Neuroprotection and repair in multiple sclerosis

NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

(2012) Marie T. Fischer et al.   BRAIN

Rejuvenation of Regeneration in the Aging Central Nervous System

(2012) Julia M. Ruckh et al.   Cell Stem Cell

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Assembly and Maintenance of Nodes of Ranvier Rely on Distinct Sources of Proteins and Targeting Mechanisms

(2012) Yanqing Zhang et al.   NEURON

Axonal transport deficits and degeneration can evolve independently in mouse models of amyotrophic lateral sclerosis

(2012) P. Marinkovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ApoE-Directed Therapeutics Rapidly Clear  -Amyloid and Reverse Deficits in AD Mouse Models

(2012) P. E. Cramer et al.   SCIENCE

Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis

(2011) Ajit Singh Dhaunchak et al.   ANNALS OF NEUROLOGY

Class 3 semaphorins influence oligodendrocyte precursor recruitment and remyelination in adult central nervous system

(2011) Gabrièle Piaton et al.   BRAIN

Newly lesioned tissue in multiple sclerosis--a role for oxidative damage?

(2011) K. J. Smith   BRAIN

Enhancing remyelination in disease--can we wrap it up?

(2011) M. R. Kotter et al.   BRAIN

Oxidative damage in multiple sclerosis lesions

(2011) L. Haider et al.   BRAIN

Sodium channels and microglial function

(2011) Joel A. Black et al.   EXPERIMENTAL NEUROLOGY

Genetically Induced Adult Oligodendrocyte Cell Death Is Associated with Poor Myelin Clearance, Reduced Remyelination, and Axonal Damage

(2011) H. B. F. Pohl et al.   JOURNAL OF NEUROSCIENCE

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis

(2011) Ivana Nikić et al.   NATURE MEDICINE

Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination

(2011) Stephen P J Fancy et al.   NATURE NEUROSCIENCE

Myelin Regeneration in Multiple Sclerosis: Targeting Endogenous Stem Cells

(2011) Jeffrey K. Huang et al.   Neurotherapeutics

The axo-myelinic synapse

(2011) Peter K. Stys   TRENDS IN NEUROSCIENCES

Hypoxia. 2. Hypoxia regulates cellular metabolism

(2010) William W. Wheaton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Kinetic model of the inhibition of respiration by endogenous nitric oxide in intact cells

(2010) Enara Aguirre et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Radical changes in multiple sclerosis pathogenesis

(2010) Jack van Horssen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

CNS-Resident Glial Progenitor/Stem Cells Produce Schwann Cells as well as Oligodendrocytes during Repair of CNS Demyelination

(2010) Malgorzata Zawadzka et al.   Cell Stem Cell

Evolution of Clinical and Molecular Responses to Bexarotene Treatment in Cutaneous T-Cell Lymphoma

(2010) F. Ballanger et al.   DERMATOLOGY

Overcoming remyelination failure in multiple sclerosis and other myelin disorders

(2010) Stephen P.J. Fancy et al.   EXPERIMENTAL NEUROLOGY

Kinesin I Transports Tetramerized Kv3 Channels through the Axon Initial Segment via Direct Binding

(2010) M. Xu et al.   JOURNAL OF NEUROSCIENCE

Demyelination Increases Axonal Stationary Mitochondrial Size and the Speed of Axonal Mitochondrial Transport

(2010) S. Kiryu-Seo et al.   JOURNAL OF NEUROSCIENCE

Lamotrigine for neuroprotection in secondary progressive multiple sclerosis: a randomised, double-blind, placebo-controlled, parallel-group trial

(2010) Raju Kapoor et al.   LANCET NEUROLOGY

Retinoid X receptor gamma signaling accelerates CNS remyelination

(2010) Jeffrey K Huang et al.   NATURE NEUROSCIENCE

Myelination and the trophic support of long axons

(2010) Klaus-Armin Nave   NATURE REVIEWS NEUROSCIENCE

Mechanisms of neuronal dysfunction and degeneration in multiple sclerosis

(2010) Ranjan Dutta et al.   PROGRESS IN NEUROBIOLOGY

Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells

(2009) Sha Mi et al.   ANNALS OF NEUROLOGY

Mitochondrial changes within axons in multiple sclerosis

(2009) D. J. Mahad et al.   BRAIN

The relation between inflammation and neurodegeneration in multiple sclerosis brains

(2009) Josa M. Frischer et al.   BRAIN

Molecular Changes in White Matter Adjacent to an Active Demyelinating Lesion in Early Multiple Sclerosis

(2009) Thomas Zeis et al.   BRAIN PATHOLOGY

The role of CNS glia in preserving axon function

(2009) Julia M Edgar et al.   CURRENT OPINION IN NEUROBIOLOGY

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

(2009) S. P.J. Fancy et al.   GENES & DEVELOPMENT

Axonal Protective Effects of the Myelin-Associated Glycoprotein

(2009) T. Nguyen et al.   JOURNAL OF NEUROSCIENCE

Axonal Transport Defects in Neurodegenerative Diseases

(2009) G. A. Morfini et al.   JOURNAL OF NEUROSCIENCE

Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis

(2009) Bruce D Trapp et al.   LANCET NEUROLOGY

Remyelination capacity of the MS brain decreases with disease chronicity

(2009) T. Goldschmidt et al.   NEUROLOGY

Extensive remyelination of the CNS leads to functional recovery

(2009) I. D. Duncan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple Sclerosis: An Immune or Neurodegenerative Disorder?

(2008) Bruce D. Trapp et al.   Annual Review of Neuroscience

Severely dystrophic axons at amyloid plaques remain continuous and connected to viable cell bodies

(2008) Robert Adalbert et al.   BRAIN

Mitochondrial defects in acute multiple sclerosis lesions

(2008) Don Mahad et al.   BRAIN

LINGO-1 antagonists as therapy for multiple sclerosis:in vitroandin vivoevidence

(2008) Richard A Rudick et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Taking ageing into account in remyelination-based therapies for multiple sclerosis

(2008) Julia M. Rist et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency

(2008) Siming Shen et al.   NATURE NEUROSCIENCE

Remyelination in the CNS: from biology to therapy

(2008) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE

Review: Mitochondria and disease progression in multiple sclerosis

(2008) D. Mahad et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

The role of SVZ-derived neural precursors in demyelinating diseases: From animal models to multiple sclerosis

(2007) B. Nait-Oumesmar et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES