标题
Inflammasomes: current understanding and open questions
作者
关键词
-
出版物
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 68, Issue 5, Pages 765-783
出版商
Springer Nature
发表日期
2010-11-12
DOI
10.1007/s00018-010-0567-4
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cutting Edge: Alum Adjuvant Stimulates Inflammatory Dendritic Cells through Activation of the NALP3 Inflammasome
- (2014) M. Kool et al. JOURNAL OF IMMUNOLOGY
- Multiple Nod-Like Receptors Activate Caspase 1 during Listeria monocytogenes Infection
- (2014) S. E. Warren et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Inflammasome Activation by Alum and Alum's Adjuvant Effect Are Mediated by NLRP3
- (2014) H. Li et al. JOURNAL OF IMMUNOLOGY
- Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome
- (2010) Sarah Kim et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Role of Potassium in Inflammasome Activation by Bacteria
- (2010) Cecilia S. Lindestam Arlehamn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
- (2010) Peter Duewell et al. NATURE
- The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
- (2010) Vijay A K Rathinam et al. NATURE IMMUNOLOGY
- The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
- (2010) Teresa Fernandes-Alnemri et al. NATURE IMMUNOLOGY
- Influenza virus activates inflammasomes via its intracellular M2 ion channel
- (2010) Takeshi Ichinohe et al. NATURE IMMUNOLOGY
- Horror Autoinflammaticus: The Molecular Pathophysiology of Autoinflammatory Disease
- (2009) Seth L. Masters et al. Annual Review of Immunology
- The Inflammasomes: Guardians of the Body
- (2009) Fabio Martinon et al. Annual Review of Immunology
- Immunological and Inflammatory Functions of the Interleukin-1 Family
- (2009) Charles A. Dinarello Annual Review of Immunology
- An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans
- (2009) Amy G. Hise et al. Cell Host & Microbe
- The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA
- (2009) Irving C. Allen et al. IMMUNITY
- The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1
- (2009) Paul G. Thomas et al. IMMUNITY
- Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases
- (2009) Alexander U. Lüthi et al. IMMUNITY
- Anthrax Lethal Toxin Triggers the Formation of a Membrane-Associated Inflammasome Complex in Murine Macrophages
- (2009) A. M. Nour et al. INFECTION AND IMMUNITY
- Interleukin-33 Is Biologically Active Independently of Caspase-1 Cleavage
- (2009) Dominique Talabot-Ayer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NLRP3/Cryopyrin Is Necessary for Interleukin-1β (IL-1β) Release in Response to Hyaluronan, an Endogenous Trigger of Inflammation in Response to Injury
- (2009) Kenshi Yamasaki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inflammasome recognition of influenza virus is essential for adaptive immune responses
- (2009) Takeshi Ichinohe et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cutting Edge: TNF- Mediates Sensitization to ATP and Silica via the NLRP3 Inflammasome in the Absence of Microbial Stimulation
- (2009) L. Franchi et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
- (2009) F. G. Bauernfeind et al. JOURNAL OF IMMUNOLOGY
- Listeria monocytogenes-Infected Human Peripheral Blood Mononuclear Cells Produce IL-1 , Depending on Listeriolysin O and NLRP3
- (2009) K. Meixenberger et al. JOURNAL OF IMMUNOLOGY
- A Critical Role for Hemolysins and Bacterial Lipoproteins in Staphylococcus aureus-Induced Activation of the Nlrp3 Inflammasome
- (2009) R. Munoz-Planillo et al. JOURNAL OF IMMUNOLOGY
- Pure Hemozoin Is Inflammatory In Vivo and Activates the NALP3 Inflammasome via Release of Uric Acid
- (2009) J. W. Griffith et al. JOURNAL OF IMMUNOLOGY
- Alum Induces Innate Immune Responses through Macrophage and Mast Cell Sensors, But These Sensors Are Not Required for Alum to Act As an Adjuvant for Specific Immunity
- (2009) A. S. McKee et al. JOURNAL OF IMMUNOLOGY
- Neisseria gonorrhoeae Activates the Proteinase Cathepsin B to Mediate the Signaling Activities of the NLRP3 and ASC-Containing Inflammasome
- (2009) Joseph A. Duncan et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Candida albicans Hyphae Formation Triggers Activation of the Nlrp3 Inflammasome
- (2009) S. Joly et al. JOURNAL OF IMMUNOLOGY
- Activation of the Nlrp3 Inflammasome by Streptococcus pyogenes Requires Streptolysin O and NF- B Activation but Proceeds Independently of TLR Signaling and P2X7 Receptor
- (2009) J. Harder et al. JOURNAL OF IMMUNOLOGY
- T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes
- (2009) Greta Guarda et al. NATURE
- AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
- (2009) Teresa Fernandes-Alnemri et al. NATURE
- AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
- (2009) Veit Hornung et al. NATURE
- Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
- (2009) Olaf Gross et al. NATURE
- RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III–transcribed RNA intermediate
- (2009) Andrea Ablasser et al. NATURE IMMUNOLOGY
- Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production
- (2009) Hendrik Poeck et al. NATURE IMMUNOLOGY
- An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
- (2009) Tilmann Bürckstümmer et al. NATURE IMMUNOLOGY
- Thioredoxin-interacting protein links oxidative stress to inflammasome activation
- (2009) Rongbin Zhou et al. NATURE IMMUNOLOGY
- Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors
- (2009) François Ghiringhelli et al. NATURE MEDICINE
- Pyroptosis: host cell death and inflammation
- (2009) Tessa Bergsbaken et al. NATURE REVIEWS MICROBIOLOGY
- Evaluation of Nod-Like Receptor (NLR) Effector Domain Interactions
- (2009) Roland N. Wagner et al. PLoS One
- Malarial Hemozoin Is a Nalp3 Inflammasome Activating Danger Signal
- (2009) Catherine Dostert et al. PLoS One
- Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome
- (2009) Fiona A. Sharp et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanism of Bcl-2 and Bcl-XL inhibition of NLRP1 inflammasome: Loop domain-dependent suppression of ATP binding and oligomerization
- (2009) B. Faustin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1
- (2009) C. Cayrol et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA
- (2009) T. L. Roberts et al. SCIENCE
- Malarial Hemozoin Activates the NLRP3 Inflammasome through Lyn and Syk Kinases
- (2009) Marina Tiemi Shio et al. PLoS Pathogens
- Differential requirement for the activation of the inflammasome for processing and release of IL-1 in monocytes and macrophages
- (2008) M. G. Netea et al. BLOOD
- The leucine-rich repeat structure
- (2008) J. Bella et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Killing of macrophages by anthrax lethal toxin: involvement of the N-end rule pathway
- (2008) Katherine E. Wickliffe et al. CELLULAR MICROBIOLOGY
- Alum adjuvanticity: Unraveling a century old mystery
- (2008) Ennio De Gregorio et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1β secretion but dispensable for adjuvant activity
- (2008) Luigi Franchi et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Initial description of the human NLRP3 promoter
- (2008) J P Anderson et al. GENES AND IMMUNITY
- The NLR Gene Family: A Standard Nomenclature
- (2008) Jenny P.-Y. Ting et al. IMMUNITY
- Interferon-inducible Ifi200-family genes in systemic lupus erythematosus
- (2008) Divaker Choubey et al. IMMUNOLOGY LETTERS
- TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
- (2008) Ken J. Ishii et al. NATURE
- The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
- (2008) Daniel A. Muruve et al. NATURE
- Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
- (2008) Stephanie C. Eisenbarth et al. NATURE
- Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin
- (2008) Karla L Lightfield et al. NATURE IMMUNOLOGY
- Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
- (2008) Veit Hornung et al. NATURE IMMUNOLOGY
- The NALP3 inflammasome is involved in the innate immune response to amyloid-β
- (2008) Annett Halle et al. NATURE IMMUNOLOGY
- The Nalp3 inflammasome is essential for the development of silicosis
- (2008) Suzanne L. Cassel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A NOD2-NALP1 complex mediates caspase-1-dependent IL-1 secretion in response to Bacillus anthracis infection and muramyl dipeptide
- (2008) L.-C. Hsu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pseudomonas aeruginosa activates caspase 1 through Ipaf
- (2008) E. A. Miao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms
- (2008) S. L. Fink et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1 and IL-18 secretion in an autocrine way
- (2008) A. Piccini et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica
- (2008) C. Dostert et al. SCIENCE
- Engagement of NOD2 has a dual effect on proIL-1β mRNA transcription and secretion of bioactive IL-1β
- (2007) Gerben Ferwerda et al. EUROPEAN JOURNAL OF IMMUNOLOGY
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