Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent

Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo

(2012) Joy X. Jiang et al.   FREE RADICAL BIOLOGY AND MEDICINE

The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91phox mediate hepatic fibrosis in mice

(2011) Yong-Han Paik et al.   HEPATOLOGY

NOX1/nicotinamide adenine dinucleotide phosphate, reduced form (NADPH) oxidase promotes proliferation of stellate cells and aggravates liver fibrosis induced by bile duct ligation

(2011) Wenhao Cui et al.   HEPATOLOGY

Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases

(2011) Jeffrey L. Barnes et al.   KIDNEY INTERNATIONAL

Scraping fibrosis: Expressway to the core of fibrosis

(2011) Wajahat Z Mehal et al.   NATURE MEDICINE

Managing patients with hepatitis-B-related or hepatitis-C-related decompensated cirrhosis

(2011) Scott A. Fink et al.   Nature Reviews Gastroenterology & Hepatology

Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis

(2010) Samuele De Minicis et al.   HEPATOLOGY

CX3CL1-CX3CR1 interaction prevents carbon tetrachloride-induced liver inflammation and fibrosis in mice

(2010) Tomonori Aoyama et al.   HEPATOLOGY

First in Class, Potent, and Orally Bioavailable NADPH Oxidase Isoform 4 (Nox4) Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis

(2010) Benoı̂t Laleu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Monitoring systemic oxidative stress in an animal model of amyotrophic lateral sclerosis

(2010) Francisco Javier Miana-Mena et al.   JOURNAL OF NEUROLOGY

NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGF 1-induced fibroblast differentiation into myofibroblasts

(2010) N. Amara et al.   THORAX

Effects of losartan on hepatic expression of nonphagocytic NADPH oxidase and fibrogenic genes in patients with chronic hepatitis C

(2009) Jordi Colmenero et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Nox proteins in signal transduction

(2009) David I. Brown et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pioglitazone promotes survival and prevents hepatic regeneration failure after partial hepatectomy in obese and diabetic KK-Ay mice

(2009) Tomonori Aoyama et al.   HEPATOLOGY

Targeting liver fibrosis: Strategies for development and validation of antifibrotic therapies

(2009) Yury Popov et al.   HEPATOLOGY

Advanced glycation end products induce production of reactive oxygen species via the activation of NADPH oxidase in murine hepatic stellate cells

(2009) Eduardo L.M. Guimarães et al.   JOURNAL OF HEPATOLOGY

NAD(P)H Oxidase Mediates TGF- 1-Induced Activation of Kidney Myofibroblasts

(2009) C. D. Bondi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

(2009) Louise Hecker et al.   NATURE MEDICINE

Phosphorylated Smad2/3 immunoreactivity in sporadic and familial amyotrophic lateral sclerosis and its mouse model

(2008) Masataka Nakamura et al.   ACTA NEUROPATHOLOGICA

Nox-2 Is a Modulator of Fibrogenesis in Kidney Allografts

(2008) A. Djamali et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Non-Cell-Autonomous Effect of Human SOD1G37R Astrocytes on Motor Neurons Derived from Human Embryonic Stem Cells

(2008) Maria C.N. Marchetto et al.   Cell Stem Cell

RXR agonists inhibit high-glucose-induced oxidative stress by repressing PKC activity in human endothelial cells

(2008) Dajun Chai et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Reduced nicotinamide adenine dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells

(2008) Samuele De Minicis et al.   HEPATOLOGY