Battle against RNA oxidation: molecular mechanisms for reducing oxidized RNA to protect cells

An RNA Degradation Machine Sculpted by Ro Autoantigen and Noncoding RNA

(2013) Xinguo Chen et al.   CELL

Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function

(2013) J. Ross Buchan et al.   CELL

Elimination and Utilization of Oxidized Guanine Nucleotides in the Synthesis of RNA and Its Precursors

(2013) Takeshi Sekiguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mycobacterium tuberculosisMutT1 (Rv2985) and ADPRase (Rv1700) Proteins Constitute a Two-stage Mechanism of 8-Oxo-dGTP and 8-Oxo-GTP Detoxification and Adenosine to Cytidine Mutation Avoidance

(2013) Aravind Goud G. Patil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The task force that rescues stalled ribosomes in bacteria

(2013) Emmanuel Giudice et al.   TRENDS IN BIOCHEMICAL SCIENCES

Human and Methodological Sources of Variability in the Measurement of Urinary 8-Oxo-7,8-dihydro-2′-deoxyguanosine

(2012) Lars Barregard et al.   ANTIOXIDANTS & REDOX SIGNALING

Characterization of RNA damage under oxidative stress in Escherichia coli

(2012) Min Liu et al.   BIOLOGICAL CHEMISTRY

Global analysis of RNA oxidation in Saccharomyces cerevisiae

(2012) Anastasia McKinlay et al.   BIOTECHNIQUES

Association Between Urinary Markers of Nucleic Acid Oxidation and Mortality in Type 2 Diabetes: A population-based cohort study

(2012) K. Broedbaek et al.   DIABETES CARE

TheYersinia pseudotuberculosisdegradosome is required for oxidative stress, while its PNPase subunit plays a degradosome-independent role in cold growth

(2012) Amanda Henry et al.   FEMS MICROBIOLOGY LETTERS

RNA modifications by oxidation: A novel disease mechanism?

(2012) Henrik E. Poulsen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Human MTH3 (NUDT18) Protein Hydrolyzes Oxidized Forms of Guanosine and Deoxyguanosine Diphosphates

(2012) Yasumitsu Takagi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Earliest Stage of Cognitive Impairment in Transition From Normal Aging to Alzheimer Disease Is Marked by Prominent RNA Oxidation in Vulnerable Neurons

(2012) Akihiko Nunomura et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Direct Strand Scission in Double Stranded RNA via a C5-Pyrimidine Radical

(2012) Marino J. E. Resendiz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Involvement of pnp in survival of UV radiation in Escherichia coli K-12

(2012) D. Rath et al.   MICROBIOLOGY-SGM

Nucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells

(2012) Lisa Lirussi et al.   MOLECULAR BIOLOGY OF THE CELL

Oxidative Damage to RNA in Aging and Neurodegenerative Disorders

(2012) Akihiko Nunomura et al.   NEUROTOXICITY RESEARCH

LRPPRC/SLIRP suppresses PNPase-mediated mRNA decay and promotes polyadenylation in human mitochondria

(2012) Takeshi Chujo et al.   NUCLEIC ACIDS RESEARCH

Quantification of oxidized levels of specific RNA species using an aldehyde reactive probe

(2011) Mikiei Tanaka et al.   ANALYTICAL BIOCHEMISTRY

tRNA structural and functional changes induced by oxidative stress

(2011) Barbara Nawrot et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Urinary Markers of Nucleic Acid Oxidation and Long-Term Mortality of Newly Diagnosed Type 2 Diabetic Patients

(2011) K. Broedbaek et al.   DIABETES CARE

Novel Mechanism of RNA Repair by RtcB via Sequential 2′,3′-Cyclic Phosphodiesterase and 3′-Phosphate/5′-Hydroxyl Ligation Reactions

(2011) Naoko Tanaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of mitochondria in neurodegenerative diseases

(2011) Massimiliano Filosto et al.   JOURNAL OF NEUROLOGY

tRNAs Marked with CCACCA Are Targeted for Degradation

(2011) J. E. Wilusz et al.   SCIENCE

RNA toxins: mediators of stress adaptation and pathogen defense

(2011) Alice Zhabokritsky et al.   Wiley Interdisciplinary Reviews-RNA

Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress

(2010) Hiroshi Hayakawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxidative damage to RNA: mechanisms, consequences, and diseases

(2010) Qiongman Kong et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Direct Strand Scission from a Nucleobase Radical in RNA

(2010) Aaron C. Jacobs et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Human polynucleotide phosphorylase (hPNPase old-35 ): an evolutionary conserved gene with an expanding repertoire of RNA degradation functions

(2010) S K Das et al.   ONCOGENE

Polynucleotide Phosphorylase ProtectsEscherichia coliagainst Oxidative Stress†

(2009) Jinhua Wu et al.   BIOCHEMISTRY

Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

(2009) Bayani Uttara et al.   Current Neuropharmacology

Human Mitochondrial SUV3 and Polynucleotide Phosphorylase Form a 330-kDa Heteropentamer to Cooperatively Degrade Double-stranded RNA with a 3′-to-5′ Directionality

(2009) Dennis Ding-Hwa Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel Activities of Glycolytic Enzymes inBacillus subtilis

(2009) Fabian M. Commichau et al.   MOLECULAR & CELLULAR PROTEOMICS

APE1/Ref-1 Interacts with NPM1 within Nucleoli and Plays a Role in the rRNA Quality Control Process

(2009) C. Vascotto et al.   MOLECULAR AND CELLULAR BIOLOGY

A Convergence of rRNA and mRNA Quality Control Pathways Revealed by Mechanistic Analysis of Nonfunctional rRNA Decay

(2009) Sarah E. Cole et al.   MOLECULAR CELL

Bacillus subtilis polynucleotide phosphorylase 3′-to-5′ DNase activity is involved in DNA repair

(2009) Paula P. Cardenas et al.   NUCLEIC ACIDS RESEARCH

Human polynucleotide phosphorylase reduces oxidative RNA damage and protects HeLa cell against oxidative stress

(2008) Jinhua Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

RNA under attack: Cellular handling of RNA damage

(2008) Elisabeth J. Wurtmann et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Oxidative damage and antioxidant status in patients with cervical intraepithelial neoplasia and carcinoma of the cervix

(2008) Mee-Lee Looi et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

RNA oxidation: A contributing factor or an epiphenomenon in the process of neurodegeneration

(2008) Qiongman Kong et al.   FREE RADICAL RESEARCH

Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22 and the 5'-3' exonucleases Rat1 and Xrn1

(2008) I. Chernyakov et al.   GENES & DEVELOPMENT

Sublethal RNA Oxidation as a Mechanism for Neurodegenerative Disease

(2008) Rudy Castellani et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Messenger RNA Oxidation Occurs Early in Disease Pathogenesis and Promotes Motor Neuron Degeneration in ALS

(2008) Yueming Chang et al.   PLoS One

Crystal structure of Escherichia coli PNPase: Central channel residues are involved in processive RNA degradation

(2008) Z. Shi et al.   RNA