标题
Regularized Machine Learning in the Genetic Prediction of Complex Traits
作者
关键词
-
出版物
PLoS Genetics
Volume 10, Issue 11, Pages e1004754
出版商
Public Library of Science (PLoS)
发表日期
2014-11-14
DOI
10.1371/journal.pgen.1004754
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Assessing multivariate gene-metabolome associations with rare variants using Bayesian reduced rank regression
- (2014) Pekka Marttinen et al. BIOINFORMATICS
- Prediction of Fetal Hemoglobin in Sickle Cell Anemia Using an Ensemble of Genetic Risk Prediction Models
- (2014) J. N. Milton et al. Circulation-Cardiovascular Genetics
- MultiBLUP: improved SNP-based prediction for complex traits
- (2014) Doug Speed et al. GENOME RESEARCH
- Advantages and pitfalls in the application of mixed-model association methods
- (2014) Jian Yang et al. NATURE GENETICS
- Improving the Accuracy of Whole Genome Prediction for Complex Traits Using the Results of Genome Wide Association Studies
- (2014) Zhe Zhang et al. PLoS One
- Exploiting SNP Correlations within Random Forest for Genome-Wide Association Studies
- (2014) Vincent Botta et al. PLoS One
- Genome-wide Association Analysis for Multiple Continuous Secondary Phenotypes
- (2013) Elizabeth D. Schifano et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Large Sample Size, Wide Variant Spectrum, and Advanced Machine-Learning Technique Boost Risk Prediction for Inflammatory Bowel Disease
- (2013) Zhi Wei et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Network-guided sparse regression modeling for detection of gene-by-gene interactions
- (2013) Chen Lu et al. BIOINFORMATICS
- PleioGRiP: genetic risk prediction with pleiotropy
- (2013) S. W. Hartley et al. BIOINFORMATICS
- ETHNOPRED: a novel machine learning method for accurate continental and sub-continental ancestry identification and population stratification correction
- (2013) Mohsen Hajiloo et al. BMC BIOINFORMATICS
- Predicting phenotypic variation from genotypes, phenotypes and a combination of the two
- (2013) Alejandro Burga et al. CURRENT OPINION IN BIOTECHNOLOGY
- Strategies for Developing Prediction Models From Genome-Wide Association Studies
- (2013) Jincao Wu et al. GENETIC EPIDEMIOLOGY
- Genetic Prediction of Quantitative Lipid Traits: Comparing Shrinkage Models to Gene Scores
- (2013) Helen Warren et al. GENETIC EPIDEMIOLOGY
- Genetic and Nongenetic Variation Revealed for the Principal Components of Human Gene Expression
- (2013) Anita Goldinger et al. GENETICS
- Genome-Wide Prediction of Traits with Different Genetic Architecture Through Efficient Variable Selection
- (2013) V. Wimmer et al. GENETICS
- Building a Genome Analysis Pipeline to Predict Disease Risk and Prevent Disease
- (2013) Y. Bromberg JOURNAL OF MOLECULAR BIOLOGY
- Epigenetic epistatic interactions constrain the evolution of gene expression
- (2013) S. Park et al. Molecular Systems Biology
- Negligible impact of rare autoimmune-locus coding-region variants on missing heritability
- (2013) Karen A. Hunt et al. NATURE
- Finding the sources of missing heritability in a yeast cross
- (2013) Joshua S. Bloom et al. NATURE
- Combined sequence-based and genetic mapping analysis of complex traits in outbred rats
- (2013) Amelie Baud et al. NATURE GENETICS
- Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studies
- (2013) Nilanjan Chatterjee et al. NATURE GENETICS
- Genotype to phenotype: lessons from model organisms for human genetics
- (2013) Ben Lehner NATURE REVIEWS GENETICS
- Integrative approaches for finding modular structure in biological networks
- (2013) Koyel Mitra et al. NATURE REVIEWS GENETICS
- Pleiotropy in complex traits: challenges and strategies
- (2013) Nadia Solovieff et al. NATURE REVIEWS GENETICS
- Bringing genome-wide association findings into clinical use
- (2013) Teri A. Manolio NATURE REVIEWS GENETICS
- Pitfalls of predicting complex traits from SNPs
- (2013) Naomi R. Wray et al. NATURE REVIEWS GENETICS
- Genome-wide association studies with high-dimensional phenotypes
- (2013) Pekka Marttinen et al. Statistical Applications in Genetics and Molecular Biology
- From personalized to public health genomics
- (2013) Greg Gibson et al. Genome Medicine
- Incremental value of rare genetic variants for the prediction of multifactorial diseases
- (2013) Raluca Mihaescu et al. Genome Medicine
- PUMA: A Unified Framework for Penalized Multiple Regression Analysis of GWAS Data
- (2013) Gabriel E. Hoffman et al. PLoS Computational Biology
- Predicting Disease Risk Using Bootstrap Ranking and Classification Algorithms
- (2013) Ohad Manor et al. PLoS Computational Biology
- Robust Prediction of Expression Differences among Human Individuals Using Only Genotype Information
- (2013) Ohad Manor et al. PLoS Genetics
- Pathways-Driven Sparse Regression Identifies Pathways and Genes Associated with High-Density Lipoprotein Cholesterol in Two Asian Cohorts
- (2013) Matt Silver et al. PLoS Genetics
- Prediction of Complex Human Traits Using the Genomic Best Linear Unbiased Predictor
- (2013) Gustavo de los Campos et al. PLoS Genetics
- Low Frequency Variants, Collapsed Based on Biological Knowledge, Uncover Complexity of Population Stratification in 1000 Genomes Project Data
- (2013) Carrie B. Moore et al. PLoS Genetics
- Power and Predictive Accuracy of Polygenic Risk Scores
- (2013) Frank Dudbridge PLoS Genetics
- Polygenic Modeling with Bayesian Sparse Linear Mixed Models
- (2013) Xiang Zhou et al. PLoS Genetics
- GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm
- (2013) Leonardo Bottolo et al. PLoS Genetics
- Genetic variants and their interactions in disease risk prediction – machine learning and network perspectives
- (2013) Sebastian Okser et al. BioData Mining
- Using Bayesian networks to discover relations between genes, environment, and disease
- (2013) Chengwei Su et al. BioData Mining
- eQTL Epistasis – Challenges and Computational Approaches
- (2013) Yang Huang et al. Frontiers in Genetics
- Evaluation of the lasso and the elastic net in genome-wide association studies
- (2013) Patrik Waldmann et al. Frontiers in Genetics
- Wrapper-based selection of genetic features in genome-wide association studies through fast matrix operations
- (2012) Tapio Pahikkala et al. Algorithms for Molecular Biology
- synbreed: a framework for the analysis of genomic prediction data using R
- (2012) Valentin Wimmer et al. BIOINFORMATICS
- A scalable and portable framework for massively parallel variable selection in genetic association studies
- (2012) Gary K. Chen BIOINFORMATICS
- A Lasso multi-marker mixed model for association mapping with population structure correction
- (2012) Barbara Rakitsch et al. BIOINFORMATICS
- SparSNP: Fast and memory-efficient analysis of all SNPs for phenotype prediction
- (2012) Gad Abraham et al. BMC BIOINFORMATICS
- Network biology methods integrating biological data for translational science
- (2012) G. Bebek et al. BRIEFINGS IN BIOINFORMATICS
- Machine learning approaches for the discovery of gene-gene interactions in disease data
- (2012) R. Upstill-Goddard et al. BRIEFINGS IN BIOINFORMATICS
- Beyond genotype to phenotype: why the phenotype of an individual cannot always be predicted from their genome sequence and the environment that they experience
- (2012) Alejandro Burga et al. FEBS Journal
- Performance and Robustness of Penalized and Unpenalized Methods for Genetic Prediction of Complex Human Disease
- (2012) Gad Abraham et al. GENETIC EPIDEMIOLOGY
- Risk estimation and risk prediction using machine-learning methods
- (2012) Jochen Kruppa et al. HUMAN GENETICS
- Improving the Prediction of Clinical Outcomes from Genomic Data Using Multiresolution Analysis
- (2012) Pablo H. Hennings-Yeomans et al. IEEE-ACM Transactions on Computational Biology and Bioinformatics
- Correction for population stratification in random forest analysis
- (2012) Yang Zhao et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Rare and common variants: twenty arguments
- (2012) Greg Gibson NATURE REVIEWS GENETICS
- Identification of gene pathways implicated in Alzheimer's disease using longitudinal imaging phenotypes with sparse regression
- (2012) Matt Silver et al. NEUROIMAGE
- Bayesian Variable Selection in Searching for Additive and Dominant Effects in Genome-Wide Data
- (2012) Tomi Peltola et al. PLoS One
- Cancer heterogeneity: origins and implications for genetic association studies
- (2012) Davnah Urbach et al. TRENDS IN GENETICS
- Chapter 11: Genome-Wide Association Studies
- (2012) William S. Bush et al. PLoS Computational Biology
- Use of Pleiotropy to Model Genetic Interactions in a Population
- (2012) Gregory W. Carter et al. PLoS Genetics
- Comparison of Family History and SNPs for Predicting Risk of Complex Disease
- (2012) Chuong B. Do et al. PLoS Genetics
- Lessons from Model Organisms: Phenotypic Robustness and Missing Heritability in Complex Disease
- (2012) Christine Queitsch et al. PLoS Genetics
- Using Whole-Genome Sequence Data to Predict Quantitative Trait Phenotypes in Drosophila melanogaster
- (2012) Ulrike Ober et al. PLoS Genetics
- Novel Loci for Metabolic Networks and Multi-Tissue Expression Studies Reveal Genes for Atherosclerosis
- (2012) Michael Inouye et al. PLoS Genetics
- A Hierarchical Bayesian Approach to Multi-Trait Clinical Quantitative Trait Locus Modeling
- (2012) Crispin M. Mutshinda et al. Frontiers in Genetics
- Bayesian Methods for Multivariate Modeling of Pleiotropic SNP Associations and Genetic Risk Prediction
- (2012) Stephen W. Hartley et al. Frontiers in Genetics
- Naïve Bayesian Classifier and Genetic Risk Score for Genetic Risk Prediction of a Categorical Trait: Not so Different after all!
- (2012) Paola Sebastiani et al. Frontiers in Genetics
- Gene-gene interaction filtering with ensemble of filters
- (2011) Pengyi Yang et al. BMC BIOINFORMATICS
- Random forest Gini importance favours SNPs with large minor allele frequency: impact, sources and recommendations
- (2011) A.-L. Boulesteix et al. BRIEFINGS IN BIOINFORMATICS
- Genetic Interactions in Cancer Progression and Treatment
- (2011) Alan Ashworth et al. CELL
- Searching for synthetic lethality in cancer
- (2011) Rachel Brough et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Mining gold dust under the genome wide significance level: a two-stage approach to analysis of GWAS
- (2011) Gang Shi et al. GENETIC EPIDEMIOLOGY
- Predicting Genetic Values: A Kernel-Based Best Linear Unbiased Prediction With Genomic Data
- (2011) Ulrike Ober et al. GENETICS
- Genetic risk prediction in complex disease
- (2011) Luke Jostins et al. HUMAN MOLECULAR GENETICS
- Molecular mechanisms of epistasis within and between genes
- (2011) Ben Lehner TRENDS IN GENETICS
- Beyond Missing Heritability: Prediction of Complex Traits
- (2011) Robert Makowsky et al. PLoS Genetics
- The Bayesian lasso for genome-wide association studies
- (2010) Jiahan Li et al. BIOINFORMATICS
- Bioinformatics challenges for genome-wide association studies
- (2010) J. H. Moore et al. BIOINFORMATICS
- Association screening of common and rare genetic variants by penalized regression
- (2010) H. Zhou et al. BIOINFORMATICS
- A variable selection method for genome-wide association studies
- (2010) Qianchuan He et al. BIOINFORMATICS
- An application of Random Forests to a genome-wide association dataset: Methodological considerations & new findings
- (2010) Benjamin A Goldstein et al. BMC GENETICS
- Risk prediction using genome-wide association studies
- (2010) Charles Kooperberg et al. GENETIC EPIDEMIOLOGY
- A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses
- (2010) Samuli Ripatti et al. LANCET
- Clinical assessment incorporating a personal genome
- (2010) Euan A Ashley et al. LANCET
- Hints of hidden heritability in GWAS
- (2010) Greg Gibson NATURE GENETICS
- Common SNPs explain a large proportion of the heritability for human height
- (2010) Jian Yang et al. NATURE GENETICS
- Missing heritability and strategies for finding the underlying causes of complex disease
- (2010) Evan E. Eichler et al. NATURE REVIEWS GENETICS
- Beyond genome-wide association studies: genetic heterogeneity and individual predisposition to cancer
- (2010) Antonella Galvan et al. TRENDS IN GENETICS
- Genetic Variants and Their Interactions in the Prediction of Increased Pre-Clinical Carotid Atherosclerosis: The Cardiovascular Risk in Young Finns Study
- (2010) Sebastian Okser et al. PLoS Genetics
- Epistasis and Its Implications for Personal Genetics
- (2009) Jason H. Moore et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genome-wide association analysis by lasso penalized logistic regression
- (2009) Tong Tong Wu et al. BIOINFORMATICS
- Performance of random forest when SNPs are in linkage disequilibrium
- (2009) Yan A Meng et al. BMC BIOINFORMATICS
- Machine learning in genome-wide association studies
- (2009) Silke Szymczak et al. GENETIC EPIDEMIOLOGY
- Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk
- (2009) David M. Evans et al. HUMAN MOLECULAR GENETICS
- Beyond odds ratios — communicating disease risk based on genetic profiles
- (2009) Peter Kraft et al. NATURE REVIEWS GENETICS
- Detecting gene–gene interactions that underlie human diseases
- (2009) Heather J Cordell NATURE REVIEWS GENETICS
- Capturing the Spectrum of Interaction Effects in Genetic Association Studies by Simulated Evaporative Cooling Network Analysis
- (2009) Brett A. McKinney et al. PLoS Genetics
- Interpretation of Genetic Association Studies: Markers with Replicated Highly Significant Odds Ratios May Be Poor Classifiers
- (2009) Johanna Jakobsdottir et al. PLoS Genetics
- From Disease Association to Risk Assessment: An Optimistic View from Genome-Wide Association Studies on Type 1 Diabetes
- (2009) Zhi Wei et al. PLoS Genetics
- Accommodating Linkage Disequilibrium in Genetic-Association Analyses via Ridge Regression
- (2008) Nathalie Malo et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Personal genomes: The case of the missing heritability
- (2008) Brendan Maher NATURE
- Spectral Algorithms for Supervised Learning
- (2008) L. Lo Gerfo et al. NEURAL COMPUTATION
- Simultaneous Analysis of All SNPs in Genome-Wide and Re-Sequencing Association Studies
- (2008) Clive J. Hoggart et al. PLoS Genetics
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search