标题
The Mucosal Vaccine Adjuvant LT(R192G/L211A) or dmLT
作者
关键词
-
出版物
mSphere
Volume 3, Issue 4, Pages -
出版商
American Society for Microbiology
发表日期
2018-07-24
DOI
10.1128/msphere.00215-18
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Preformulation studies with the Escherichia coli double mutant heat-labile toxin adjuvant for use in an oral vaccine
- (2017) Jessica A. White et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Adjuvant selection regulates gut migration and phenotypic diversity of antigen-specific CD4+ T cells following parenteral immunization
- (2017) D R Frederick et al. Mucosal Immunology
- Immunization with Salmonella Enteritidis secreting mucosal adjuvant labile toxin confers protection against wild type challenge via augmentation of CD3 + CD4 + T-cell proliferation and enhancement of IFN-γ, IL-6 and IL-10 expressions in chicken
- (2017) Jonathan Lalsiamthara et al. VACCINE
- Development of a candidate stabilizing formulation for bulk storage of a double mutant heat labile toxin (dmLT) protein based adjuvant
- (2017) Vishal M. Toprani et al. VACCINE
- Silk Fibroin Microneedles for Transdermal Vaccine Delivery
- (2017) Jordan A. Stinson et al. ACS Biomaterials-Science & Engineering
- Silk Fibroin Microneedles for Transdermal Vaccine Delivery
- (2017) Jordan A. Stinson et al. ACS Biomaterials Science & Engineering
- Immunogenicity and Protective Efficacy against Enterotoxigenic Escherichia coli Colonization following Intradermal, Sublingual, or Oral Vaccination with EtpA Adhesin
- (2016) Qingwei Luo et al. Clinical and Vaccine Immunology
- Highlights of the 8th International Conference on Vaccines for Enteric Diseases: the Scottish Encounter To Defeat Diarrheal Diseases
- (2016) Sharon M. Tennant et al. Clinical and Vaccine Immunology
- Induction of mucosal immune responses againstHelicobacter pyloriinfection after sublingual and intragastric route of immunization
- (2016) Louise Sjökvist Ottsjö et al. IMMUNOLOGY
- Trained immunity: A program of innate immune memory in health and disease
- (2016) M. G. Netea et al. SCIENCE
- Microbiota-Dependent Sequelae of Acute Infection Compromise Tissue-Specific Immunity
- (2015) Denise Morais da Fonseca et al. CELL
- Shigella Outer Membrane Protein PSSP-1 Is Broadly Protective against Shigella Infection
- (2015) Jae-Ouk Kim et al. Clinical and Vaccine Immunology
- Therapeutic Transcutaneous Immunization with a Band-Aid Vaccine Resolves Experimental Otitis Media
- (2015) Laura A. Novotny et al. Clinical and Vaccine Immunology
- Cholera Toxin, and the Related Nontoxic Adjuvants mmCT and dmLT, Promote Human Th17 Responses via Cyclic AMP–Protein Kinase A and Inflammasome-Dependent IL-1 Signaling
- (2015) Maximilian Larena et al. JOURNAL OF IMMUNOLOGY
- Conformational instability governed by disulfide bonds partitions the dominant from subdominant helper T-cell responses specific for HIV-1 envelope glycoprotein gp120
- (2015) Hong-Nam P. Nguyen et al. VACCINE
- The novel adjuvant dmLT promotes dose sparing, mucosal immunity and longevity of antibody responses to the inactivated polio vaccine in a murine model
- (2015) Elizabeth B. Norton et al. VACCINE
- Genetic Fusions of a CFA/I/II/IV MEFA (Multiepitope Fusion Antigen) and a Toxoid Fusion of Heat-Stable Toxin (STa) and Heat-Labile Toxin (LT) of Enterotoxigenic Escherichia coli (ETEC) Retain Broad Anti-CFA and Antitoxin Antigenicity
- (2015) Xiaosai Ruan et al. PLoS One
- Evaluating the A-Subunit of the Heat-Labile Toxin (LT) As an Immunogen and a Protective Antigen Against Enterotoxigenic Escherichia coli (ETEC)
- (2015) Elizabeth B. Norton et al. PLoS One
- Immunization with a Double-Mutant (R192G/L211A) of the Heat-Labile Enterotoxin of Escherichia coli Offers Partial Protection against Campylobacter jejuni in an Adult Mouse Intestinal Colonization Model
- (2015) M. John Albert et al. PLoS One
- Development and Preclinical Evaluation of a Trivalent, Formalin-Inactivated Shigella Whole-Cell Vaccine
- (2014) R. W. Kaminski et al. Clinical and Vaccine Immunology
- Intradermal Delivery of Shigella IpaB and IpaD Type III Secretion Proteins: Kinetics of Cell Recruitment and Antigen Uptake, Mucosal and Systemic Immunity, and Protection across Serotypes
- (2014) S. J. Heine et al. JOURNAL OF IMMUNOLOGY
- The immune response of two microbial antigens delivered intradermally, sublingually, or the combination thereof
- (2014) Sangun Lee et al. MICROBES AND INFECTION
- Safety and immunogenicity of an improved oral inactivated multivalent enterotoxigenic Escherichia coli (ETEC) vaccine administered alone and together with dmLT adjuvant in a double-blind, randomized, placebo-controlled Phase I study
- (2014) Anna Lundgren et al. VACCINE
- Serum and mucosal antibody responses to inactivated polio vaccine after sublingual immunization using a thermoresponsive gel delivery system
- (2014) Jessica A White et al. Human Vaccines & Immunotherapeutics
- Evaluation in Mice of a Conjugate Vaccine for Cholera Made from Vibrio cholerae O1 (Ogawa) O-Specific Polysaccharide
- (2014) Mohammad Murshid Alam et al. PLoS Neglected Tropical Diseases
- Safety and Immunogenicity of a Single Oral Dose of Recombinant Double Mutant Heat-Labile Toxin Derived from Enterotoxigenic Escherichia coli
- (2013) Samer S. El-Kamary et al. Clinical and Vaccine Immunology
- A Double Mutant Heat-Labile Toxin from Escherichia coli, LT(R192G/L211A), Is an Effective Mucosal Adjuvant for Vaccination against Helicobacter pylori Infection
- (2013) Louise Sjökvist Ottsjö et al. INFECTION AND IMMUNITY
- Development and preclinical evaluation of safety and immunogenicity of an oral ETEC vaccine containing inactivated E. coli bacteria overexpressing colonization factors CFA/I, CS3, CS5 and CS6 combined with a hybrid LT/CT B subunit antigen, administered alone and together with dmLT adjuvant
- (2013) J. Holmgren et al. VACCINE
- The A Subunit of Escherichia coli Heat-Labile Enterotoxin Functions as a Mucosal Adjuvant and Promotes IgG2a, IgA, and Th17 Responses to Vaccine Antigens
- (2012) Elizabeth B. Norton et al. INFECTION AND IMMUNITY
- The Adjuvant Double Mutant Escherichia coli Heat Labile Toxin Enhances IL-17A Production in Human T Cells Specific for Bacterial Vaccine Antigens
- (2012) Susannah Leach et al. PLoS One
- Bioencapsulation of the hepatitis B surface antigen and its use as an effective oral immunogen
- (2012) Celine A. Hayden et al. VACCINE
- A randomized control trial comparing immunogenicity, safety, and preference for self- versus nurse-administered intradermal influenza vaccine
- (2012) Brenda L. Coleman et al. VACCINE
- Kinetic analysis and evaluation of the mechanisms involved in the resolution of experimental nontypeable Haemophilus influenzae-induced otitis media after transcutaneous immunization
- (2012) Laura A. Novotny et al. VACCINE
- Characterization of a Mutant Escherichia coli Heat-Labile Toxin, LT(R192G/L211A), as a Safe and Effective Oral Adjuvant
- (2011) Elizabeth B. Norton et al. Clinical and Vaccine Immunology
- Defending the mucosa: adjuvant and carrier formulations for mucosal immunity
- (2011) Louise B Lawson et al. CURRENT OPINION IN IMMUNOLOGY
- Broadly Protective Shigella Vaccine Based on Type III Secretion Apparatus Proteins
- (2011) Francisco J. Martinez-Becerra et al. INFECTION AND IMMUNITY
- Escherichia coli Heat-Labile Enterotoxin Promotes Protective Th17 Responses against Infection by Driving Innate IL-1 and IL-23 Production
- (2011) C. F. Brereton et al. JOURNAL OF IMMUNOLOGY
- Transcutaneous immunization as preventative and therapeutic regimens to protect against experimental otitis media due to nontypeable Haemophilus influenzae
- (2011) L A Novotny et al. Mucosal Immunology
- Development of a Bacillus subtilis-Based Rotavirus Vaccine
- (2010) S. Lee et al. Clinical and Vaccine Immunology
- Options for Inactivation, Adjuvant, and Route of Topical Administration of a Killed, Unencapsulated Pneumococcal Whole-Cell Vaccine
- (2010) Y.-J. Lu et al. Clinical and Vaccine Immunology
- Prophylactic Administration of Bacterially Derived Immunomodulators Improves the Outcome of Influenza Virus Infection in a Murine Model
- (2010) E. B. Norton et al. JOURNAL OF VIROLOGY
- Proinflammatory T helper type 17 cells are effective B-cell helpers
- (2010) M. Mitsdoerffer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mucosal adjuvant activity of cholera toxin requires Th17 cells and protects against inhalation anthrax
- (2010) S. K. Datta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Antigen-specific Treg regulate Th17-mediated lung neutrophilic inflammation, B-cell recruitment and polymeric IgA and IgM levels in the airways
- (2009) Zeina Jaffar et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Cholera Toxin and Escherichia coli Heat-Labile Enterotoxin, but Not Their Nontoxic Counterparts, Improve the Antigen-Presenting Cell Function of Human B Lymphocytes
- (2009) D. R. M. Negri et al. INFECTION AND IMMUNITY
- Cutting Edge: Lung Mucosal Th17-Mediated Responses Induce Polymeric Ig Receptor Expression by the Airway Epithelium and Elevate Secretory IgA Levels
- (2009) Z. Jaffar et al. JOURNAL OF IMMUNOLOGY
- CD11chigh Dendritic Cells Are Essential for Activation of CD4+ T Cells and Generation of Specific Antibodies following Mucosal Immunization
- (2009) L. Fahlen-Yrlid et al. JOURNAL OF IMMUNOLOGY
- Kinetics of Immune Responses to Influenza Virus-Like Particles and Dose-Dependence of Protection with a Single Vaccination
- (2009) F. S. Quan et al. JOURNAL OF VIROLOGY
- Interleukin 17 acts in synergy with B cell–activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus
- (2009) Agnès Doreau et al. NATURE IMMUNOLOGY
- Intranasal Delivery of Cholera Toxin Induces Th17-Dominated T-Cell Response to Bystander Antigens
- (2009) Jee-Boong Lee et al. PLoS One
- Transient Facial Nerve Paralysis (Bell's Palsy) following Intranasal Delivery of a Genetically Detoxified Mutant of Escherichia coli Heat Labile Toxin
- (2009) David J. M. Lewis et al. PLoS One
- Elevated cyclic AMP and PDE4 inhibition induce chemokine expression in human monocyte-derived macrophages
- (2009) A. L. Hertz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started