The role of the NLRP3 inflammasome in pulmonary diseases

Simvastatin Attenuates TGF-�1-Induced Epithelial-Mesenchymal Transition in Human Alveolar Epithelial Cells

(2013) Tuo Yang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Protective Role of Andrographolide in Bleomycin-Induced Pulmonary Fibrosis in Mice

(2013) Tao Zhu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transfusion-Related Acute Lung Injury: The Work of DAMPs*

(2013) Walter G. Land   TRANSFUSION MEDICINE AND HEMOTHERAPY

The inflammasome in lung diseases

(2012) Gimena dos Santos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The Role of the Inflammasome in Ventilator-induced Lung Injury

(2012) Claudia C. dos Santos   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Inflammasome-regulated Cytokines Are Critical Mediators of Acute Lung Injury

(2012) Tamás Dolinay et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter

(2012) Jeremy A. Hirota et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Inhibition of neutrophil apoptosis by PAI-1

(2011) Jaroslaw W. Zmijewski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Double-stranded RNA induces similar pulmonary dysfunction to respiratory syncytial virus in BALB/c mice

(2011) Famke Aeffner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cigarette smoke induces the release of CXCL-8 from human bronchial epithelial cells via TLRs and induction of the inflammasome

(2011) E. Mortaz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The inflammasome: an integrated view

(2011) Olaf Gross et al.   IMMUNOLOGICAL REVIEWS

Sputum inflammatory cells from patients with allergic rhinitis and asthma have decreased inflammasome gene expression

(2011) Willie June Brickey et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Integrating mechanisms of pulmonary fibrosis

(2011) Thomas A. Wynn   JOURNAL OF EXPERIMENTAL MEDICINE

The NLRP3 Inflammasome Is Differentially Activated by Pneumolysin Variants and Contributes to Host Defense in Pneumococcal Pneumonia

(2011) M. Witzenrath et al.   JOURNAL OF IMMUNOLOGY

Incomplete expression of epithelial–mesenchymal transition markers in idiopathic pulmonary fibrosis

(2011) Patrizia Morbini et al.   PATHOLOGY RESEARCH AND PRACTICE

Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

(2011) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammasome activation and IL-1β and IL-18 processing during infection

(2011) Frank L. van de Veerdonk et al.   TRENDS IN IMMUNOLOGY

A Potential Role for P2X7R in Allergic Airway Inflammation in Mice and Humans

(2010) Tobias Müller et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Inflammasomes: current understanding and open questions

(2010) Franz Bauernfeind et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome

(2010) Bibhuti B. Mishra et al.   CELLULAR MICROBIOLOGY

Purinergic Receptor Inhibition Prevents the Development of Smoke-Induced Lung Injury and Emphysema

(2010) S. Cicko et al.   JOURNAL OF IMMUNOLOGY

Influenza virus activates inflammasomes via its intracellular M2 ion channel

(2010) Takeshi Ichinohe et al.   NATURE IMMUNOLOGY

Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1  and IL-1 

(2010) A. S. Yazdi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans

(2009) Amy G. Hise et al.   Cell Host & Microbe

The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1

(2009) Paul G. Thomas et al.   IMMUNITY

Inflammasomes: too big to miss

(2009) Andrea Stutz et al.   JOURNAL OF CLINICAL INVESTIGATION

NAD+ and ATP Released from Injured Cells Induce P2X7-Dependent Shedding of CD62L and Externalization of Phosphatidylserine by Murine T Cells

(2009) F. Scheuplein et al.   JOURNAL OF IMMUNOLOGY

Neisseria gonorrhoeae Activates the Proteinase Cathepsin B to Mediate the Signaling Activities of the NLRP3 and ASC-Containing Inflammasome

(2009) Joseph A. Duncan et al.   JOURNAL OF IMMUNOLOGY

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

The Role of Interleukin-1β in Murine Cigarette Smoke–Induced Emphysema and Small Airway Remodeling

(2008) Andrew Churg et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Mycobacterium tuberculosis Prevents Inflammasome Activation

(2008) Sharon S. Master et al.   Cell Host & Microbe

ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection

(2008) Ingrid C. Koo et al.   CELLULAR MICROBIOLOGY

Dual-immunohistochemistry provides little evidence for epithelial–mesenchymal transition in pulmonary fibrosis

(2008) Mizuho Yamada et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

Review: Oxidant—antioxidant imbalance in asthma: scientific evidence, epidemiological data and possible therapeutic options

(2008) Ahmed Nadeem et al.   Therapeutic Advances in Respiratory Disease

Oxidative Stress, Plasminogen Activator Inhibitor 1, and Lung Fibrosis

(2007) Rui-Ming Liu   ANTIOXIDANTS & REDOX SIGNALING