- Membrane transporters in drug development
- (2010) NATURE REVIEWS DRUG DISCOVERY
- The Human Breast Cancer Resistance Protein (BCRP/ABCG2) Shows Conformational Changes with Mitoxantrone
- (2010) Mark F. Rosenberg et al. STRUCTURE
- The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter
- (2009) Erik Procko et al. FASEB JOURNAL
- Multidrug efflux pumps: The structures of prokaryotic ATP-binding cassette transporter efflux pumps and implications for our understanding of eukaryotic P-glycoproteins and homologues
- (2009) Ian D. Kerr et al. FEBS Journal
- Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout
- (2009) O. M. Woodward et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Physiological and pharmacological roles of ABCG2 (BCRP): Recent findings in Abcg2 knockout mice
- (2008) Maria L.H. Vlaming et al. ADVANCED DRUG DELIVERY REVIEWS
- Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2?
- (2008) Christopher A. McDevitt et al. FEBS Journal
- Homology modeling of breast cancer resistance protein (ABCG2)
- (2008) Eszter Hazai et al. JOURNAL OF STRUCTURAL BIOLOGY
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