tRNA structural and functional changes induced by oxidative stress

Molecular targets of oxidative stress

(2011) Simon V. Avery   BIOCHEMICAL JOURNAL

Desulfurization of 2-thiouracil nucleosides: Conformational studies of 4-pyrimidinone nucleosides

(2011) Karina Kraszewska et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The 2-thiouridine unit in the RNA strand is desulfured predominantly to 4-pyrimidinone nucleoside under in vitro oxidative stress conditions

(2011) Elzbieta Sochacka et al.   CHEMICAL COMMUNICATIONS

Deep-sequencing of human Argonaute-associated small RNAs provides insight into miRNA sorting and reveals Argonaute association with RNA fragments of diverse origin

(2011) Alexander Maxwell Burroughs et al.   RNA Biology

Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress

(2010) Hiroshi Hayakawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxidative damage to RNA: mechanisms, consequences, and diseases

(2010) Qiongman Kong et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

tRNA biology charges to the front

(2010) E. M. Phizicky et al.   GENES & DEVELOPMENT

RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage

(2010) M. Schaefer et al.   GENES & DEVELOPMENT

Angiogenin-induced tRNA-derived Stress-induced RNAs Promote Stress-induced Stress Granule Assembly

(2010) Mohamed M. Emara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Theoretical study on conformational preferences of ribose in 2-thiouridine—the role of the 2′OH group

(2010) Ru bo Zhang et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Human tRNA-derived small RNAs in the global regulation of RNA silencing

(2010) D. Haussecker et al.   RNA

Stressing Out over tRNA Cleavage

(2009) Debrah M. Thompson et al.   CELL

Nox proteins in signal transduction

(2009) David I. Brown et al.   FREE RADICAL BIOLOGY AND MEDICINE

A novel class of small RNAs: tRNA-derived RNA fragments (tRFs)

(2009) Yong Sun Lee et al.   GENES & DEVELOPMENT

The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress inSaccharomyces cerevisiae

(2009) Debrah M. Thompson et al.   JOURNAL OF CELL BIOLOGY

Angiogenin cleaves tRNA and promotes stress-induced translational repression

(2009) Satoshi Yamasaki et al.   JOURNAL OF CELL BIOLOGY

Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways

(2009) Jenelle M. Timmins et al.   JOURNAL OF CLINICAL INVESTIGATION

The structure of the human tRNALys3 anticodon bound to the HIV genome is stabilized by modified nucleosides and adjacent mismatch base pairs

(2009) Yann Bilbille et al.   NUCLEIC ACIDS RESEARCH

Modulation of Gene Expression by Human Cytosolic tRNase ZL through 5′-Half-tRNA

(2009) Reyad A. Elbarbary et al.   PLoS One

Structure-activity relationships in Kluyveromyces lactis  -toxin, a eukaryal tRNA anticodon nuclease

(2009) N. Keppetipola et al.   RNA

Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs

(2009) C. Cole et al.   RNA

Study of the base discrimination ability of DNA and 2′-O-methylated RNA oligomers containing 2-thiouracil bases towards complementary RNA or DNA strands and their application to single base mismatch detection

(2008) Itaru Okamoto et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Hidden layers of human small RNAs

(2008) Hideya Kawaji et al.   BMC GENOMICS

Stress induces tRNA cleavage by angiogenin in mammalian cells

(2008) Hanjiang Fu et al.   FEBS LETTERS

Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs

(2008) J. E. Babiarz et al.   GENES & DEVELOPMENT

Sublethal RNA Oxidation as a Mechanism for Neurodegenerative Disease

(2008) Rudy Castellani et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

tRNA cleavage is a conserved response to oxidative stress in eukaryotes

(2008) D. M. Thompson et al.   RNA

Watson-crick base pairs with thiocarbonyl groups: How sulfur changes the hydrogen bonds in DNA

(2008) Célia Guerra et al.   Open Chemistry

Oxidative Stress and Neurotoxicity

(2007) Lawrence M. Sayre et al.   CHEMICAL RESEARCH IN TOXICOLOGY