标题
Remyelination Therapy in Multiple Sclerosis
作者
关键词
-
出版物
Frontiers in Neurology
Volume 6, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2015-12-13
DOI
10.3389/fneur.2015.00257
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cerebrospinal fluid proteomics in multiple sclerosis
- (2015) Ann C. Kroksveen et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Astrocytic TYMP and VEGFA drive blood–brain barrier opening in inflammatory central nervous system lesions
- (2015) Candice Chapouly et al. BRAIN
- Silencing IFN-γ Binding/Signaling in Astrocytes versus Microglia Leads to Opposite Effects on Central Nervous System Autoimmunity
- (2015) Xiaoli Ding et al. JOURNAL OF IMMUNOLOGY
- Demyelination Causes Adult CNS Progenitors to Revert to an Immature State and Express Immune Cues That Support Their Migration
- (2015) S. Moyon et al. JOURNAL OF NEUROSCIENCE
- Deletion of Mitochondrial Anchoring Protects Dysmyelinating Shiverer: Implications for Progressive MS
- (2015) D. C. Joshi et al. JOURNAL OF NEUROSCIENCE
- Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo
- (2015) Fadi J. Najm et al. NATURE
- SEMA4D compromises blood–brain barrier, activates microglia, and inhibits remyelination in neurodegenerative disease
- (2015) Ernest S. Smith et al. NEUROBIOLOGY OF DISEASE
- Focal disturbances in the blood–brain barrier are associated with formation of neuroinflammatory lesions
- (2015) Jorge Ivan Alvarez et al. NEUROBIOLOGY OF DISEASE
- Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic
- (2015) Sharon W. Way et al. Nature Communications
- The use of transcranial magnetic stimulation in diagnosis, prognostication and treatment evaluation in multiple sclerosis
- (2015) Marion Simpson et al. Multiple Sclerosis and Related Disorders
- Measuring longitudinal myelin water fraction in new multiple sclerosis lesions
- (2015) Wendy S. Vargas et al. NeuroImage-Clinical
- The Neurophysiologist Perspective into MS Plasticity
- (2015) Elise Houdayer et al. Frontiers in Neurology
- Simple MRI Metrics Contribute to Optimal Care of the Patient with Multiple Sclerosis
- (2014) J. H. Simon et al. AMERICAN JOURNAL OF NEURORADIOLOGY
- The vestibular evoked myogenic potentials (VEMP) score: a promising tool for evaluation of brainstem involvement in multiple sclerosis
- (2014) T. Gabelić et al. EUROPEAN JOURNAL OF NEUROLOGY
- Genetic inactivation of PERK signaling in mouse oligodendrocytes: Normal developmental myelination with increased susceptibility to inflammatory demyelination
- (2014) Yassir Hussien et al. GLIA
- Acid-sensing ion channels promote the inflammation and migration of cultured rat microglia
- (2014) Xiao-Wei Yu et al. GLIA
- Interaction of mTOR and Erk1/2 signaling to regulate oligodendrocyte differentiation
- (2014) JinXiang Dai et al. GLIA
- Direct and Indirect Effects of Immune and Central Nervous System–Resident Cells on Human Oligodendrocyte Progenitor Cell Differentiation
- (2014) Craig S. Moore et al. JOURNAL OF IMMUNOLOGY
- A randomized placebo-controlled phase III trial of oral laquinimod for multiple sclerosis
- (2014) T. L. Vollmer et al. JOURNAL OF NEUROLOGY
- Imaging outcomes for trials of remyelination in multiple sclerosis
- (2014) Shahrukh Mallik et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Astrocyte-Derived BDNF Supports Myelin Protein Synthesis after Cuprizone-Induced Demyelination
- (2014) C. G. Fulmer et al. JOURNAL OF NEUROSCIENCE
- Conditional Ablation of Raptor or Rictor Has Differential Impact on Oligodendrocyte Differentiation and CNS Myelination
- (2014) K. K. Bercury et al. JOURNAL OF NEUROSCIENCE
- Mammalian Target of Rapamycin Promotes Oligodendrocyte Differentiation, Initiation and Extent of CNS Myelination
- (2014) S. E. Wahl et al. JOURNAL OF NEUROSCIENCE
- Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis
- (2014) Feng Mei et al. NATURE MEDICINE
- Mitochondrial immobilization mediated by syntaphilin facilitates survival of demyelinated axons
- (2014) Nobuhiko Ohno et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Imaging of repeated episodes of demyelination and remyelination in multiple sclerosis
- (2014) Robert A. Brown et al. NeuroImage-Clinical
- Laquinimod reduces neuroaxonal injury through inhibiting microglial activation
- (2014) Manoj Kumar Mishra et al. Annals of Clinical and Translational Neurology
- Astroglial PGC-1alpha increases mitochondrial antioxidant capacity and suppresses inflammation: implications for multiple sclerosis
- (2014) Philip G Nijland et al. Acta Neuropathologica Communications
- Hyaluronan accumulation and arrested oligodendrocyte progenitor maturation in vanishing white matter disease
- (2013) Marianna Bugiani et al. BRAIN
- Targeting ASIC1 in primary progressive multiple sclerosis: evidence of neuroprotection with amiloride
- (2013) Tarunya Arun et al. BRAIN
- Fibronectin aggregation in multiple sclerosis lesions impairs remyelination
- (2013) Josephine M. J. Stoffels et al. BRAIN
- Sema4D Knockdown in Oligodendrocytes Promotes Functional Recovery After Spinal Cord Injury
- (2013) Hong-Lei Zhang et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Quetiapine Fumarate for the Treatment of Multiple Sclerosis: Focus on Myelin Repair
- (2013) Simon Zhornitsky et al. CNS Neuroscience & Therapeutics
- Cell-Based Reparative Therapies for Multiple Sclerosis
- (2013) Tamir Ben-Hur et al. Current Neurology and Neuroscience Reports
- The role of myelin and oligodendrocytes in axonal energy metabolism
- (2013) Aiman S Saab et al. CURRENT OPINION IN NEUROBIOLOGY
- Ageing stem and progenitor cells: implications for rejuvenation of the central nervous system
- (2013) P. van Wijngaarden et al. DEVELOPMENT
- Inhibitors of myelination: ECM changes, CSPGs and PTPs
- (2013) Danielle E. Harlow et al. EXPERIMENTAL NEUROLOGY
- Cellular targets and mechanistic strategies of remyelination-promoting IgMs as part of the naturally occurring autoantibody repertoire
- (2013) Jens O Watzlawik et al. Expert Review of Neurotherapeutics
- Nutritional factors and aging in demyelinating diseases
- (2013) Ana M. Adamo Genes and Nutrition
- Astrocytes play a key role in EAE pathophysiology by orchestrating in the CNS the inflammatory response of resident and peripheral immune cells and by suppressing remyelination
- (2013) Roberta Brambilla et al. GLIA
- Placebo-controlled trial of oral laquinimod in multiple sclerosis: MRI evidence of an effect on brain tissue damage
- (2013) M. Filippi et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Signaling through ERK1/2 Controls Myelin Thickness during Myelin Repair in the Adult Central Nervous System
- (2013) S. L. Fyffe-Maricich et al. JOURNAL OF NEUROSCIENCE
- Oligodendrocyte-Specific Activation of PERK Signaling Protects Mice against Experimental Autoimmune Encephalomyelitis
- (2013) W. Lin et al. JOURNAL OF NEUROSCIENCE
- A regenerative approach to the treatment of multiple sclerosis
- (2013) Vishal A. Deshmukh et al. NATURE
- Pathophysiology of the brain extracellular matrix: a new target for remyelination
- (2013) Lorraine W. Lau et al. NATURE REVIEWS NEUROSCIENCE
- Myelin-based inhibitors of oligodendrocyte myelination: clues from axonal growth and regeneration
- (2013) Feng Mei et al. Neuroscience Bulletin
- Therapeutic laquinimod treatment decreases inflammation, initiates axon remyelination, and improves motor deficit in a mouse model of multiple sclerosis
- (2013) Spencer Moore et al. Brain and Behavior
- Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination
- (2012) Wolfgang Brück et al. ACTA NEUROPATHOLOGICA
- Endogeneous Remyelination: Findings in Human Studies
- (2012) Markus Kipp et al. CNS & Neurological Disorders-Drug Targets
- Chondroitinase ABC promotes compensatory sprouting of the intact corticospinal tract and recovery of forelimb function following unilateral pyramidotomy in adult mice
- (2012) Michelle L. Starkey et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Laquinimod modulates B cells and their regulatory effects on T cells in Multiple Sclerosis
- (2012) Elias Toubi et al. JOURNAL OF NEUROIMMUNOLOGY
- ERK1/ERK2 MAPK Signaling is Required to Increase Myelin Thickness Independent of Oligodendrocyte Differentiation and Initiation of Myelination
- (2012) A. Ishii et al. JOURNAL OF NEUROSCIENCE
- T2prep three-dimensional spiral imaging with efficient whole brain coverage for myelin water quantification at 1.5 tesla
- (2012) Thanh D. Nguyen et al. MAGNETIC RESONANCE IN MEDICINE
- On the inherent precision of mcDESPOT
- (2012) Christopher L. Lankford et al. MAGNETIC RESONANCE IN MEDICINE
- Laquinimod prevents inflammation-induced synaptic alterations occurring in experimental autoimmune encephalomyelitis
- (2012) Francesca Ruffini et al. Multiple Sclerosis Journal
- Oligodendroglia metabolically support axons and contribute to neurodegeneration
- (2012) Youngjin Lee et al. NATURE
- Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity
- (2012) Ursula Fünfschilling et al. NATURE
- Neuroprotection and repair in multiple sclerosis
- (2012) Robin J. M. Franklin et al. Nature Reviews Neurology
- Rapid whole cerebrum myelin water imaging using a 3D GRASE sequence
- (2012) Thomas Prasloski et al. NEUROIMAGE
- Placebo-Controlled Trial of Oral Laquinimod for Multiple Sclerosis
- (2012) Giancarlo Comi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Chondroitinase and Growth Factors Enhance Activation and Oligodendrocyte Differentiation of Endogenous Neural Precursor Cells after Spinal Cord Injury
- (2012) Soheila Karimi-Abdolrezaee et al. PLoS One
- Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation
- (2012) Dimitrios Davalos et al. Nature Communications
- Olesoxime accelerates myelination and promotes repair in models of demyelination
- (2011) Karine Magalon et al. ANNALS OF NEUROLOGY
- Class 3 semaphorins influence oligodendrocyte precursor recruitment and remyelination in adult central nervous system
- (2011) Gabrièle Piaton et al. BRAIN
- Quantification of increased cellularity during inflammatory demyelination
- (2011) Yong Wang et al. BRAIN
- Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis
- (2011) Jessica L. Zambonin et al. BRAIN
- Distinct Spatio-Temporal Extracellular Matrix Accumulation within Demyelinated Spinal Cord Lesions in Theiler's Murine Encephalomyelitis
- (2011) Verena Haist et al. BRAIN PATHOLOGY
- Muscarinic receptor subtypes as potential targets to modulate oligodendrocyte progenitor survival, proliferation, and differentiation
- (2011) Federica De Angelis et al. Developmental Neurobiology
- Is the magnetization transfer ratio a marker for myelin in multiple sclerosis?
- (2011) Irene M. Vavasour et al. JOURNAL OF MAGNETIC RESONANCE IMAGING
- Inhibition of CNS Remyelination by the Presence of Semaphorin 3A
- (2011) Y. A. Syed et al. JOURNAL OF NEUROSCIENCE
- The ERK2 Mitogen-Activated Protein Kinase Regulates the Timing of Oligodendrocyte Differentiation
- (2011) S. L. Fyffe-Maricich et al. JOURNAL OF NEUROSCIENCE
- 3D FLAIRED: 3D fluid attenuated inversion recovery for enhanced detection of lesions in multiple sclerosis
- (2011) Paul Polak et al. MAGNETIC RESONANCE IN MEDICINE
- Sema4D as an inhibitory regulator in oligodendrocyte development
- (2011) Wataru Yamaguchi et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Expression profiles of endoplasmic reticulum stress-related molecules in demyelinating lesions and multiple sclerosis
- (2011) Paula Cunnea et al. Multiple Sclerosis Journal
- Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination
- (2011) Stephen P J Fancy et al. NATURE NEUROSCIENCE
- Myelin water imaging reflects clinical variability in multiple sclerosis
- (2011) Shannon Kolind et al. NEUROIMAGE
- Selective Inhibition of a Regulatory Subunit of Protein Phosphatase 1 Restores Proteostasis
- (2011) P. Tsaytler et al. SCIENCE
- Measuring Myelin Repair and Axonal Loss with Diffusion Tensor Imaging
- (2010) R.J. Fox et al. AMERICAN JOURNAL OF NEURORADIOLOGY
- Imaging central nervous system myelin by positron emission tomography in multiple sclerosis using [methyl-11C]-2-(4′-methylaminophenyl)- 6-hydroxybenzothiazole
- (2010) Bruno Stankoff et al. ANNALS OF NEUROLOGY
- Extracellular Matrix in Multiple Sclerosis Lesions: Fibrillar Collagens, Biglycan and Decorin are Upregulated and Associated with Infiltrating Immune Cells
- (2010) Hema Mohan et al. BRAIN PATHOLOGY
- Age-Related and Cuprizone-Induced Changes in Myelin and Transcription Factor Gene Expression and in Oligodendrocyte Cell Densities in the Rostral Corpus Callosum of Mice
- (2010) J. Ronald Doucette et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Astrocyte-Restricted Ablation of Interleukin-17-Induced Act1-Mediated Signaling Ameliorates Autoimmune Encephalomyelitis
- (2010) Zizhen Kang et al. IMMUNITY
- Laquinimod interferes with migratory capacity of T cells and reduces IL-17 levels, inflammatory demyelination and acute axonal damage in mice with experimental autoimmune encephalomyelitis
- (2010) Christiane Wegner et al. JOURNAL OF NEUROIMMUNOLOGY
- Wnts Influence the Timing and Efficiency of Oligodendrocyte Precursor Cell Generation in the Telencephalon
- (2010) A. J. Langseth et al. JOURNAL OF NEUROSCIENCE
- Demyelination Increases Axonal Stationary Mitochondrial Size and the Speed of Axonal Mitochondrial Transport
- (2010) S. Kiryu-Seo et al. JOURNAL OF NEUROSCIENCE
- Reproducibility of quantitative magnetization-transfer imaging parameters from repeated measurements
- (2010) Ives R. Levesque et al. MAGNETIC RESONANCE IN MEDICINE
- Two-year study of cervical cord volume and myelin water in primary progressive multiple sclerosis
- (2010) C. Laule et al. Multiple Sclerosis Journal
- Retinoid X receptor gamma signaling accelerates CNS remyelination
- (2010) Jeffrey K Huang et al. NATURE NEUROSCIENCE
- Myelination and the trophic support of long axons
- (2010) Klaus-Armin Nave NATURE REVIEWS NEUROSCIENCE
- Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2
- (2010) J. A. Sloane et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Silencing Nogo-A promotes functional recovery in demyelinating disease
- (2009) Yuhong Yang et al. ANNALS OF NEUROLOGY
- Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells
- (2009) Sha Mi et al. ANNALS OF NEUROLOGY
- Measuring Demyelination and Remyelination in Acute Multiple Sclerosis Lesion Voxels
- (2009) Paul S. Giacomini et al. ARCHIVES OF NEUROLOGY
- Mitochondrial changes within axons in multiple sclerosis
- (2009) D. J. Mahad et al. BRAIN
- Gender and sex hormones in multiple sclerosis pathology and therapy
- (2009) Arnaud Nicot Frontiers in Bioscience-Landmark
- Impact of sex steroids on neuroinflammatory processes and experimental multiple sclerosis
- (2009) Markus Kipp et al. FRONTIERS IN NEUROENDOCRINOLOGY
- Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS
- (2009) S. P.J. Fancy et al. GENES & DEVELOPMENT
- Transgenic Inhibition of Astroglial NF- B Improves Functional Outcome in Experimental Autoimmune Encephalomyelitis by Suppressing Chronic Central Nervous System Inflammation
- (2009) R. Brambilla et al. JOURNAL OF IMMUNOLOGY
- Increased Expression of Endoplasmic Reticulum Stress-Related Signaling Pathway Molecules in Multiple Sclerosis Lesions
- (2009) Aoife Ní Mháille et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Activation of the Mammalian Target of Rapamycin (mTOR) Is Essential for Oligodendrocyte Differentiation
- (2009) W. A. Tyler et al. JOURNAL OF NEUROSCIENCE
- Akt Signals through the Mammalian Target of Rapamycin Pathway to Regulate CNS Myelination
- (2009) S. P. Narayanan et al. JOURNAL OF NEUROSCIENCE
- Sema4D deficiency results in an increase in the number of oligodendrocytes in healthy and injured mouse brains
- (2009) Yoshitaka Taniguchi et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Quantitative magnetization transfer measured pool-size ratio reflects optic nerve myelin content in ex vivo mice
- (2009) Xiawei Ou et al. MAGNETIC RESONANCE IN MEDICINE
- About “axial” and “radial” diffusivities
- (2009) Claudia A.M. Wheeler-Kingshott et al. MAGNETIC RESONANCE IN MEDICINE
- Wnt signaling is sufficient to perturb oligodendrocyte maturation
- (2009) Keith Feigenson et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin–TCF interaction
- (2009) Feng Ye et al. NATURE NEUROSCIENCE
- Neurite density from magnetic resonance diffusion measurements at ultrahigh field: Comparison with light microscopy and electron microscopy
- (2009) Sune N. Jespersen et al. NEUROIMAGE
- Optical coherence tomography is less sensitive than visual evoked potentials in optic neuritis
- (2009) R. T. Naismith et al. NEUROLOGY
- Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination
- (2009) Yueting Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Magnetization transfer ratio evolution with demyelination and remyelination in multiple sclerosis lesions
- (2008) Jacqueline T. Chen et al. ANNALS OF NEUROLOGY
- Astrocytes in multiple sclerosis: A product of their environment
- (2008) A. Nair et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Constitutively Active Akt Induces Enhanced Myelination in the CNS
- (2008) A. I. Flores et al. JOURNAL OF NEUROSCIENCE
- Taking ageing into account in remyelination-based therapies for multiple sclerosis
- (2008) Julia M. Rist et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Effect of laquinimod on MRI-monitored disease activity in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study
- (2008) G Comi et al. LANCET
- Quantitative magnetic resonance of postmortem multiple sclerosis brain before and after fixation
- (2008) Klaus Schmierer et al. MAGNETIC RESONANCE IN MEDICINE
- Outcome measures for trials of remyelinating agents in multiple sclerosis: retrospective longitudinal analysis of visual evoked potential latency
- (2008) A Niklas et al. Multiple Sclerosis Journal
- Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency
- (2008) Siming Shen et al. NATURE NEUROSCIENCE
- Cytokines and Myelination in the Central Nervous System
- (2008) Thomas Schmitz et al. TheScientificWorldJOURNAL
- Regeneration and repair in multiple sclerosis: The view of experimental pathology
- (2007) W.F. Blakemore JOURNAL OF THE NEUROLOGICAL SCIENCES
- Myelin water imaging of multiple sclerosis at 7 T: Correlations with histopathology
- (2007) Cornelia Laule et al. NEUROIMAGE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation